Wiley InterScience Backfile Collection 1832-2000
Chemistry and Pharmacology
Twelve new spiro acetal metabolites, the palmarumycins C1-C8, (1-8), C11 (11), C12 (12), C15 (15), C16 (16), and three known representatives (10, 13, 14) of this new class of antibiotics were isolated from Coniothyrium sp. The compounds show antibacterial, antifungal and herbicidal activity at concentrations of 10-6-10-4 mol/l. The structures of palmarumycin C2 (2), palmarumycin C3 (3), and palmarumycin C5 (5) were confirmed by X-ray structure analysis.
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