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  • 1
    Publication Date: 2018-10-02
    Description: Multibandgap quantum dot ensembles for solar-matched infrared energy harvesting Multibandgap quantum dot ensembles for solar-matched infrared energy harvesting, Published online: 01 October 2018; doi:10.1038/s41467-018-06342-7 Efficient harvest of solar energy beyond the silicon absorption edge of 1100 nm by semiconductor solar cells remains a challenge. Here Sun et al. mix high multi-bandgap lead sulfide colloidal quantum dot ensembles to further increase both short circuit current and open circuit voltage.
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2012-03-17
    Description: Matter structured on a length scale comparable to or smaller than the wavelength of light can exhibit unusual optical properties. Particularly promising components for such materials are metal nanostructures, where structural alterations provide a straightforward means of tailoring their surface plasmon resonances and hence their interaction with light. But the top-down fabrication of plasmonic materials with controlled optical responses in the visible spectral range remains challenging, because lithographic methods are limited in resolution and in their ability to generate genuinely three-dimensional architectures. Molecular self-assembly provides an alternative bottom-up fabrication route not restricted by these limitations, and DNA- and peptide-directed assembly have proved to be viable methods for the controlled arrangement of metal nanoparticles in complex and also chiral geometries. Here we show that DNA origami enables the high-yield production of plasmonic structures that contain nanoparticles arranged in nanometre-scale helices. We find, in agreement with theoretical predictions, that the structures in solution exhibit defined circular dichroism and optical rotatory dispersion effects at visible wavelengths that originate from the collective plasmon-plasmon interactions of the nanoparticles positioned with an accuracy better than two nanometres. Circular dichroism effects in the visible part of the spectrum have been achieved by exploiting the chiral morphology of organic molecules and the plasmonic properties of nanoparticles, or even without precise control over the spatial configuration of the nanoparticles. In contrast, the optical response of our nanoparticle assemblies is rationally designed and tunable in handedness, colour and intensity-in accordance with our theoretical model.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kuzyk, Anton -- Schreiber, Robert -- Fan, Zhiyuan -- Pardatscher, Gunther -- Roller, Eva-Maria -- Hogele, Alexander -- Simmel, Friedrich C -- Govorov, Alexander O -- Liedl, Tim -- England -- Nature. 2012 Mar 14;483(7389):311-4. doi: 10.1038/nature10889.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Physik Department and ZNN/WSI, Technische Universitat Munchen, Am Coulombwall 4a, 85748 Garching, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22422265" target="_blank"〉PubMed〈/a〉
    Keywords: Circular Dichroism ; DNA/*chemistry ; Gold/chemistry ; Metal Nanoparticles/*chemistry ; Microscopy, Electron, Transmission ; *Optical Processes
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 3
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2018-09-15
    Description: Highly efficient and widely applicable working mechanisms that allow nanomaterials and devices to respond to external stimuli with controlled mechanical motions could make far-reaching impact to reconfigurable, adaptive, and robotic nanodevices. We report an innovative mechanism that allows multifold reconfiguration of mechanical rotation of semiconductor nanoentities in electric ( E ) fields by visible light stimulation. When illuminated by light in the visible-to-infrared regime, the rotation speed of semiconductor Si nanowires in E -fields can instantly increase, decrease, and even reverse the orientation, depending on the intensity of the applied light and the AC E -field frequency. This multifold rotational reconfiguration is highly efficient, instant, and facile. Switching between different modes can be simply controlled by the light intensity at an AC frequency. We carry out experiments, theoretical analysis, and simulations to understand the underlying principle, which can be attributed to the optically tunable polarization of Si nanowires in an aqueous suspension and an external E -field. Finally, leveraging this newly discovered effect, we successfully differentiate semiconductor and metallic nanoentities in a noncontact and nondestructive manner. This research could inspire a new class of reconfigurable nanoelectromechanical and nanorobotic devices for optical sensing, communication, molecule release, detection, nanoparticle separation, and microfluidic automation.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
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  • 4
    Publication Date: 2013-09-07
