Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-2307
    Keywords: Angioblastic Meningioma ; Hemangioblastoma ; Hemangiopericytoma ; Specific Red Cell Adherence ; Endothelial Cell ; Interstitial cell ; Pericyte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The presence of blood group isoantigens in vascular endothelium cells was used in order to identify cells of endothelial origin in CNS tumors. 70 cerebrospinal tumors coded as “angioblastic meningiomas” and 30 cerebellar hemangioblastomas were examined for the detection of BG isoantigens by the specific red cell adherence (SRCA) test by Davidson (1972). In cerebellar and supratentorial hemangioblastomas a positive SRCA reaction in endothelial cells forming the prominent component of this neoplasm was opposed by a negative reaction in the large majority of interstitial (stroma) cells that argues against their endothelial origin. Identical behavior of SCRA test supports the histogenetic identity of hemangioblastomas and angioblastic meningiomas. A consistently negative SRCA reaction in cerebrospinal hemangiopericytomas except for the endothelial cells lining the capillaries supports the concept of a non-endothelial (pericytic) histogenesis of this neoplasm. Richly vascularized meningiomas with positive SRCA reaction restricted to vascular endothelial cells can be separated from angioblastic meningiomas, although transition forms are likely to occur. Angioblastic meningiomas suggested to originate from vasoformative elements (endothelium and pericytes) were found to represent 3.2 percent of a biopsy sample of 660 cases with cerebrospinal meningiomas. Their relationship to primary meningeal neoplasms needs further elucidation.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1591-9528
    Keywords: 3-Acetylpyridin ; Antimetabolits ; Bromthalein ; NAD ; NADP ; 3-Acetylpyridin ; Antimetaboliten ; Bromthalein ; Nicotinsäureamidadenindinucleotid (NAD) ; Nicotinsäureamidadenindinucleotidphosphat (NADP)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 3-Acetylpyridin, intraperitoneal injiziert, bewirkt eine Verminderung der Ausscheidung von Bromthalein in die Galle durch Hemmung der Sekretion dieser Substanz. Biochemische Untersuchungen haben in der Rattenleber dabei einen Abfall des Lactatgehaltes und der Adenosintriphosphatkonzentration sowie eine Abnahme der Enzymaktivitäten der Glucose-6-phosphatdehydrogenase und der 6-Phosphogluconatdehydrogenase aufgedeckt. Sowohl für diese Stoffwechselveränderungen als auch für die Sekretion von Bromthalein bestanden Dosisbeziehungen. Es wird diskutiert, ob zwischen den gefundenen Stoffwechselveränderungen und der Bromthalein-Sekretion ursächliche Zusammenhänge bestehen.
    Notes: Summary 3-Acetylpyridin was found to inhibit the secretion of bromthalein. The associated decrease of lactate and adenosintriphosphate content of the rat liver and the lower activity of the glucose-6-phosphatdehydrogenase and 6-phosphogluconatedehydrogenase are discussed and found to be related to bile- and bromthalein secretion.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1591-9528
    Keywords: Adrenal cortex activity ; Dehydration ; Saluretics ; Nebennierenrindenaktivität ; Entwässerung ; Saluretika
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 1. Es wurde die Nebennierenrindenaktivität der Ratte nach Entwässerung mit Saluretika und im Durstzustand (8 Tage Trinkwasserentzug) geprüft. Zur Entwässerung wurde den Tieren 1, 2 und 3 Tage lang dreimal täglich Furosemid (40 mg/kg) oder Hydrochlorothiazid (1,25 mg/kg) per os verabreicht. 2. Nach Furosemidapplikation waren als Zeichen einer Aktivitätssteigerung der Nebennieren der Plasmacorticosteronspiegel und das Nebennierengewicht signifikant erhöht gegenüber den Kontrolltieren, der Cholesteringehalt der Nebennieren niedriger. Im Durstzustand und nach Entwässerung mit Hydrochlorothiazid lagen jedoch die Plasmacorticosteronwerte und der Cholesteringehalt der Nebennieren im Bereich der Streuung der Normalwerte. Das Nebennierengewicht dieser Tiere war höher als normal, aber signifikant geringer als nach Furosemidentwässerung. 3. Aus den vorliegenden Befunden kann geschlossen werden, daß der bekannte ödeminhibierende Effekt des Furosemids auf eine Stimulierung des Hypophysen-Nebennierenrinden-Systems zurückzuführen ist. Dafür spricht auch das Fehlen der ödemhemmenden Eigenschaften des Furosemids nach Entfernung der Nebennieren.
    Notes: Summary 1. Experiments were performed to prove the activity of the adrenal cortex of rats either dehydration by saluretics or prolonged water deprivation (8 days). For dehydration by saluretics furosemide (40 mg/kg) or hydrochlorothiazide (1,25 mg/kg) were given three times daily through 1, 2 and 3 days. 2. After the administration of furosemide both plasmacorticosterone and the weight of the adrenals were significantly increased, cholesterol contents of the adrenals decreased. The thirsting rats and the animals dehydrated by hydrochlorothiazide showed normal values of plasmacorticosterone and adrenal cholesterol, adrenal weight wag higher than normal, but lower than after dehydration by furosemide. 3. The above mentioned results lead to the conclusion, that the well-known inhibition of edema by furosemide is caused by the stimulation of the pituitary-adrenal-system. This is indicated also by the absence of edema-inhibition after furosemide administration in adrenalectomized rats.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] FIG. 1 Moderately differentiated gastric adenocarcmoma. a, Positive MCAR (BG-B); 6, negative MCAR (BG-A). Serial sections. X285, Haemotoxylin and eosin (HE). The specimens were fixed in neutral buffered formalin, embedded in paraffin and subsequently treated for the demonstration of blood group ...
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In three patients with chronic hepatic porphyria (porphyria cutanea tarda) kidney biopsy specimens were investigated histologically by fluorescence microscopy. Typical red fluorescence indicating porphyrin deposits was found in the epithelial cells of convoluted renal tubuli and the loops of Henle. In contrast to these findings the uriniferous tubuli and the malpighian glomeruli did not show any porphyrin fluorescence. It is open to discussion, whether the porphyrin deposits are due to active resorption and secretion or the phenomenon of passive imbition of distinct parts of the renal tubular system is observed.
    Notes: Zusammenfassung Bei 3 Patienten mit chronischer hepatischer Porphyrie wurden erstmals Nierenbiopsiecylinder histologisch mittels Fluorescenzmikroskopie auf das Vorkommen von Porphyrinen untersucht. Porphyrinablagerungen wurden in den Epithelien der Hauptstücke und der angrenzenden Henleschen Schleifen gefunden, während Sammelrohre und Glomerula frei von Porphyrinen waren. Es wird diskutiert, ob aktive Sekretion oder Resorptionsphänomene die Porphyrinablagerungen in bestimmten Tubulusabschnitten bedingen, oder ob lediglich eine passive Imbibition des Gewebes (mit Porphyrinen) vorliegt.
    Type of Medium: Electronic Resource
    Signatur Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...