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  • 1
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'hémophilie et la maladie de Willebrand représentent les affections congénitales les plus fréquentes caractérisées par des troubles du saignement et de la coagulation. La situation des malades atteints de ces affections s'est modifiée considérablement au cours des 2 ou 3 dernières années. Le propos de cet article est de faire le point sur la démographie et la mortalité de l'hémophilie puis, ensuite, de passer en revue les problèmes thérapeutiques de base posés par l'hémophilie et la maladie de Willebrand lors de la chirurgie en insistant sur l'emploi des constituants sanguins.
    Abstract: Resumen La hemofilia y la enfermedad de von Willebrand son las alteraciones congénitas de la coagulación de mayor incidencia. La situacion de estos pacientes ha cambiado en forma drástica en las últimas 2 a 3 décadas. El propósito de este artículo es, primero, suministrar cifras demográficas y de mortalidad en la hemofilia y, luego, revisar los problemas de tratamiento, especialmente en relación a la cirugía en la hemofilia y en la enfermedad de von Willebrand con énfasis en el uso de componentes sanguíneos. Actualmente, el riesgo mayor en los hemofílicos candidatos a un procedimiento operatorio no es el procedimiento quirúrgico de por sí. Los problemas de hemostasis en pacientes carentes de inhibidores pueden ser manejados en forma casi totalmente rutinaria. Es el problema de la terapia de sustitución el que constituye una amenaza, por el riesgo de hepatitis e infección por HTLV-III. La solución puede ser hallada en la tecnología genética. Hoy se conocen los códigos genéticos para los factores IX y VIII. Esto presenta el primer paso hacia la producción de concentrados “estériles” de factores capaces de remediar los efectos colaterales del uso de componentes sanguíneos en el tratamiento de desórdenes congénitos de la coagulación.
    Notes: Abstract Hemophilia and von Willebrand's disease are the most common congenital coagulation and bleeding disorders. The situation for patients suffering from these conditions has changed drastically during the last 2 to 3 decades. It is the purpose of this article, first, to give data on demography and mortality in hemophilia and, then, to review basic problems of therapy, especially in connection with surgery in hemophilia and von Willebrand's disease with emphasis on the use of blood components.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1279-8517
    Keywords: Endoscopic photography ; Larynx ; Pharynx
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'amélioration de la qualité des films et la possibilité d'utiliser un système de conduction de la lumière plutôt que des fibres optiques permettent de faire des photographies endoscopiques du larynx et du naso-pharynx en utilisant la même puissance lumineuse que pendant un examen clinique de ces régions. La possibilité d'un examen endoscopique peut souvent contribuer à clarifier les aspects confus de nombreuses lésions volumineuses qui modifient l'anatomie sur les images obtenues en tomodensitométrie et en résonance magnétique nucléaire. La photographie endoscopique devient de ce fait un excellent instrument d'enseignement.
    Notes: Summary Improvements in photographic film and the availability of fluid light transmitters rather than fibrooptics permit endolaryngeal and nasopharyngeal photography to be conducted using the same light levels as simple diagnostic examinations of these areas. The added perspective of endoscopic examination can often clarify many confusin bulky lesions that distort CT and MR anatomy. Thus endoscopic photography is a tremendous teaching tool.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1939
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Leaf chemistry of a willow clone (Salix aquatica Smith) differed significantly when grown at constant relative growth rates depending upon the relative availability of nutrients and light. Concentration of amino acids and nitrate were high in plants grown with a relative surplus of nutrients. Concentrations of starch, tannin, and lignin, on the other hand, were high in plants grown with a relative surplus of carbon. Photosynthetic rates, expressed per unit leaf area, were similar when plants were grown under high light conditions, regardless of nutrient availability. Dark respiration was much higher in plants supplied with abundant nutrients than in those with a more limited supply, reflecting differences in nitrogen concentration of the tissue. The experimental approach allows plants to be grown to a standard size with differing, but highly uniform chemistry. Plants grown in such a manner may provide good experimental material to evaluate interactions between herbivores or pathogens and their hosts.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    X-Ray Spectrometry 18 (1989), S. 109-112 
    ISSN: 0049-8246
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: By using the total reflecting properties of x-rays inside glass capillary tubes, intense fine or microbeams of x-rays can be obtained. In combination with conventional diffraction x-ray tubes, microbeams with a diameter of a few micrometres and with an intensity sufficient for trace element analysis can be achieved. The basic physics behind the capillary technique is reviewed and an energy-dispersive x-ray fluorescence microbeam spectrometer for trace element analysis is described. Examples of applications of the microbeam spectrometer are given and the future perspectives of the capillary technique are discussed.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-6903
    Keywords: GABA ; GABA-T ; microelectrophoresis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The reduction to the micro-scale of a recently described electrophoretic method for the evaluation of GABA catabolism by GABA-T is presented. The micromethod involves the electrophoresis, in 1 mm diam. capillaries, of small samples of mixtures of [14C]GABA and its metabolites. By coupling this procedure to previously devised micromethods, it was possible to evaluate GABA-T attack to14C labeled GABA diffusing across a single microdissected neuronal membrane.
