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  • 1
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  84. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie; 20130508-20130512; Nürnberg; DOC13hnod134 /20130415/
    Publication Date: 2013-04-16
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 2
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    facet.materialart.
    German Medical Science GMS Publishing House; Düsseldorf
    In:  65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20140511-20140514; Dresden; DOCMO.06.01 /20140513/
    Publication Date: 2014-05-14
    Keywords: deep brain stimulation ; essential tremor ; vim ; ddc: 610
    Language: English
    Type: conferenceObject
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  • 3
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  61. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) im Rahmen der Neurowoche 2010; 20100921-20100925; Mannheim; DOCV1670 /20100916/
    Publication Date: 2010-09-17
    Keywords: ddc: 610
    Language: English
    Type: conferenceObject
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  • 4
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  27. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII); 20130411-20130413; Heidelberg; DOC13dgii057 /20130405/
    Publication Date: 2013-04-06
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 5
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  A characteristic feature of the major histocompatibility complex (Mhc) polymorphism in mammals is the existence of allelic lineages shared by related species. This trans-species polymorphism has thus far been documented only in primates, rodents, and artiodactyls. In this communication we provide evidence that it also exists in cyprinid (bony) fishes at the class II A and B loci coding for the α and β polypeptide chains of the class II α : β heterodimers. The study has focused on three species of the family Cyprinidae, subfamily Rasborinae: the zebrafish (Danio rerio), the giant danio (D. malabaricus), and the pearl danio (D. albolineatus). The polymerase chain reaction was used to amplify and then sequence intron 1 and exon 2 of the class II B loci and exon 2 of the class II A loci in these species. Phylogenetic analysis of the sequences revealed the existence of allelic lineages whose divergence predates the divergence of the three species at both the A and B loci. The lineages at the B locus in particular are separated by large genetic distances. The polymorphism is concentrated in the peptide-binding region sites and is apparently maintained by balancing selection. Sharing of this unique Mhc feature by both bony fishes and mammals suggests that the main function of the Mhc (presentation of peptides to T lymphocytes) has not changed during the last 400 million years of its evolution.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  Cichlid fishes of the East African Rift Valley lakes constitute an important model of adaptive radiation. Explosive speciation in the Great Lakes, in some cases as recently as 12 400 years ago, generated large species flocks that have been the focus of evolutionary studies for some time. The studies have, however, been hampered by the paucity of biochemical markers for phylogenetic reconstruction. Here, we describe a set of markers which should help to alleviate this problem. They are the class I genes of the major histocompatibility complex. We provide evidence for the existence of at least 17 class I loci in cichlid fishes, and for extensive polymorphism of three of these loci. Since the polymorphism has a trans-species character, it will be possible to use it in investigating the founding events of the individual species. The sequences of the cichlid class I fishes support the monophyly of actinopterygian fish on the one hand, and of tetrapods on the other.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Immunogenetics 50 (1999), S. 116-123 
    ISSN: 1432-1211
    Keywords: Key words Histocompatibility ; Immunology ; Self-nonself discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Traditional as well as biotechnological processing of coal leads to complex mixtures of products. Besides chemical and physical characterization, which provides the information for product application, there is a need for bioassays to monitor properties that are probably toxic, mutagenic or cancerogenic. Investigations carried out focused on the selection, adaptation and validation of bioassays for the sensitive estimation of toxic effects. Organisms like bacteria, Daphnia magna and Scenedesmus subspicatus, representing different complexities in the biosphere, were selected as test systems for ecotoxicological and mutagenicity studies. The results obtained indicate that bioassays are, in principle, suitable tools for characterization and evaluation of coal-derived substances and bioconversion products. Using coal products, coal-relevant model compounds and bioconversion products, data for risk assessment are presented.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0630
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: 2 taken at low-temperature (4.2 K). This layered material is in a charge density wave (CDW) state below 35 K, with a period nearly commensurate to three times the atomic lattice. The CDW energy gap is 2Δ≈70 meV, but still the material remains metallic, even superconducting below 7.2 K. The bias-dependent phase shift in the STM image, in particular the comparison between occupied and unoccupied states, was shown to be attributable to the CDW, as no phase shift was observed in the atomic pattern. This phase shift does not result in a contrast reversal, which could be expected by analogy to some semi-conductor band gaps. The electron versus hole distribution has not been solved for a CDW gap, which is quite complex due to the many-band situation near the Fermi level. In the present work we write a general expression for the local density of states (LDOS) due to a commensurate CDW. Its amplitude and phase can be related in a simple way to the band structure, if one assumes an approximate form for the surface Bloch functions. We apply the method to the example of NbSe2, where its electronic structure is taken to be two-dimensional and the CDW is exactly commensurate to 3a. The new band structure and Fermi surface in the CDW state is calculated in perturbation theory, with a suitable pseudo-potential. The energy-dependent contrast is due to new states on the order of EF±Δ, having characteristic phases. The amplitude of the CDW is largest at the particular energies (or voltages) where tunneling occurs to the high symmetry points of the Brillouin zone. At these energies, the phase of the LDOS varies considerably, which gives a number of possible motifs in the STM image. For a shift in voltage corresponding to the energy gap edges, E=EF±Δ, we find that the maxima of the corrugation are shifted along the diagonal of the conventional unit cell.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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