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  • 1
    ISSN: 1420-9071
    Keywords: Key words. Intermediate filaments; assembly; polymorphism; fibrous proteins; scanning transmission electron microscopy (STEM) temperature sensitivity.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Intermediate filament (IF) proteins are encoded by a large multigene family and form polymers with a uniform diameter of approximately 10 nm. However, although the cytoplasmic representatives all confirm to a unit-type structural principle leading to the formation of extended coiled coils, it is becoming increasingly clear that subunit arrangements and physical properties vary among the different filaments. Thus, the intricate tissue-specific expression pattern of individual IF proteins (especially, their co-expression with other members of the IF protein family or with IF-associated proteins to form obligatory heteropolymers) points to distinct functions acquired during evolution relevant to cellular homeostasis in various tissues.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Keywords: Spinal cord; hemangioblastoma; surgery; outcome.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  This is a study on 19 patients, who underwent complete excision of an intramedullary hemangioblastoma of the spinal cord during the period 1984–1997. The study was conducted to evaluate their functional outcome. Some peculiarities of their clinical presentation and surgical treatment are discussed as well. There were 12 males and 7 females whose age ranged from 16 to 69 years. Five of 6 patients were affected by Lindau's disease had multiple intramedullary tumors. The length of their history averaged 22.6 months. While pain was the most common complaint at presentation, 12 out of 19 patients had progressive sensorimotor deficits. A total of 22 operation was performed. One patient underwent resection of a minute tumor residue a few months after the first operation. In 2 patients with multiple tumors a second tumor, which became clinically relevant, was resected 17 and 36 months after the first operation. There was no mortality. One patients developed a wound infection which required secondary closure. The functional status of the patients registered at discharge was worse in 22.7%, unchanged in 59.1%, and improved in 18.2% of the patients. At follow-up (6–142 months), the status of 9.1% of the patients was still worse, in 50% was unchanged and in 40.9% better than the preoperative one. All but one patients had complete postoperative pain relief. The data support the concept that radical excision of intramedullary hemangioblastomas can be achieved at low levels of surgical mortality and morbidity. Symptomatic patients should undergo surgery before they develop extensive sensorimotor deficits. In patients with multiple lesions, tumors distant from the symptomatic one should not be tackled.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The atmospheric pressure plasma jet (APPJ) [A. Schütze et al., IEEE Trans. Plasma Sci. 26, 1685 (1998)] is a nonthermal, high pressure, uniform glow plasma discharge that produces a high velocity effluent stream of highly reactive chemical species. The discharge operates on a feedstock gas (e.g., He/O2/H2O), which flows between an outer, grounded, cylindrical electrode and an inner, coaxial electrode powered at 13.56 MHz rf. While passing through the plasma, the feedgas becomes excited, dissociated or ionized by electron impact. Once the gas exits the discharge volume, ions and electrons are rapidly lost by recombination, but the fast-flowing effluent still contains neutral metastable species (e.g., O2*, He*) and radicals (e.g., O, OH). This reactive effluent has been shown to be an effective neutralizer of surrogates for anthrax spores and mustard blister agent. Unlike conventional wet decontamination methods, the plasma effluent does not cause corrosion and it does not destroy wiring, electronics, or most plastics, making it highly suitable for decontamination of sensitive equipment and interior spaces. Furthermore, the reactive species in the effluent rapidly degrade into harmless products leaving no lingering residue or harmful by-products. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Chaos 9 (1999), S. 673-681 
    ISSN: 1089-7682
    Source: AIP Digital Archive
    Topics: Physics
    Notes: When dissipative particles are left alone, their fluctuation energy decays due to collisional interactions, clusters build up and grow with time until the system size is reached. When the effective dissipation is strong enough, this may lead to the "inelastic collapse," i.e., the divergence of the collision frequency of some particles. The cluster growth is an interesting physical phenomenon, whereas the inelastic collapse is an intrinsic effect of the inelastic hard sphere (IHS) model used to study the cluster growth—involving only a negligible number of particles in the system. Here, we extend the IHS model by introducing an elastic contact energy and the related contact duration tc. This avoids the inelastic collapse and allows to examine the long-time behavior of the system. For a quantitative description of the cluster growth, we propose a burning-like algorithm in continuous space, that readily identifies all particles that belong to the same cluster. The criterion for this is here chosen to be only the particle distance. With this method we identify three regimes of behavior. First, for short times a homogeneous cooling state (HCS) exists, where a mean-field theory works nicely, and the clusters are tiny and grow very slowly. Second, at a certain time which depends on the system's properties, cluster growth starts and the clusters increase in size and mass until, in the third regime, the system size is reached and most of the particles are collected in one huge cluster. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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