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  • 6
    ISSN: 1432-198X
    Keywords: Na−K transport ; Proximal tubule ontogeny ; Primary cell culture ; Terminal differentiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There are several lines of indirect evidence suggesting that the renal tubule cells have not yet reached terminal differentiation at birth. Methods used in cell biology can now be applied to study renal ontogeny. This review describes how primary cultures of proximal tubule cells from rats can be used to investigate developmental changes in Na permeability and Na-K-ATPase-mediated transport.
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  • 7
    ISSN: 1432-1920
    Keywords: Isotope cisternography ; Technetium-DTPA ; Computed tomography ; Healthy volunteers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Radiological assessments of patients with symptoms of impaired cerebrospinal fluid (CSF) circulation are usually based on observations of anatomical and functional alterations using computed tomography (CT) and radionuclide cisternography (RC). In order to define criteria of normality for these two techniques, 30 healthy volunteers have been studied. In the studies of CSF flow the radiopharmaceutical 99mTc-DTPA was used and single photon emission computed tomography (SPECT) was performed as a complement to planar scintigraphy. In 16 of the 30 volunteers the pattern of CSF flow was normal according to conventional criteria. In these subjects the radioactivity was symmetrically located over the parietal cortex 24 h after the injection and no intraventricular activity could be recorded. In 11 (41%) of the subjects, radioactivity could be observed in the lateral ventricles 6 h after injection. One of these subjects had a reflux of radioactivity into the lateral ventricles. The intraventricular radioactivity persisted for at least 24 h. This subject also had signs of obstruction of CSF flow over the convexities. Asymmetric distribution of radioactivity within the CSF spaces was observed in the images obtained after 6 but not 24 h in two cases. One of those also demonstrated transient intraventricular radioactivity. The results of the computed tomography were interpreted to be normal in 19 (63%) of the 30 volunteers. One subject had an asymmetric ventricular system. The CT scans of six subjects (20%) differed considerably from the others as they displayed wide cortical or vermian sulci at the borderline of normal variations. The case with the pathological RC belonged to the group of subjects who had wide sulci. He also had a wide third ventricle. No subject had dilated lateral ventricles on CT. It is concluded that transient but not persistent (up to 24 h) intraventricular reflux should be interpreted as a normal finding in radionuclide cisternography. The probable mechanism for this reflux is discussed.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1572-9702
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The phoridMegaselia halterata (Wood) was found to carry significantly moreBrennandania lambi (Kerzal) than the sciaridLycoriella mali (Fitch) in samples collected from six mushroom farms.B. lambi was attached to both the phorids and mainly between the procoxae and mesosternum (57&) and between metacoxae and the first abdominal sternite (36%).B. lambi detached fromM. halterata only in the presence ofAgaricus mycelium. Evidence for dispersal ofB. lambi byL. mali andM. halterata is presented and the role of phoresy in the dispersal ofB. lambi is discussed.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 130 (1987), S. 187-192 
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The AM Her type system E1405-451 is known to show 1–3 second variability in its optical emission. Our observations show this variability to be due to quasi-periodic oscillations with a coherence time on the order of one minute. The observations also reveal variations in the color of the oscillating light source. These variations are difficult to explain with present cyclotron emission models.
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