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  • 1
    ISSN: 1432-1076
    Keywords: Key words Sacral dysgenesis ; Anal stenosis ; Currarino syndrome ; Chromosome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Most cases of sacral dysgenesis are considered to be sporadic events. We present two families in whom the presence of associated clinical features prompted specific investigation of chromosome 7, leading to the identification of an underlying chromosome 7q deletion causing sacral dysgenesis. All affected individuals had microcephaly and developmental delay. Detailed cytogenetic studies confirmed that all three affected individuals had a deletion of chromosome 7q associated with their sacral dysgenesis, developmental delay and related problems. The three affected patients were studied clinically, radiologically and cytogenetically. Eleven unaffected individuals from the two families were also investigated by genetic studies, specifically evaluating chromosome 7. Conclusion It is important that detailed family history, evaluation of associated malformations and the overall clinical picture be considered in identifying the underlying diagnosis in cases of anal stenosis/sacral agenesis. The cases we present demonstrate the value of detailed chromosome studies in such situations.
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  • 2
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Farbkodierte Duplex-Sonographie ; Fibromuskuläre Dysplasie ; intimale Variante ; A. carotis ; Key words Ultrasonography ; -doppler ; -color ; Fibromuscular-dysplasia-diagnosis ; Carotid-artery-diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Traditionally, intra-vitam diagnosis of fibromuscular dysplasia (FMD) of brain supplying arteries is a domain of conventional selective angiography. We are aware of only two publications reporting of ultrasound displayed intimal and medial variants of carotid artery FMD, in one case each. We present a patient in whom color-coded duplex-sonography revealed a web-like carotid artery bulb stenosis meeting the specific criteria of a subtype of intimal FMD.
    Notes: Zusammenfassung Die intra vitam Diagnose der fibromuskulären Dysplasie (FMD) hirnversorgender Arterien gilt als eine Domänie der selektiven Katheterangiographie. Bislang liegen nur zwei Mitteilungen über die Diagnose der FMD durch B-Bild- beziehungsweise Duplex-Sonographie der A. carotis vor, eine davon mit Darstellung eines membranösen intimalen Subtyps der FMD. Wir konnten bei einem Patienten die spezifischen Kriterien einer septalen intimalen FMD des Bulbus caroticus Duplex-sonographisch dokumentieren.
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  • 3
    ISSN: 1433-0423
    Keywords: Schlüsselwörter Ultraschallbiomikroskopie ; Kataraktchirurgie ; Hinterkammerlinsen ; Key words Ultrasound-biomicroscopy ; Cataract-surgery ; Posterior-chamber-lenses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Correct positioning of transscleral haptics for sulcus fixation of IOL haptics may be difficult due to lack of visual control by the surgeon. We determined the haptic sites in eyes which underwent secondary IOL implantation with transscleral suturing using ultrasound biomicroscopy (UBM) (Humphrey Instruments, Inc., San Leandro, CA, USA). Eighteen eyes of 17 patients were included in the study. The follow-up time ranged from 1 to 36 months (mean: 7 months). The positions of 36 IOL-haptics were documented by UBM examination. Twelve haptics (33%) were found in the sulcus, whereas 18 haptics (50%) were located posteriorly to the sulcus. Six haptics (17%) were identified anteriorly to the sulcus. There were no complications resulting from dislocation. In one of the eyes, suture infection occurred requiring surgical revision and antibiotic therapy.
    Notes: Die korrekte Positionierung der Linsenhaptiken bei transskleraler Nahtfixierung ist schwierig, da sich die Nahtführung im Sulcus ciliaris und hinter der Iris der Beobachtung durch den Operateur entzieht. Wir haben 17 Patienten (18 Augen) nach transskleraler Haptikfixierung mit dem Humphrey-Ultrasound-Biomicroscope (UBM) (Humphrey Instruments, San Leandro, CA, USA) untersucht. Die Nachbeobachtungszeit betrug zwischen 1 und 36 Monaten (Mittel: 7 Monate). Neben der Haptikposition wurde der intraokulare Druck registriert. 12 von 36 Haptiken (33%) waren im Sulcus ciliaris lokalisiert. 18 Haptiken (50%) wurden hinter dem Sulkus gefunden. Anteriore Lokalisationen (hintere Iriswurzel) wiesen 6 Haptiken (17%) auf. Komplikationen , die aus diesen Fehlpositionierungen resultieren könnten, sahen wir nicht. In einem Fall trat eine infektiöse Infiltration des Stichkanals auf, die eine operative Revision und systemische Antibiotikagabe notwendig machte.
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  • 4
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Langmuir 11 (1995), S. 4593-4595 
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-7357
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Low temperature upper critical field studies have been carried out in a new organic superconductor β″-(BEDT-TTF) 2 SF 5 CH 2 CF 2 SO 3. For field parallel to the superconducting layers, the upper critical field determined from transport measurements exceeds the BCS Pauli limit at low temperatures. The angular dependence of the resistive transition shows that the upper critical field can be best described by a quasi-two-dimensional model with a cusp near the field parallel to the plane direction.
