Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    facet.materialart.
    Unknown
    German Medical Science GMS Publishing House; Düsseldorf
    In:  17. Jahreskongress für Klinische Pharmakologie; 20151001-20151002; Köln; DOC15vklipha30 /20150924/
    Publication Date: 2015-09-25
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
    Signatur Availability
    BibTip Others were also interested in ...
  • 2
    facet.materialart.
    Unknown
    German Medical Science GMS Publishing House; Düsseldorf
    In:  10. Deutscher Kongress für Versorgungsforschung; 18. GAA-Jahrestagung; 20111020-20111022; Köln; DOC11dkvf139 /20111012/
    Publication Date: 2011-10-12
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
    Signatur Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1432-0584
    Keywords: Key words Candida pneumonia ; Aspergillosis ; Bronchoscopy ; High resolution CT scan
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  In a retrospective study of 56 patients with hematological malignancies and fungal pneumonia we have analyzed the value of different diagnostic procedures. In all patients (Candida n = 29, Aspergillus n = 23, mixed fungal infection n = 4) bronchoscopy and/or high-resolution computed tomography of the lungs was performed. Cultural detection of fungi in bronchoalveolar lavage was successful in 23/32 Candida and 11/23 Aspergillus pneumonias. Other relevant pathogens were identified by bronchoscopy in 21 cases. Thorax CT scans showed diagnostic evidence of fungal pneumonia in 10/13 Candida and in 16/18 Aspergillus infections. Blood cultures were positive in 9/33 Candida pneumonias and in none of aspergillosis cases. Serological testing and surveillance cultures had only limited value for the early diagnosis of pulmonary mycosis. Our data suggest that bronchoscopy and high resolution CT scans are mutually complementary diagnostic tools with high sensitivity in patients with hematological malignancies and new pulmonary infiltrates. These procedures facilitate the early and reliable recognition of invasive fungal disease which may have a bearing on the initiation, length, and differential therapy of antimycotic drugs.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1432-0584
    Keywords: Candida pneumonia ; Aspergillosis ; Bronchoscopy ; High resolution CT scan
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a retrospective study of 56 patients with hematological malignancies and fungal pneumonia we have analyzed the value of different diagnostic procedures. In all patients (Candida n=29,Aspergillus n=23, mixed fungal infectionn=4) bronchoscopy and/or high-resolution computed tomography of the lungs was performed. Cultural detection of fungi in bronchoalveolar lavage was successful in 23/32Candida and 11/23Aspergillus pneumonias. Other relevant pathogens were identified by bronchoscopy in 21 cases. Thorax CT scans showed diagnostic evidence of fungal pneumonia in 10/13Candida and in 16/18Aspergillus infections. Blood cultures were positive in 9/33Candida pneumonias and in none of aspergillosis cases. Serological testing and surveillance cultures had only limited value for the early diagnosis of pulmonary mycosis. Our data suggest that bronchoscopy and high resolution CT scans are mutually complementary diagnostic tools with high sensitivity in patients with hematological malignancies and new pulmonary infiltrates. These procedures facilitate the early and reliable recognition of invasive fungal disease which may have a bearing on the initiation, length, and differential therapy of antimycotic drugs.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Cefpodoxim entsteht durch Spaltung des Esters aus dem resorbierbaren Cefpodoxim-Proxetil und ist gegen die meistenEnterobacteriaceae mit MHK50-Werten von 0,06 bis 2 mg/l aktiv. Nur Stämme vonEnterobacter cloacae undCitrobacter freundii zeigen MHK50-Werte von 4 mg/l. Coagulase negative Staphylokokken haben eine MHK50 von 2, währendStaphylococcus aureus-Stämme eine MHK von 4 mg/l aufweisen. Im Vergleich mit anderen oral verfügbaren Cephalosporinen ist Cefpodoxim gegen gramnegative Bakterien etwas weniger aktiv als Cefixim und Cefotiam, aber aktiver als Cefuroxim, Cefaclor und Cephalexin. Gegen Staphylokokken ist die Aktivität von Cefpodoxim mit der von Cefotiam und Cefuroxim vergleichbar und der von Cefaclor und Cephalexin überlegen, während Cefixim keine ausreichende Aktivität gegen diese Spezies hat. Wie alle Cephalosporine weist Cefpodoxim keine Aktivität gegen Enterokokken auf.
    Notes: Summary Cefpodoxime, the deesterified part of the orally available cefpodoxime proxetil, is active against mostEnterobacteriaceae with MIC50 of 0.06 to 2 mg/l. OnlyEnterobacter cloacae andCitrobacter freundii strains show MIC50 of 4 mg/l. Coagulase negative staphylococci have a MIC50 of 2, whileStaphylococcus aureus strains have a MIC of 4 mg/l. In comparison to other orally available cephalosporins cefpodoxime is slightly less active than cefixime and cefotiam against gram-negative bacteria but more active than cefuroxime, cefaclor, and cephalexin. Against staphylococci the activity of cefpodoxime is comparable to that of cefotiam and cefuroxime and superior to cefaclor and cephalexin, while cefixime does not have sufficient activity against these species. Like all cephalosporins cefpodoxime has no activity against enterococci.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1432-1750
    Keywords: Bronchoalveolar lavage (BAL) ; Pneumonia ; Neutropenia ; Differential cell count ; Lymphocyte subsets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract One hundred immunocompromised HIV negative patients with microbiologically positive pneumonia underwent bronchoalveolar lavage (BAL) studies. Thirty cases showed peripheral neutropenia (〈1000 neutrophils/μL), Neutrophils per microliter. 70 did not. The total cell number in BAL, the differential cell counts, and the lymphocyte subsets (CD4, CD8, CD19, CD57) were measured. Patients with pneumonia and normal or elevated peripheral neutrophils had a significantly increased total number of cells in BAL compared to patients with peripheral neutropenia (3,2 ± 2 vs 1,3 ± 0,6 × 105 cells/ml Cells per milliliter. lavage fluid, p 〈 0.01). Ninety percent of the BAL differential cell counts obtained in patients exceeding 1000 neutrophils/μL showed a lymphocytic and/or neutrophilic alveolitis, whereas only 54% of patients with peripheral neutropenia displayed abnormal counts (p 〈 0.01). Yet the typical pattern of neutrophilic alveolitis was found more often for peripheral neutrophil counts over 1000/μL with high significance (p 〈 0.0001). Abnormal BAL cell patterns for neutropenic patients uniformly showed a lymphocytic alveolitis, only 10% additionally conformed with the pattern of neutrophilic alveolitis. Patients with pneumonia with and without peripheral neutropenia had similar findings in BAL lymphocyte subsets and exhibited a reduced CD4/CD8 ratio compared to controls (p 〈 0.05). The high susceptibility of severe neutropenic patients to pulmonary, especially fungal infections may be explained by the local lack of neutrophils.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...