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  • 1
    Call number: ZZ1978:3a ; ZZ1978:3b/Mag ; ZZ1978:3/Mag
    Keywords: Deutsches Krebsforschungszentrum Heidelberg ; Academies and Institutes ; Neoplasms ; DKFZ-publications ; Germany
    Notes: Nachdruck aus der Festschrift zur Einweihung der Betriebsendstufe am 25. September 1972.
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    ZZ1978:3a available
    ZZ1978:3b/Mag departmental collection or stack – please contact the library
    ZZ1978:3/Mag departmental collection or stack – please contact the library
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  • 2
    Call number: YY Diss Baue/Mag
    Keywords: DKFZ-publications / academic dissertations
    Pages: 83 p. : 73 Abb.
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    YY Diss Baue/Mag departmental collection or stack – please contact the library
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  • 3
    Call number: QZ202:120b ; QZ202:120a/Mag ; QZ202:120/Mag
    Keywords: Neoplasms / etiology ; Mutation
    Notes: 1. Ex. Kopie der Originalausgabe, 2. u. 3. Ex. Reprint von 1988.
    Pages: 72 p. : ill.
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    QZ202:120b available
    QZ202:120a/Mag departmental collection or stack – please contact the library
    QZ202:120/Mag departmental collection or stack – please contact the library
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  • 4
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1017
    Keywords: Fluorescence polarization degree ; Fusion ; Label migration ; Lipid migration ; Cell membrane ; Virus envelope
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The fluorescence depolarization of 1,6-diphenyl-hexatriene was used to study the dynamic properties of the hydrophobic regions of the lipid envelopes of ortho- and paramyxoviruses as well as of the Rous sarcoma virus and of the membrane lipids of susceptible and nonsusceptible cells. The systems investigated where active and inactive influenza viruses, and NDV virus acting on chick embryo fibroblasts and Rous sarcoma virus acting on susceptible (C/E) and nonsusceptible (C/B) chicken-cell. Polarization degrees and mean rotational correlation times of DPH embedded in viral lipids were significantly higher than those of DPH in the cell membranes, due to a higher rigidity of the virus envelopes. When suspensions of labelled viruses and unlabelled cells or unlabelled viruses and labelled cells were mixed, a characteristic change of the fluorescence polarization degrees with time was observed. This behaviour was ascribed to a label transfer from virus to cell membranes or vice versa. While the rate constants of label transfer from virus to cells and cells to virus were about the same for the penetrating viruses the rate constants of label release from inactive virus to cells were much larger than for the migration in the opposite direction.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 47 (1929), S. 766-766 
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1017
    Keywords: Circular dichroism ; Exciton interaction ; Purple membrane ; Membrane reconstitution ; Binding model
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract We recently presented evidence showing that the visible CD spectrum of the purple membrane from Halobacterium halobium consists of two contributions: a broad positive band centered at the absorption maximum due to the interaction of the chromophore with the protein to which it is bound, and an exciton coupling band due to the interaction between chromophores of adjacent bacteriorhodopsin molecules in the hexagonal surface lattice (Heyn et al., 1975). This interpretation receives strong support from the present experiments in which the chromophore-free membrane is reconstituted by the addition of retinal. Since the coupling signal arises from the interaction between pairs of neighboring chromophores, its contribution to the spectrum would be expected to be very small in the initial stages of the titration experiment, but increasing quadratically with the percentage reconstitution. The broad positive band, on the other hand, is expected to increase linearly with the percentage reconstitution. On the basis of these considerations a satisfactory explanation of the CD reconstitution experiments could be given. Since it appears to be impossible to explain the titration experiments without the quadratic term, we conclude that chromophore-chromophore interactions play an important role. No significant changes in secondary structure upon reconstitution could be detected consistent with our binding model which neglects cooperativity.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1017
