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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 31 (1978), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Operations on the sound conduction apparatus require that the Eustachian tube is functioning normally. Since the clinical function tests such as Valsalva and Toynbee do not provide satisfactory results in every case, the radiographical examination of the tube becomes very significant. The routine radiograms of the tube made since 1966, employing our own trans-tympanic technique enabled us to obtain completely accurate filling pictures under physiological conditions. During the past 2 years we have increased our knowledge of tubal status by means of cinematographic studies. This technique facilitates an optimal functional and structural evaluation of the eustachian tube during flow of the contrast medium through the entire length. In this way, any pathological condition such as stricture or edema of the mucosa can be demonstrated. This simple method, apart from its diagnostic significance in evaluating the tube, also offers a simultaneous therapeutic effect through the use of contrast medium containing iodine.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Contribution to Portmann's approach, I like to mention our own modifications in the form of saccotomy and decompression of the posterior semi-circular canal, until perilymph leakage is noticed from the porus bone as the skin perscipitates during the warm season. Postauricular incision; mastoidectomy. The endolymphatic sac will be exposed, which is a durai duplication of the small brain at the posterior wall, lying between sigmoid sinus and inferior to the posterior semicircular canal. The lateral wall of the sac is incised and removed. In addition to this, the posterior semicircular canal is thinned with the diamond drill, until the perilymph fluid leaks out slowly. These remain uncovered. One must take care not to suck this fluid. In this way we achieve both — a direct and indirect decompression of endolymphatic system. Results of the postoperative check up 3 years in 30 cases after this method is demonstrated.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Demonstration of the operative technique of eardrum-perforations. After cutting the edge of the perforation and curettage of the drum inner layer, the tympanic cavity is filled with reverin-soaked gelfoam, leaving the tubo-fenesteral lane free. The thin pieces of prepared homo-septal cartilages with temporal fascia are implanted unterneath the eardrum remnant so that it broadly unterlaps the eardrum defects. Finally, the transplant is covered with an adaptic sheet and the ear canal is plugged with a reverin-soaked gelfoam for 4–5 weeks, until the transplants have taken and wound healed. This modified method has the advantage that the recidive perforations or the formation of adhesions with the tympanic cavity can almost certainly be prevented. We have found that this procedure is especially suitable for perforations of the central eardrums as well as for marginal defects. In the 98 cases that we have operated upon to date, the functional hearing results are found to be optimal.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-4726
    Keywords: Intracellular potentials ; Ultrastructure ; Hair cells ; Labyrinth receptors ; Reptilia (Crocodilia, Gekkonidae)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Different biopotentials, following a mechanical stimulus, were recorded from single hair cells of the reptilian labyrinth, with electronoptically circumscript localizations: 1. From the apical cell pole, the receptor potential, intracellular or from the ciliary surface, within the physiological range proportional to stimulus amplitude, frequency or phase, without delay, and with no real threshold of mechanosensitivity, as measured by ciliary displacement amplitude or velocity. 2. From the synaptic zone, in the basal region of the hair cell, or from contacting nerve endings, the synaptic potentials, local excitatory or inhibitory processes, respectively, with measurable latencies and with non-linear distortion. 3. From the (dendritic) endings of the first afferent neuron (or neurons), spike-shaped action potentials, synchronized by the (excitatory) synaptic potentials. Characteristic curves were plotted as a quantitative representation of the mechano-electric input-output relations of the different types of hair cells. For proceeding morphological and physiological system analysis, the comparison of the different submammalian inner-ear receptor systems gives us some new possibilities of a closer correlation between ultrastructure and function.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This film demonstrates the technique of replacement of the entire ossicular chain with an L-shaped homo-incus in cases where this is missing due to chronic otitis media (cholesteatoma). In each case the radical mastoid cavity is converted into an extended simple mastoid by reconstruction the posterior meatal bony wall with allo, cartilage (preserved septal or rips) preventing the formation of niches. The grafting method differed according to spatial condition of the bridge as well as the condition of the tegmen aditus. This is a modification of previous attempts. Good hearing result of one case is shown.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Invertase formation in the yeast Saccharomyces cerevisiae is subject to repression by hexoses in the growth medium. Mutagen-induced (ethyl methanesulfonate or N-methyl-N'-nitro-nitrosoguanidine) invertase hyperproducer mutants have been derived from the SUC3 MAL3 strain EK-6B by selecting for their ability to grow on media containing the sugar raffinose plus 2-deoxy-D-glucose (2DG). Raffinose like sucrose is a β-fructoside which can be hydrolyzed by yeast invertase (β-fructofuranoside fructohydrolase). These mutants, designated dgr, produce higher levels of invertase (α-glucosidase levels are also elevated but to a lesser extent) under conditions normally repressing invertase biosynthesis in the parent. Invertases of mutants dgr2 and dgr3 are indistinguishable from that of EK-6B with respect to their Km's for sucrose and thermal labilities. Genetic studies revealed that dgr2 and dgr3 are recessive and unlinked to the SUC3 gene.
    Type of Medium: Electronic Resource
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