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  • 1
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A low-temperature anomalous magnetoresistance has previously been reported in disordered ultrathin DyBa2Cu3O7−x films. This unusual behavior was associated with interactions between the charge carriers and a magnetic lattice. Here, new results are presented showing a peak in the temperature dependence of the resistivity near the Dy3+ Néel temperature. A calculation is included which shows that the peak in R(T) is consistent with spin disorder scattering from the Dy3+ ions as they order antiferromagnetically. These observations lend support to the suggestion, based on neutron scattering studies, that the Dy3+ interactions are not strictly dipolar and that the electrons may contribute to the magnetic ordering of the Dy3+ sublattice.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-7446
    Keywords: channel catfish ; fenbendazole ; metabolism ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fenbendazole (FBZ) was administered intravenously (1 mg/kg) and orally (5 mg/kg) to catheterized, confined channel catfish. Blood samples were collected for 72 h, and resulting FBZ plasma concentrations were pharmacokinetically modelled. Following intravenous administration t1/2α was 0.51 h, t1/2β was 16.8 h, body clearance (C1b) was 0.0598 L/kg/h, and Vd (area) was 1.45 L/kg. After oral administration the t1/2 (abs) was 1.47 h, the t1/2β was 20.1 h, and the tlag was 0.1 h. Following oral administration of 5 mg FBZ/kg body weight, the following tissues and body fluids were sampled for concentrations of FBZ, oxfendazole (FBZ-SO), sulphone metabolite (FBZ-SO2) and hydroxy metabolite (FBZ-OH): liver, posterior kidney, fat, muscle, bowel contents and urine. Fenbendazole was detected in the highest concentrations in abdominal fat, whereas oxfendazole was found primarily in the kidney, liver and abdominal fat. The sulphone metabolite was detected only in urine and bowel contents, while the hydroxy metabolite was found most often in the liver and abdominal fat samples.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1440
    Keywords: Acyl-neuramic acids ; Plasma ; T-lymphocyte ; Mammary carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Increased sialic acid levels reflecting tumor burden are found on the surface of T-lymphocytes and in the plasma of patients with carcinoma of the mammary gland. The data of the determinations of sialic acid content and distribution on T-cells, using microanalytical methods such as HPLC and a colorimetric test, show that the total sialic acid content is increased by about 60% and that nearly 80–90% of the sialic acids consist of Nacetyl-9-O-acetyl-neuraminic acid, in comparison to the healthy controls (not containing O-acetylated neuraminic acid). Investigations on lymphocytes of malignant melanoma patients show similar changes of sialic acid content and distribution on the cell surface. Increased sialic acid levels are also found in the plasma of patients with cancer but no O-acetylated derivative can be found. Furthermore the examinations show that the separation of the T-lymphocytes from the total lymphocyte fraction is not required. Determination of sialic acids in the total lymphocyte fraction can be a simplification in carrying out further diagnostic investigations. A high level of sialic acids as “antirecognition factor” seems to be not only a marker of tumor cells but also an attribute of T-lymphocytes, involved in the defence against the malignoma (malignant melanoma, breast cancer). Considering the possible contribution of sialic acid to the immunoregulatory protective mechanism during the first stage of pregnancy, sialic acid content and distribution on T-cells of pregnant women are investigated. Both an increase and a change in the distribution of sialic acids can be excluded.
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  • 5
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: For condensed benzene ice layers, core photoabsorption near edge structure (x-ray absorption; recorded by Auger electron yield measurements), decay electron spectra for resonant and nonresonant excitation, and fragmentation as evident in yields of hydrogen and other ions, have been measured in the C1s region. The absorption spectrum is better resolved than most previously published spectra, exhibits some new features, and shows a high degree of parallelity to the spectrum of isolated molecules. Interestingly, the hydrogen ion yield indicates a particular dissociativeness of a certain core excitation resonance, X, which in the molecule has previously been assigned to a Rydberg state. This selective dissociation suggests that the responsible excitation is strongly antibonding for the carbon–hydrogen bond, while the degenerate Rydberg states broaden into a conduction band in the solid; and that the bond breaking probably occurs or at least starts in the core-excited state, thus proceeding on an extremely short time scale, similarly to observations for other hydrogen-containing molecules. The decay spectra are analyzed in terms of autoionization vs normal Auger decay and indicate that, apart from the first strong π resonance (which leads to pure autoionization) and the X resonance, the core resonances partly or fully ionize before core decay takes place. For the X resonance, the decay spectrum contains a contribution which cannot be assigned to intact benzene; this is taken as additional evidence for ultrafast dissociation, i.e., competitive with core decay. We use these results for a discussion of the influence of condensation on excitation, decay, and fragmentation.
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