    Keywords: Electric field ; Magnetic field ; Suspended particle ; Magnetic sensitivity ; Organism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract We observed that particles, suspended in an electrolyte and brought into crossed magnetic and electric fields of low intensities, will deviate in the central part of the electrophoresis chamber of a standard Zeiss Cytopherometer with a component vertical to both fields. The direction and magnitude, however, were sharply at variance with what would be expected by the action of the Lorentz force (EMF) on the surface of the particles. The magnitude of the deviation depends upon the magnetic and electric field strength, the ion concentration of the suspension medium and the geometry of the chamber. The movement of the particles is due to streaming of the electrolyte which is mainly caused by inhomogeneities of the electric field in the electrophoresis chamber. The magnitude of the effect is high enough to occur under physiological conditions. Magneto-electrophoretic streaming might eventually act as a transducer mechanism which could explain the ability of some animals to orientate themselves in the geomagnetic field.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Dans une premiere étape, on a procédé chez 4 chiens à la construction d'une poche de Heidenhain (PH) et chez 3 autres à une poche de Pavlov (PP). Chez 2 des chiens porteurs d'une poche de Pavlov on a aussi installé une canule oesophagienne. Chez tous les chiens, dans une 2ème et 3ème étape on a procédé respectivement à une vaguotomie proximale sélective (VPS) et à une pyloroplastie sous-muqueuse (P). Chez les chiens porteurs d'une PP et d'une canule oesophagienne, on a procédé à un test de repas simulé avant et après la VPS. Chez tous les autres animaux on a procédé à l'épreuve du repas après la completion des 3 étapes chirurgicales. Le repas simulé a produit une augmentation significative des taux de gastrine après la VPS mais la sécrétion d'acide a été abolie dans la PP. Après repas, les taux de gastrine se sont élevés significativement chez tous les chiens. Dans la PH, la sécrétion d'acide a été proportionnelle aux taux de gastrine, tandis dans la PP, après VPS, la sécrétion d'acide a été inhibée, malgré l'élévation post-brandiale des taux de gastrine. La construction d'une pyloroplastie a subséquemment réduit de faÇon significative la mise en circulation de gastrine chez tous les chiens. Cepandant, la sécrétion d'acide a diminué significativement seulement chez les chiens porteurs de PH.
    Notes: Abstract In a first operative stage, 4 dogs were prepared with Heidenhain pouches (HP) and 3 with Pavlov pouches (PP), 2 of the latter with an additional esophageal cannula. In a second stage all dogs had a selective proximal vagotomy (SPV), and in a third stage a submucosal pyloroplasty (P). Sham feeding experiments were carried out on the 2 dogs with PP and an esophageal fistula before and after SPV. Feeding tests were performed in all animals after the three operative procedures. Gastrin release after sham feeding increased significantly after SPV, whereas PP acid secretion was abolished. Gastrin release after feeding increased significantly after SPV in both HP and PP dogs. Acid secretion from HP was correlated with the changes in postprandial serum gastrin levels. PP acid secretion was diminished after SPV, in spite of the elevated gastrin levels. Subsequent pyloroplasty induced a significant decrease in the postprandial gastrin levels in both HP and PP dogs. However, acid secretion decreased significantly only in HP dogs.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 273 (1929), S. 780-793 
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Die ursächlichen Bedingungen für den An- und Abau der Zahnhartsubstanzen liegen nicht in Wesensverschiedenheiten dieser Gewebe selbst, vielmehr ganz allein in den Zuständen und Veränderungen der angrenzenden Weichgewebe und in ihren Blutstromverhältnissen. Die Zahnsubstanzen verhalten sich gleich dem Knochengewebe sowohl beim An- als auch beim Abbau vollkommen passiv. Chemische Verschiedenheiten oder Verschiedenheiten des mechanischen Widerstandes der Zahn- und Knochengewebe, wie sie im Verkalkt- oder Unverkalktsein gegeben erscheinen, können nicht als Anregungen zu Resorptionsvorgängen betrachtet werden, sondern lediglich, worauf schonPommer wiederholt hinwies, für die Form der Ostoklasten und Lacunen sowie für die Tiefe der letzteren von Belang und Einfluß sein.
    Type of Medium: Electronic Resource
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