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  • 1965-1969  (41)
  • 1945-1949  (7)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 5 (1965), S. 26-39 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Krankengeschichten von zwei Brüdern, die wahrscheinlich an “Dégénérescence systématisée optico-cochléo-dentelée” (Nyssen-van Bogaert) litten, wurden mitgeteilt und die am Probanden, dem älteren Bruder, erhobenen Sektionsbefunde beschrieben. Zusammen mit den beiden neuen Beobachtungen sind nunmehr neun Fälle dieser Krankheit bekannt, die sowohl klinisch als auch pathologisch-anatomisch miteinander verglichen werden. Als gemeinsamer Befund liegt den fünf autoptisch gesicherten Beobachtungen eine Degeneration der Opticus-, Cochlearis-, Dentatum-und medialen Schleifensysteme zugrunde. Dagegen bleiben die basalen Ganglien und das Zwischenhirn vom Prozeß weitgehend verschont. Eine erhebliche Nervenzellichtung der Großhirnrinde scheint vor allem bei den im Säuglingsalter beginnenden Fällen vorzukommen. Die in unserem Fall auffallend schwere Kleinhirnrindenschädigung war auf Grund ihres Verteilungsmusters als Krampfschaden zu deuten.
    Notes: Summary Clinical observations of two brothers and pathoanatomical alterations on the older brother were found to be very similar to those in cases reported in the literature as “dégénérescence systématisée optico-cochléo-dentelée”. Including these two observations, a total of 9 patients believed to have been affected by this condition are now known. Clinical and pathological features are critically compared and their implications discussed. While some definite differences, possibly determined by the age of onset of the disease, exist, the common denominator is seen in a selective, systematized degeneration of the optic, the cochlear, the dentate and the medial lemniscal systems, a process which correlates well with the evolution of the clinical picture. The basal ganglia and most of the diencephalon remain unaffected. Degeneration of the pallium was noted in some instances, the degree of which relates well with the motorsensory retrogression. Cerebellocortical damage was severe only in our observation and is considered to be ictogenic.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1365-2621
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    ISSN: 1433-9285
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Résumé On résume les résultats expérimentaux concernant la chaleur spécifique à basse température des métaux de transition et de leurs alliages. Particulièrement, les variations de la contribution électronique sont discutées sur la base d'un recueil complet des mesures.
    Abstract: Zusammenfassung Die experimentellen Ergebnisse zur spezifischen Wärme der Übergangsmetalle und ihrer Legierungen bei tiefen Temperaturen sind übersichtlich dargestellt. Die Diskussion betrifft vor allem die Variationen des elektronischen Anteils und stützt sich auf eine vollständige Zusammenstellung der Meßresultate.
    Notes: Abstract The article reviews experimental results on the low temperature specific heat of the transition metals and their alloys. Particularly discussed are the variations of the electronic part on the basis of a complete compilation of measurements given.
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  • 5
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé L'action adrénocorticotrope d'un polypeptide à 25 acides aminés, comprenant 3 modifications de structure par rapport à la séquence 1–25 de l'ACTH naturelle est étudiée et démontrée. La destruction enzymatique de ce pentacosapeptide paraît être plus lente dans le sang que dans les tissus musculaire et sous-cutané. L'augmentation de la dose injectée produit un allongement de la durée de stimulation de la cortico-surrénale.
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  • 6
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary One of the authors has previously reported on a method which consists in the utilization of an artifical radioactive isotope (Zn63), suspended in a suitably prepared solution ofpectin, for the production oflocalized biological radiation effects. This « macromolecular occlusion » of the radioactive isotope enables one to perform intraperitoneal injections (in cases of cancer of the ovaries with severe metastatic peritoneal extension), evidently also instillations in cavernous organs, and furthermore direct intratumoral injections, without diffusion of the radioactivity outside the treated areas, as shown both by autoradiographs and controls of blood and urine specimens with a Geiger counter. The authors investigated further whether this procedure would also be suitable for obtaining, by means ofintravenous injections, alocalized radiation effect within thelungs, as presumably the radiozinc, held in the large molecules of pectin, could thus be retained in the pulmonary capillaries. Intravenous injections of such a pectin solution containing radiozinc were performed on rabbits, and autoradiographic controls gave evidence of this expected fixation within the lungs. For the purpose of preliminary clinical investigation 40 millicuries of Zn63 suspended in 6 cm3 of a 3 p. c. isotonic pectin solution were injectedintravenously in a female patient with mainly pulmonary metastases of a previously operated hypernephroma. This patient had been also submitted to X-ray therapy. In spite of a poor general condition, the injection was well tolerated. Autoradiographic controls showed quite clearly that the radioactivity remains precisely localized within the pulmonary areas. No radioactivity whatsoever was demonstrated with the counter in the urine eliminated by this patient after the injection, a fact which points to a rather amazing accuracy of the fixation of the radiozinc in the lungs. This first clinical experience seems quite interesting in view of improving the therapeutic possibilities of pathological, especially neoplastic pulmonary conditions.
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 210 (1966), S. 847-848 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In attempts to determine the ultrastructural organization of the RNA-protein complex, by means of RNase digestion techniques, Ruthmann was unable to determine conclusively whether the RNA was directly bound to fibrillar protein or was carried on ribosomes presumed present in the complex. We have ...
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 20 (1948), S. 993-993 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 10
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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