    Description: An avian-origin human-infecting influenza (H7N9) virus was recently identified in China. We have evaluated the viral hemagglutinin (HA) receptor-binding properties of two human H7N9 isolates, A/Shanghai/1/2013 (SH-H7N9) (containing the avian-signature residue Gln(226)) and A/Anhui/1/2013 (AH-H7N9) (containing the mammalian-signature residue Leu(226)). We found that SH-H7N9 HA preferentially binds the avian receptor analog, whereas AH-H7N9 HA binds both avian and human receptor analogs. Furthermore, an AH-H7N9 mutant HA (Leu(226) --〉 Gln) was found to exhibit dual receptor-binding property, indicating that other amino acid substitutions contribute to the receptor-binding switch. The structures of SH-H7N9 HA, AH-H7N9 HA, and its mutant in complex with either avian or human receptor analogs show how AH-H7N9 can bind human receptors while still retaining the avian receptor-binding property.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shi, Yi -- Zhang, Wei -- Wang, Fei -- Qi, Jianxun -- Wu, Ying -- Song, Hao -- Gao, Feng -- Bi, Yuhai -- Zhang, Yanfang -- Fan, Zheng -- Qin, Chengfeng -- Sun, Honglei -- Liu, Jinhua -- Haywood, Joel -- Liu, Wenjun -- Gong, Weimin -- Wang, Dayan -- Shu, Yuelong -- Wang, Yu -- Yan, Jinghua -- Gao, George F -- New York, N.Y. -- Science. 2013 Oct 11;342(6155):243-7. doi: 10.1126/science.1242917. Epub 2013 Sep 5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Research Network of Immunity and Health, Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24009358" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Birds ; Crystallography, X-Ray ; Glycine/chemistry/genetics/metabolism ; Hemagglutinin Glycoproteins, Influenza Virus/*chemistry/metabolism ; Humans ; Influenza A virus/*metabolism ; Influenza in Birds/*virology ; Influenza, Human/*virology ; Protein Conformation ; Receptors, Cell Surface/*chemistry/genetics/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2018-06-06
    Description: In this work, we study the microwave field driven domain wall (DW) motion in an antiferromagnetic nanowire, using the numerical calculations based on a classical Heisenberg spin model with the biaxial magnetic anisotropy. We show that a proper combination of a static magnetic field plus an oscillating field perpendicular to the nanowire axis is sufficient to drive the DW propagation along the nanowire. More importantly, the drift velocity at the resonance frequency is comparable to that induced by temperature gradients, suggesting that microwave field can be a very promising tool to control DW motions in antiferromagnetic nanostructures. The dependences of resonance frequency and drift velocity on the static and oscillating fields, the axial anisotropy, and the damping constant are discussed in details. Furthermore, the optimal orientations of the field are also numerically determined and explained. This work provides useful information for the spin dynamics in antiferromagnetic...
    Electronic ISSN: 1367-2630
    Topics: Physics
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  • 6
    Publication Date: 2018-06-29
    Description: In this work, we study the microscopic dynamics of distorted skyrmions in strained chiral magnets (Shibatak et al 2015 Nat. Nanotechnol. 10 589) under gradient magnetic field and electric current by Landau–Lifshitz–Gilbert simulations of the anisotropic spin model. It is observed that the dynamical responses are also anisotropic, and the velocity of the distorted skyrmion is periodically dependent on the directions of the external stimuli. Furthermore, in addition to the uniform motion, our work also demonstrates an anti-phase harmonic vibration of the two skyrmions in nanostripes, and the frequencies can be effectively modulated by the anisotropic Dzyaloshinskii–Moriya interaction. The simulated results are well explained by Thiele’s theory, which may provide useful information in understanding the dynamics of the distorted skyrmions.
    Electronic ISSN: 1367-2630
    Topics: Physics
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  • 7
    Publication Date: 2018-06-09
    Description: Therapeutic resistance developed after chemotherapy and aggressive metastasis are the major causes of cancer-related death in patients with triple-negative breast cancer (TNBC). Survivin is the smallest member of the inhibitor-of-apoptosis proteins (IAPs) family, which plays critical roles in cell division and cell survival. High expression levels of survivin have been associated with therapeutic resistance in various cancers. We recently developed a novel small-molecule survivin inhibitor mimicking the IAP-binding motif of second mitochondria-derived activator of caspase, which showed high potency in promoting survivin degradation. Here, we show that survivin inhibitor MX106/MX107 suppresses TNBC cell proliferation. Moreover, MX106/MX107 synergized with chemotherapeutic drugs or radiation and significantly enhanced tumoricidal efficacy of genotoxic treatments. Mechanistically, MX106/MX107 induced degradation of XIAP and/or cIAP1, which inhibited nuclear factor B (NF- B) activation by genotoxic agents. Treatment with MX106/MX107 alone did not activate alternative NF- B signaling in breast cancer cells, which is likely attributable to their selective potency in degrading survivin in these cells. In addition, survivin degradation by MX106/MX107 dramatically increased abnormal mitotic spindle formation and cell division failure, which led to cell cycle arrest in breast cancer cells. Overall, our study suggests that combination treatment of TNBC using survivin inhibitors MX106/MX107 with cytotoxic chemotherapeutic drugs can achieve significantly improved therapeutic efficacy, which depends on MX106/MX107-mediated inhibition of genotoxic NF- B activation.
    Print ISSN: 0022-3565
    Electronic ISSN: 1521-0103
    Topics: Medicine
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  • 8
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS); 20160612-20160615; Frankfurt am Main; DOCMI.10.05 /20160608/
    Publication Date: 2016-06-17
    Keywords: glioma ; angiogenesis ; signaling ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 9
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS); 20160612-20160615; Frankfurt am Main; DOCP 036 /20160608/
    Publication Date: 2016-06-17
    Keywords: ras ; gliomagenesis ; signaling ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Chinese Astronomy and Astrophysics 15 (1991), S. 241-250 
    ISSN: 0275-1062
    Keywords: Quantum cosmology-inflationary universe
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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