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  • 1
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    Cambridge, UK ; New York : Cambridge University Press
    Keywords: United States, Politics and government, 1963-1969. ; United States, Politics and government, 1969-1974. ; Vietnamese Conflict, 1961-1975, Protest movements, United States. ; Vietnamese Conflict, 1961-1975, United States.
    Notes: Anti-imperialism in U.S. foreign relations / Frank Ninkovich -- World War II, congress, and the roots of postwar American foreign policy / Randall B. Woods -- The progressive dissent: Ernest Gruening and Vietnam / Robert D. Johnson -- "Come home, America": the story of George McGovern / Thomas J. Knock -- Congress must draw the line: Senator Frank Church and the opposition to the Vietnam War and the imperial presidency / David F. Schmitz -- Dixie's dove: J. William Fulbright, the Vietnam War, and the American South / Randall B. Woods -- Advice and dissent: Mike Mansfield and the Vietnam War / Donald A. Ritchie -- The reluctant "volunteer": the origins of Senator Albert A. Gore's opposition to the Vietnam War / Kyle Longley -- A delicate balance: John Sherman Cooper and the Republican opposition to the Vietnam War / Fredrik Logevall -- Friendly fire: Lyndon Johnson and the challenge to containment / H.W. Brands -- Richard Nixon, congress, and the war in Vietnam, 1969-1974 / Robert D. Schulzinger
    Pages: vii, 324 p.
    ISBN: 0-511-06448-9
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  • 2
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    Upper Saddle River, N.J. : Prentice Hall
    Call number: B040:170
    Keywords: Image processing / Digital techniques
    Pages: xx, 793 p. : ill.
    Edition: 2nd ed.
    ISBN: 0201180758
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  • 3
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    Reading, Mass. : Addison-Wesley Pub. Co
    Call number: 09-EDV:1496
    Keywords: Image processing / Digital techniques
    Notes: Reprinted with corrections. - Originally published: c1992.
    Pages: xvi ,716 p. : ill. pbk
    ISBN: 0201600781
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  • 4
    Keywords: Mass spectrometry ; Proteomics ; Biomedical Engineering ; Mass spectrometry ; Proteomics ; Biomedical Engineering/Biotechnology ; Biomedical Engineering and Bioengineering ; Springer eBooks
    Description / Table of Contents: Mass Spectrometry for Proteomics-based Investigation -- MALDI profiling and applications in medicine -- Applications of Matrix-Assisted Laser Desorption Ionization In-Source Decay Mass Spectrometry -- Proteome imaging: from classic to modern mass spectrometry-based molecular histology -- Mass Spectrometry-Based Tissue Imaging of Small Molecules -- Sequencing Proteins from Bottom to Top: Combining Techniques for Full Sequence Analysis of Glucokinase -- Proteomics and non-proteomics approaches to study stable and transient protein-protein interactions -- Contribution of Mass spectrometry-based Proteomics to Discoveries in Developmental Biology -- Profiling optimal conditions for capturing EDEM proteins complexes in melanoma using mass spectrometry -- The Methods employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein–Protein Interactions (PPIs) -- Identification of post-translational modifications (PTMs) of proteins by mass spectrometry -- Sequence Variant and Post-translational Modification Analysis During Cell Line Selection via High-throughput Peptide Mapping -- Selective derivatization of hexahistidine-tagged recombinant proteins -- Investigation of Antibody-Drug Conjugates by Mass Spectrometry -- Mass Spectrometry- and Computational Structural Biology-Based Investigation of Proteins and Peptides -- Strategies for Membrane Protein Analysis by Mass Spectrometry -- The Potential for Ion Mobility in Pharmaceutical and Clinical Analyses -- Application of Ion Mobility Mass Spectrometry in Lipidomics -- Mass Spectrometry in Advancement of Redox Precision Medicine -- Applications for mass spectrometry in the study of ion channel structure and function -- Immuno – affinity Mass Spectrometry: A Novel Approaches with Biomedical Relevance -- Developing well-annotated species-specific protein databases using comparative proteogenomics -- Stoichiometry of heavy metal binding to peptides involved in Alzheimer’s disease: mass spectrometric evidence -- Role of mass spectrometry in investigating a novel protein: the example of Tumor Differentiation Factor (TDF) -- Mass Spectrometry-Based Biomarkers in Drug Developmen -- Combinatorial Electrophoresis and Mass Spectrometry-Based Proteomics in Breast Milk for Breast Cancer Biomarker Discovery -- Proteomic approaches to dissect neuronal signalling pathways -- Mass Spectrometry for the Study of Autism and Neurodevelopmental Disorders -- Simplifying the proteome: Analytical strategies for improving peak capacity -- Exploration of nicotine metabolism in Paenarthrobacter nicotinovorans pAO1 by microbial proteomics -- Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) for Quantitative Proteomics -- Mass spectrometry based comparative proteomics using one dimensional and two dimensional SDS-PAGE of rat atria induced with obstructive sleep apnea -- 2D SDS PAGE in combination with western blotting and mass spectrometry is a robust method for protein analysis with many applications -- Pulse SILAC approaches to the measurement of cellular dynamics -- Protein Biomarkers in Major Depressive Disorder: an Update -- A Pilot Exploratory Proteomics Investigation of Mental Fatigue and Mental Energy -- Metabolomics and biomarker discovery -- Analytical Methods for Mass Spectrometry-Based Metabolomics Studies -- Trends in analysis of cortisol and its derivatives -- Detection of biomedically relevant stilbenes from wines by mass spectrometry -- Mass spectrometry as a complementary approach for noncovalently bound complexes based on cyclodextrins -- Trends in glycolipid biomarker discovery in neurodegenerative disorders by mass spectrometry -- Non-targeted Screening in Environmental Monitoring Programs -- Mass Spectrometric DNA Adduct Quantification by Multiple Reaction Monitoring and its Future Use for the Molecular Epidemiology of Cancer -- Bottlenecks in proteomics: an update -- Recent Applications of Mass Spectrometry at Clarkson University -- Index
    Abstract: This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field
    Pages: XXI, 813 p. 362 illus., 310 illus. in color. : online resource.