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  • 7
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 73 (1998), S. 2524-2526 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A thin semiconducting NiO film is exposed to NO2 at room temperature. This exposure causes a work function change at the surface of the film due to adsorption of the NO2 molecules. It is found that there is a strong dependence of the adsorptivity, i.e., the amount of work function change per unit time, on the magnitude of an electrical field that is applied perpendicular to the film surface. This induced adsorptivity change is known as the electroadsorptive effect. In order to modulate the adsorptivity significantly, the electrical field strength must exceed 104 V/cm. This requirement can be achieved by using hybrid suspended gate field effect transistors with an air gap height below 1 μm. © 1998 American Institute of Physics.
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  • 8
    Electronic Resource
    Electronic Resource
    Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Science Inc.
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Whether the size of a retroperitoneal lymph node reflects its status is not clear. We measured the size of 125 positive and 160 negative pelvic lymph nodes in 32 consecutive patients with node-positive endometrial cancer. The measurements were compared with those of 143 pelvic lymph nodes of five randomly selected patients with endometrial cancer without node involvement. Overall, positive lymph nodes were larger than negative lymph nodes in both node-positive patients and node- negative controls (P 〈 0.01). There was a positive correlation between the size of positive lymph nodes and the size of the metastasis therein (P 〈 0.01). However, 68 of 125 (54%) positive lymph nodes measured less than 10 mm in maximum diameter, while 46 of 160 (29%) negative lymph nodes in node-positive patients measured more than 10 mm in maximum diameter. The metastasis was detected in more than 50% of step-serial sections in only 74% of positive lymph nodes. These data suggest that the size of a lymph node does not reliably reflect its status. Thus, these nodes may be missed if only enlarged nodes are removed. If only one section of a lymph node is performed, at least 26% of metastases will be missed.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Der Internist 39 (1998), S. 623-643 
    ISSN: 1432-1289
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
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  • 10
    ISSN: 1432-2102
    Keywords: Schlüsselwörter CTA ; Spiral-CT ; Dissektion ; ACI ; Key words CT angiography ; Spiral CT ; Dissection ; ICA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: To evaluate the role of CT angiography (CTA) in the diagnosis of dissection of the internal carotid artery (ICA). Methods: In 21 patients who were clinically or sonographically suspected of having a dissection of the ICA, we performed CTA covering the extracranial course of the ICA. Our technique included spiral scanning (Picker PQ 2000), slice thickness 3 mm, index 1.5 mm, pitch factor 1.25, tube voltage 130 kV, amperage 125 mA, i. v. bolus injection of 100 ml nonionic contrast medium, injection rate 4 ml/s and scan delay 15 s. Spiral data were processed using a workstation (Picker Voxel Q) to calculate 3D “angiographic” reconstructions, maximal intensity projections and multiplanar reconstructions. In 20 of the 21 patients transfemoral angiography was performed, and in all patients cw-Doppler ultrasonography of the carotid arteries was performed. Results: Sensitivity of CTA in acute extracranial dissection of the ICA was 100 % (14/14). One patient had a pseudoaneurysm of the ICA, two patients had excessive kinking and one patient showed an atheromatous carotid ulcer. DSA could confirm this in all cases. One intracranial ICA dissection, not covered by the scan field, was missed by CTA. CTA source images demonstrated mural thickening and eccentric luminal narrowing in cases of dissection. 3D reconstructions showed tapering of the ICA. Conclusion: CTA is a reliable tool in the diagnosis of ICA dissection. Further studies comparing CTA, MRI and duplex ultrasound are necessary.
    Notes: Zusammenfassung Ziel der vorliegenden Studie war es, den Stellenwert der CT-Angiographie (CTA) bei der Diagnose von Dissektionen der A. carotis interna (ACI) zu ermitteln. Die Befunde der CTA wurden mit Ergebnissen der digitalen Subtraktionsangiographie (DSA) und der cw-Dopplersonographie (cw-DS) verglichen. Wir untersuchten 21 Patienten mit klinischem oder dopplersonographischem Verdacht auf eine ACI-Dissektion. Bei akuter extrakranieller ACI-Dissektion war die Sensitivität der CTA 100 % (14/14). Eine intrakranielle ACI-Dissektion wurde durch die CTA nicht erfaßt, da sie außerhalb des Scanbereichs lag. Die in der cw-DS unspezifischen pathologischen Befunde konnten mit der CTA geklärt werden. Häufigster Befund in der CTA war eine exzentrische Lumeneinengung und Wandverdickung sowie eine spitzauslaufende Verschmächtigung (sog. tapering) in der dreidimensionalen (3D-) Rekonstruktion. Die CTA ist bei akuter extrakranieller Karotisdissektion eine verläßliche und wenig invasive Untersuchungsmethode. Vergleichende Studien mit CTA, Duplexsonographie und Magnetresonanztomographie (MRT) sollten noch durchgeführt werden.
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