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  • 1
    Unknown
    Edinburgh : Churchill Livingstone
    (Systemic pathology, v. 7)  
    Call number: QZ4:35/7(3)
    Keywords: Lymphatics / Diseases ; Thymus / Diseases ; Lymph nodes / Diseases ; Spleen / Diseases ; Lymph Nodes / immunology ; Lymphatic Diseases ; Spleen / immunology ; Thymus Gland / immunology ; Lymphoma / pathology
    Notes: 2nd edition has title: Systemic pathology. Thymus, lymph nodes, spleen, and lymphatics.
    Pages: 1042 p. : ill. (some col.)
    Edition: 3rd ed.
    ISBN: 044303429X
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  • 2
    ISSN: 1432-1246
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Die Autoren vollzogen an Kaninchen mit akuter Quecksilbervergiftung Untersuchungen des Eiweißspektrums, der Muco- und Lipoproteide Bowie der Aktivität der alkalischen Serumphosphatase. Gleichzeitig führten sie in vitro-Teste durch, um den Mechanismus zu klären, der zur Inaktivierung der Phosphatase führt. Die Ergebnisse zeigen, daß lösliche Quecksilbersalze, ix. injiziert, eine Verminderung des Gesamteiweißes verursachen, und zwar hauptsächlich der Albumine bei gleichzeitigem Anstieg der β-Globulin-Fraktion. Es wurde eine deutliche Hebung des Mucoproteidspiegels im Blutserum beobachtet. Das Lipoproteidbild des Serums zeigee eine charakteristische Abnahme der kleinmolekularen Fraktion α zugunsten der großmolekularen Fraktionen β and γ. Quecksilber-Ionen verursachen Aktivitätsabfall der alkalischen Phosphatase durch direkte Einwirkung auf das Enzym. Die Phosphataseaktivität verhält sich umgekehrt proportional zur Hg-Ionen Konzentration. Die Inaktivierung erfolgt wahrscheinlich durch Blockierung der Amino- und Carboxylgruppen des Enzymeiweißes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 54 (1992), S. 307-308 
    ISSN: 1432-0649
    Keywords: 42.55 ; 42.60
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract For the He-Ne/I2-laser, a stable monomode operation has been realized when the tube pressure exceeds a certain level. An output power of more than 1 mW has been obtained at the 632.8 nm laser transition. Within the monomode tuning range of the laser, the d, e, f, g, and h, i, j iodine hyperfine components of the R(127) line of the 11–5 band of the B 3 II + 0u−X 1Σ+ 0g electronic transition have been observed. The mode selection method used makes it possible to increase the contrast of the iodine hyperfine components.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The sorption behavior of microamounts of Hf and Ta on DOWEX 50×8 and DOWEX 1×8 from aqueous HCl/HF solutions has been investigated. Suitable separation conditions for these two elements on cation exchange resins were found in solutions containing 1.5M HCl/10−4M HF and 0.05M HCl/10−3M HF. Kinetic experiments showed that the system can be applied in high speed on-line separations.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-6079
    Keywords: 36.40.+d ; 34.50.−s ; 35.20.Gs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The stability of gold cluster ions Au n + (2≦n≦23) has been investigated via collision induced dissociation in a Penning trap. Threshold energies and dissociation channels have been determined. The cluster stability exhibits a pronounced odd — even alternation: Clusters with an odd number of atoms,n, are more stable than the even-numbered ones. Enhanced stabilities are found for Au 3 + , Au 9 + , and Au 19 + in accordance with the Clemenger-Nilsson and the deformed jellium model of delocalized valence electrons. Excited odd cluster ions withn≦15 predominantly decay by evaporation of dimers; all others decay by monomer evaporation. From the dissociation channels estimates of the binding energies are deduced.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The collision-induced dissociation of positively charged gold clusters (2-23 atoms) stored in a Penning trap has been studied. After collisions with rare gases, excited clusters predominantly decay by emission of one or two atoms. The loss of two atoms occurs most probably through the emission of a dimer rather than by a sequential evaporation. The minimum kinetic energies of clusters required to induce dissociation exhibit a pronounced odd-even effect. Clusters with an even number of delocalized electrons are more stable than those with an odd number.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Haemophilus influenzae represents a common cause of human disease and an important source of morbidity and mortality. Disease caused by this organism begins with colonization of the upper respiratory tract. Several studies indicate that H. influenzae is capable of binding to and entering cultured human cells, properties which are potentially of relevance to the process of colonization. In the present study, we isolated an H. influenzae gene designated hap, which is associated with the capacity for In vitro attachment and entry. Analysis of the derived amino acid sequence of hap demonstrated significant homology with the serine-type lgA1 proteases expressed by H. influenzae and Neisseria gonorrhoeae. It is notable that the hap product shares the catalytic domain of the lgA1 proteases and appears to be processed and secreted in an analogous manner. We speculate that the hap gene product is an important determinant of colonization, perhaps enabling the organism to evade the local immune response and thereby persist within the respiratory tract.