Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-1041
    Keywords: Rauwolfia derivatives ; breast cancer ; multicentre study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Studies reporting a suspected association between breast cancer and rauwolfia derivatives were first published in 1974 and more recent studies have produced conflicting results. A further study is described in which groups of investigators from Aberdeen, Dundee and London attempted to ascertain the previous exposure to rauwolfia derivatives of female patients discharged from hospital with a confirmed diagnosis of breast cancer. Their exposure as recorded in the hospital and general practitioners' records was compared with that in two control groups, matched by general practitioner, age, year of admission to hospital and marital state, the first comprising patients with a cancer other than breast cancer and the second, patients with a non-malignant disorder. For patients with breast cancer compared with those with a non-malignant disorder the overall estimate of the relative risk of breast cancer in patients exposed to rauwolfia derivatives is 0.94 (95 patients exposed). The occurrence of hypertension and use of hypotensive agents and prolactin stimulators was also noted. Possible sources of bias were examined and none appeared to be significant. The problems created by the multicentre approach are also discussed.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A woman is described who has a severe bone dysplasia confined to the limbs. The degree of involvement is more marked in the distal bones. Her forearms and legs are short; the fibulae are represented by distal triangular remnants; the metacarpals are short, several phalanges in the fingers are absent; and the toes are represented by “ball-like” remnants containing a single bone. The findings in our patient are compared to previously reported cases of acromesomelic dwarfism.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Two cases of trisomy 12p due to a familial translocation t(12;21) (p11;p11) inherited through three generations are presented. The clinical features of both affected individuals are consistent with those previously reported. Study of the NORs by silver staining showed translocation of the NOR from chromosome 21 onto the der(12) and suggested that the activity of this site has been suppressed in some carriers.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary This paper describes two families in which four boys and two girls were affected with geroderma osteodysplastica. The major features of this syndrome include a droopy, jowly, prematurely aged appearance that has been likened by previous authors to the dwarfs in Walt Disney's ‘Snow White.’ Also, their skin lacks normal elastic recoil. The bones are osteoporotic and susceptible to fractures, particularly the vertebrae, which show compression with anterior wedging and biconcavity. The findings in the present families are compared with those in the originally reported family. There was a high degree of consanguinity between the parents in both of the present families and the previous hypothesis of X-linked inheritance is questioned.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Dans la chirurgie carotidienne, le succès dépend de la sélection des cas, de l'attention aux détails de l'intervention, d'une protection adéquate du cerveau pendant le clampage de la carotide. Diverses méthodes ont été proposées pour vérifier, pendant le clampage, l'efficacité de la circulation collatérale. Elles sont peu pratiques et n'offrent pas toute garantie de sécurité. Les tentatives d'améliorer la perfusion cérébrale dans les zones cérébrales ischémiées, par hyper-et hypocapnie, se sont révelées inefficaces. Le présent rapport décrit notre expérience d'utilisation de routine d'un shunt intracarotidien au cours des 17 dernières années. Ce type de shunt offre plusieurs avantages: il maintient un débit sanguin cérébral inchangé malgré le clampage; le monitoring cérébral devient inutile; l'opération peut être faite sans précipitation. Si le tube est bien mis en place, il ne lèse pas la paroi artérielle et ne doit pas détacher d'embols. La présence du tube dans la lumière artérielle ne gène pas la mise en évidence des lésions d'athéromatose; elle facilite la suture artérielle et évite les erreurs de technique qui pourraient être responsables de sténoses. Nous avons comparé les résultats de la chirurgie carotidienne dans des séries de malades opérés avec et sans shunt interne. Une revue de la littérature confirme notre impression: le shunt ramène à la normale l'EEG et le débit sanguin cérébral. Le shunt est également utile pour la chirurgie des anévrismes de la carotide interne, des coudures de ce vaisseau, des tumeurs du sinus carotidien et des bypass carotido-sous-claviers.
    Notes: Abstract Safety of carotid artery surgery depends on proper case selection, meticulous surgical technique, and appropriate protection of the brain during carotid artery cross-clamping. Various methods have been devised to determine the adequacy of collateral circulation, none of which has been proven practical and totally reliable. Attempts at increasing cerebral perfusion to the ischemic portion of the brain by induced hypertension, hypercarbia, and hypocarbia have been ineffective. The purpose of this presentation is to report our experience with routine intraluminal shunting in carotid artery surgery during the past 17 years. Advantages of routine shunting include maintenance of regional cerebral blood flow at the preclamping level and the elimination of any need for monitoring and haste during surgery. Insertion of the tube, properly done, does not injure the arterial wall and should not cause embolization. The presence of the tube within the arterial lumen does not interfere with exposure of the atheroma, yet it facilitates repair of the incision and prevents stricture by faulty suturing technique. Results of carotid artery surgery measured by the incidence of stroke are compared between shunted and nonshunted series. A review of the literature confirms our impression that shunting reverses ischemic changes detected by EEG and regional cerebral blood flow determinations. The usefulness of shunting in the surgical management of internal carotid aneurysm, kinked carotid artery, carotid body tumor, and carotid-subclavian bypass graft is also described.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1432-2161
    Keywords: Fatty tumors ; Lipoma ; Liposarcoma ; Computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of computed tomography (CT) in the evaluation of fatty tumors of the somatic soft tissues was investigated. Six surgically proven cases of fatty tumors were studied preoperatively by CT and standard radiographic means — conventional radiographs, xeroradiography, and angiography. Our case material included a simple lipoma, two infiltrative lipomas, an angiolipoma, and two liposarcomas. The radiologic-pathologic correlation was evaluated with respect to the various imaging modalities. The unique tissue characteristics of fatty tumors makes them particularly adaptable to CT scanning. In addition to its ability to define accurately tissue densities, the facility of CT in depicting depth, size, and extent of the lesion in the axial plane was found to be most useful in the preoperative evaluation of our case metarial.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1432-2242
    Keywords: Disease ; Susceptibility ; Polymorphism ; Resistance ; E.coli
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Evidence is presented that a dominant allele, S, is expressed as a receptor for K88 on the brushborder surface of the pig intestinal cell. The homozygous recessive (ss) lacks this receptor. The receptor enables K88 — positive coliforms to adhere to the gut of the piglet which they must do if they are to cause neonatal diarrhoea. The homozygous recessive is thus a disease resistant animal. A possible reason for the persistence of the dominant (susceptible) gene is given.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 9
    ISSN: 1432-0509
    Keywords: Colon, duplication ; urinary tract, anomalies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case is presented in which complete colonic duplication is associated with genitourinary and bone abnormalities including a complete duplication of the urethra. The etiology, appearance, clinical course, and classification of various large bowel duplications are discussed.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1432-0509
    Keywords: Abdomen, hernia ; Spigelian hernia, diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case is reported in which the preoperative diagnosis of a Spigelian hernia containing both large and small bowel was made by radiographic means. The anatomy, clinical findings, and radiologic picture of this condition are discussed.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...