    Edition: 2nd ed. 2019.
    ISBN: 9783030159504
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  • 5
    ISSN: 0168-9002
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 352 (1991), S. 368-368 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR — Your correspondent W. F. J. Cuthbertson attributes the development of refrigeration for preserving food to the invention of the compression expansion refrigerator in 1872 (Nature 351, 434; 1991). The history of food refrigeration is in fact considerably longer. The principle was ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 185 (1960), S. 157-158 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Photographs were taken using copper Ka. radiation in an evacuated camera at specimen-film distances of 24 and 20 cm. The six forms of oc-keratin studied gave photographs that fall into three groups: group A, porcupine quill tip; group B〉 Lincoln wool and kid mohair; group (7, human hair, horse hair ...
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-2072
    Keywords: Key words Capsaicin ; Peripheral opioid receptor ; Antinociception ; Neurogenic inflammation ; Hyperalgesia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Rationale: By acting on peripheral opioid receptors, opioid agonists can attenuate nociceptive responses induced by a variety of agents. Objectives: This study was conducted to characterize capsaicin-induced thermal hyperalgesia in rats and to evaluate the hypothesis that local administration of either mu or kappa opioid agonists (fentanyl and U50,488, respectively) can attenuate capsaicin-induced nociception. Methods: Capsaicin was administered s.c. in the tail of rats to evoke a nociceptive response, which was measured by the warm-water tail-withdrawal procedure. Either fentanyl or U50,488 was co-administered with capsaicin in the tail to evaluate local antinociceptive effects. In addition, the local antagonism study was performed to confirm the site of action of both opioid agonists. Results: Capsaicin (0.3–10 µg) dose dependently produced thermal hyperalgesia manifested as reduced tail-withdrawal latencies in 45°C water. Co-administration of either fentanyl (0.32–3.2 µg) or U50,488 (10–100 µg) with capsaicin (3 µg) attenuated capsaicin-induced hyperalgesia in a dose-dependent manner. Furthermore, this local antinociception was antagonized by small doses (10–100 µg) of an opioid antagonist, quadazocine, applied s.c. in the tail. However, the locally effective doses of quadazocine, when applied s.c. in the back (i.e., around the scapular region), did not antagonize either fentanyl or U50,488. Conclusions: In this experimental pain model, activation of peripheral mu or kappa opioid receptors can attenuate capsaicin-induced thermal hyperalgesia in rats. It supports the notion that peripheral antinociception can be achieved by local administration of analgesics into the injured tissue without producing central side effects.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-203X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract An efficient protocol has been developed for the in vitro propagation of Mexican Weeping Bamboo through somatic embryogenesis from zygotic embryo explants. Mature seeds and excised embryos were cultured in the light or in the dark on both Murashige and Skoog's and Gamborg's B5 basal media with various supplements. Optimal somatic embryogenesis and plant regeneration were obtained by culture in the dark on Murashige and Skoog's basal medium supplemented with 3 mg/1 2,4-dichlorophenoxyacetic acid, 0.5 mg/1 6-benzylaminopurine and 2.0% sucrose. More than 95% of the germinating somatic embryos developed shoots and roots, and were transferred to soil with 85% success.
    Type of Medium: Electronic Resource
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  • 10
    Keywords: CANCER ; radiotherapy ; SURVIVAL ; SYSTEM ; VOLUME ; MORTALITY ; PATIENT ; QUALITY ; CONTRAST ; MALIGNANCIES ; PATTERNS ; DIFFERENCE ; CANCER-PATIENTS ; CHILDREN ; CANCER PATIENTS ; TRENDS ; INEQUALITIES ; MALIGNANCY ; ONCOLOGY ; ADULT ; ADULTS ; RE ; PATTERN ; PATIENT SURVIVAL ; overall survival ; SUPPLEMENT ; analysis ; methods ; CANCERS ; ENGLAND ; cancer survival ; EARLY BREAST-CANCER ; WALES ; discussion ; socioeconomic status ; UK ; SOCIAL-CLASS ; RANDOMIZED-TRIALS ; DEPRIVATION ; SOCIOECONOMIC INEQUALITIES ; 15-YEAR SURVIVAL ; DISPARITIES
    Abstract: Survival has risen steadily since the 1970s for most cancers in adults in England and Wales, but persistent inequalities exist between those living in affluent and deprived areas. These differences are not seen for children. For many of the common adult cancers, these inequalities in survival ( the 'deprivation gap') became more marked in the 1990s. This volume presents extended analyses of survival for adults diagnosed during the 14 years 1986-1999 and followed up to 2001, including trends in overall survival in England and Wales and trends in the deprivation gap in survival. The analyses include individual tumour data for 2.2 million cancer patients. This article outlines the structure of the supplement - an article for each of the 20 most common cancers in adults, followed by an expert commentary from one of the leading UK clinicians specialising in malignancies of that organ or system. The available data, quality control and methods of analysis are described here, rather than repeated in each of the 20 articles. We open the discussion between clinicians and epidemiologists on how to interpret the observed trends and inequalities in cancer survival, and we highlight some of the most important contrasts in these very different points of view. Survival improved substantially for adult cancer patients in England and Wales up to the end of the 20th century. Although socioeconomic inequalities in survival are remarkably persistent, the overall patterns suggest that these inequalities are largely avoidable
    Type of Publication: Journal article published
    PubMed ID: 18813248
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