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Escherichia coli induces the expression of more than 50 proteins in response to starvation for a carbon source. Strains MC7 (csi7::phoA) and MC19 (csi19::phoA) contain fusions of a signal peptide-deficient phoA reporter sequence to a csi (carbon starvation-inducible) gene. PhoA expression increased when these strains were deprived of a carbon source or entered stationary phase but did not when the cells were deprived of a nitrogen source or subjected to osmotic, oxidative or thermal stress. Mapping and sequence analysis of the cloned phoA fusions in strains MC7 and MC19 indicated that they had occurred in different locations within the same previously unidentified gene. The wild-type allele of this gene was cloned and the encoded protein was found to be a new lipoprotein. Therefore we propose to call this locus slp (starvation lipoprotein). The 22 kDa Slp protein is associated with the outer membrane fraction. The slp gene was located at 78.6 centisomes on the E. coli genetic map. The -10 and -35 regions upstream of the mRNA start site were characteristic of a σ70 promoter. The major transcript from this promoter was sufficiently large to contain slp sequences but not the downstream open reading frame. Induction of β-galactosidase activity from a slp::lacZ translational fusion during carbon starvation or stationary phase was independent of cAMP, RpoS (KatF) and DnaK, all of which are known to affect the expression of certain starvation-inducible or stationary phase-inducible proteins.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0983
    Keywords: Metarhizium anisopliae ; Metarhizium flavoviride ; Beauveria bassiana ; Polymerase chain reaction ; Polymorphism ; RAPD markers ; Entomopathogenic fungi ; Acrididae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Polymerase chain reaction (PCR)-based technology, involving random amplification of polymorphic DNA (RAPD), was used to assess the genomic variability between 24 isolates of deuteromycetous fungi (Metarhizium anisopliae, Metarhizium flavoviride, unidentified strains of Metarhizium and Beauveria bassiana) which were found to infect grasshoppers or locusts. M. flavoviride showed little intraspecific variability in PCR-amplified fragments when compared to M. anisopliae. The high level of variability in PCR-amplified fragments contained within M. anisopliae was similar to the total variability between B. bassiana, M. anisopliae and M. flavoviride, and suggests that M. anisopliae may include a number of cryptic species. Four polymorphic RAPD fragments were used to probe the genomic DNA of the various species and strains. On the basis of these probes the fungi can be grouped into M. flavoviride, M. anisopliae, or B. bassiana. According to PCR-amplified fragments, previously-unidentified Metarhizium strains were characterized as M. flavoviride. There was little evidence that these fungi, all isolated from, or virulent towards, grasshoppers or locusts, showed host-selection in PCR-amplified fragments. Nor was geographical origin a criterion for commonalty based on PCR-amplified fragments. PCR-fragment-pattern polymorphisms and the construction of probes from one or more of these fragments may provide a useful and rapid tool for identifying species and strains of entomopathogenic fungi.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0983
    Keywords: Pythium ultimum ; Outcrossing ; Random amplified polymorphic DNA (RAPD) ; Restriction fragment length polymorphisms (RFLPs)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The oomycete Pythium ultimum is homothallic, thus a single isolate completes the sexual stage in pure culture. It has been generally assumed that homothallic oomycetes are predominantly inbreeding. In P. ultimum, antheridia occasionally develop from hyphae not directly connected to the oogonium and appear to participate in fertilization, suggesting a possible mechanism for outcrossing. We have used molecular markers to confirm that outcrossing can occur between isolates of P. ultimum. Genetic markers based on randomly amplified polymorphic DNA (RAPD) and restriction fragment length polymorphisms (RFLP) were used to distinguish isolates in a collection of P. ultimum. Two isolates displaying a high level of polymorphism were mixed and placed on media which allows the development of the sexual stage. RAPD markers were used to screen single oospore progeny to identify potential hybrids between the two parental isolates. Subsequent self-fertilization of one putative F1 yielded a F2 population which demonstrated segregation and independent assortment of RAPD and RFLP markers. A similar strategy was used to show that an isolate which is incapable of producing oospores in pure culture can outcross when mixed with a homothallic isolate. These results suggest that other homothallic oomycetes may be capable of outcrossing, and sexual reproduction may, therefore, play an important role in the generation of variation in homothallic oomycetes.
    Type of Medium: Electronic Resource
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