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  • 1
    facet.materialart.
    facet.materialart.
    German Medical Science GMS Publishing House; Düsseldorf
    In:  Deutscher Kongress für Orthopädie und Unfallchirurgie; 72. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie, 94. Tagung der Deutschen Gesellschaft für Orthopädie und Orthopädische Chirurgie, 49. Tagung des Berufsverbandes der Fachärzte für Orthopädie; 20081022-20081025; Berlin; DOCPO17-404 /20081016/
    Publication Date: 2008-10-17
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 2
    facet.materialart.
    facet.materialart.
    German Medical Science; Düsseldorf, Köln
    In:  67. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie, 89. Tagung der Deutschen Gesellschaft für Orthopädie und Orthopädische Chirurgie und 44. Tagung des Berufsverbandes der Fachärzte für Orthopädie; 20031111-20031116; Berlin; DOC03dguA14-7 /20031111/
    Publication Date: 2003-11-11
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 3
    ISSN: 1432-1181
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The natural circulation loop DANTON at the Dresden University of Technology was designed to investigate the thermohydraulic properties of integrated reactor concepts with a natural circulation driven primary loop. It is not possible to reach a stable two-phase flow in the loop without passing flow instabilities. At an equilibrium of heating and cooling power the flow oscillations can exist at nearly constant frequencies and amplitudes. The oscillating mass flow signal had been investigated by various methods: (a) autocorrelation function, (b) Fast Fourier transformation, (c) estimation of a temporal Liapunov-exponent and (d) reconstruction of the system attractor in a three-dimensional phase space. The selected time-series express a non-linear behaviour, however, they are not chaotic. In comparison to the usual methods the applied analysing methods yield additional information about system frequencies, sensitiveness to disturbances and properties due to non-linear and chaotic behaviour in a natural circulation loop.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1433-0431
    Keywords: Schlüsselwörter Kniegelenk • Individualendoprothetik • Computerunterstütztes Operieren • Kinematische Optimierung • Minimal-invasives Vorgehen ; Keywords Knee joint • Custom-made endoprosthesis • Computer-aided surgery • Kinematic optimization • Minimal invasive procedure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract A new method is presented which allows the construction and implantation of highly precise custom-made endoprostheses for knee joints. The procedure is based on a computer-aided subtraction process of three-dimensional CT data. Using the differences of the CT scans, the endprosthetic components are modelled by means of a newly developed software package. The implants are manufactured by CNC machines and stereolithography. The method enables the surgeon to reduce bone resections and ensures an exact profile of the bone-implant interface. Incorrect positioning will be avoided and the implantation process can be performed more easily while the size of the operative approach will be minimized. Better postoperative kinematics and reduction of shearing effects will lead to better results in the long run. The procedure offers a series of new possibilities to optimize monocondylar and bicondylar knee joint endoprostheses.
    Notes: Zusammenfassung Es wird ein neuartiges Verfahren vorgestellt, das die Fertigung und Implantation von hochexakten individuell geformten Oberflächenprothesen am Kniegelenk ermöglicht. Die Vorgehensweise basiert auf einem computergestützten Subtraktionsprozess von CT-Volumendaten. Aus den Differenzen wird das Implantat als dreidimensionales (3D-) Objekt rechnerisch modelliert und über einen sterolithografischen Zwischenschritt mittels CNC-Fräsung bzw. gusstechnisch hergestellt. Durch das Verfahren wird nicht nur eine möglichst geringe und den individuellen Gegebenheiten angepasste Knochenresektion ermöglicht, sondern auch eine optimale Kontaktfläche zwischen der Prothesenkomponente und dem Knochen gewährleistet. Positionierungsfehler werden reduziert, gleichzeitig wird der Implantationsvorgang erleichtert und die Größe des notwendigen Operationszugangs erheblich verringert. Durch die bessere Kinematik und die Reduktion der Scherkräfte ist nicht nur eine bessere Funktionalität sondern auch eine längere Haltbarkeit zu erwarten. Das Verfahren bietet mannigfaltige Optionen zur Verbesserung der herkömmlichen monokondylären und bikondylären Kniegelenksendoprothetik.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We are interested in the thermal diffusion of a solitary wave in the anisotropic Heisenberg spin chain (HSC) with nearest-neighbor exchange interactions. The shape of the solitary wave is approximated by soliton solutions of the continuum HSC with on-site anisotropy, restricting ourselves to large width excitations. Temperature is simulated by white noise coupled to the system. The noise affects the shape and position of the solitary wave and produces magnons. Using implicit collective variables we describe the former effects and neglect magnons (i.e. we use the so-called adiabatic approximation). We derive stochastic equations of motion for the collective variables which we treat both analytically and numerically. Predictions for the mean values and the variances of the variables obtained from these equations are compared with the corresponding results from spin dynamics simulations. For the soliton position we find reasonable agreement between spin dynamics and the results of the collective variable treatment, whereas we observe deviations for the other collective variables. The stochastic dynamics of the position shows both a standard Brownian and a super-diffusive component. These results are analogous to results for the isotropic case, previously studied by some of the authors. In the present article we discuss in particular how the anisotropy enters the stochastic equations of motion and the quantitative changes it causes to the diffusion.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Allergy 58 (2003), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK; Malden, USA : Munksgaard International Publishers
    Contact dermatitis 53 (2005), S. 0 
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aloe vera has been used as a cosmetic and medical remedy since ancient times and has gained increasing popularity in recent years. Despite its widespread use, reports of allergic reactions are rare. We patch tested 702 consecutive patients with an oily extract from the leaves, Aloe pulvis from the entire plant and concentrated Aloe vera gel. A specially designed questionnaire was used for the use of Aloe vera, reasons and location of application, adverse reactions, occupation, hobbies and atopy. None of the subjects showed any reaction to one of the preparations. 2 components of the plant have to be distinguished: the bark of the leaves contains anthrachinones with pro-peristaltic and potential antibiotic and anticancer properties. Constraints have been imposed due to their considerable toxic potential. Today, mostly the Aloe gel from the center of the leaves is processed. It almost exclusively consists of carbohydrates to which also many medical effects have been attributed. Carbohydrates are not likely to induce contact sensitization, which might explain the outcome of our study. However, this does not justify unrestrained promotion of Aloe products, as scientific studies investigating the claims on its constitutional effects are few in number, and the majority of them have been unable to diminish the intuitive scepticism against miracle cures, like Aloe seems to be.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Melatonin regulates circadian and seasonal physiology via melatonin receptors expressed in the brain. However, little is known about the signal transduction mechanisms that mediate the action of melatonin in neuronal cells. To begin to address this issue, we expressed the human MT1 receptor in the human neuroblastoma SH-SY5Y cell line. In this cell line, melatonin acutely stimulated cAMP synthesis through a calcium-calmodulin dependent pathway. This stimulatory effect was independent of an interaction with Gi or Gs G proteins and dependent upon internal calcium stores. Melatonin also potentiated forskolin-activated cAMP synthesis. Differentiation of the neuroblastoma cells with retinoic acid to the neuronal phenotype did not alter the ability of melatonin to acutely stimulate cAMP. These data may be relevant to the neuronal action of melatonin and highlight the importance of the cellular context of expression of melatonin and other G protein-coupled receptors.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Sensitization of adenylate cyclase is a recently discovered phenomenon. Melatonin can induce a sensitized response of adenylate cyclase in ovine pars tuberalis cells where the receptor for melatonin is endogenously expressed. Although the mechanism is not fully understood, sensitization of adenylate cyclase may be an important part of the mechanism by which melatonin encodes daylength in the pars tuberalis of sheep and other animals. We used this as a hypothesis to search for a natural ligand that would activate adenylate cyclase in ovine pars tuberalis cells. The approach revealed pituitary adenylate cyclase activating polypeptide to be an indirect activator of adenylate cyclase in the ovine pars tuberalis. We discuss this in relation to the mechanism and importance of sensitization to the function to the pars tuberalis.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Copenhagen : Munksgaard International Publishers
    Allergy 55 (2000), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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