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  • 1
    Publication Date: 2016-01-30
    Description: The smooth disappearance of antiferromagnetic order in strongly correlated metals commonly furnishes the development of unconventional superconductivity. The canonical heavy-electron compound YbRh2Si2 seems to represent an apparent exception from this quantum critical paradigm in that it is not a superconductor at temperature T 〉/= 10 millikelvin (mK). Here we report magnetic and calorimetric measurements on YbRh2Si2, down to temperatures as low as T approximately 1 mK. The data reveal the development of nuclear antiferromagnetic order slightly above 2 mK and of heavy-electron superconductivity almost concomitantly with this order. Our results demonstrate that superconductivity in the vicinity of quantum criticality is a general phenomenon.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schuberth, Erwin -- Tippmann, Marc -- Steinke, Lucia -- Lausberg, Stefan -- Steppke, Alexander -- Brando, Manuel -- Krellner, Cornelius -- Geibel, Christoph -- Yu, Rong -- Si, Qimiao -- Steglich, Frank -- New York, N.Y. -- Science. 2016 Jan 29;351(6272):485-8. doi: 10.1126/science.aaa9733. Epub 2016 Jan 28.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Walther Meissner Institut fur Tieftemperaturforschung der Bayerischen Akademie der Wissenschaften, 85748 Garching, Germany. Max Planck Institute for Chemical Physics of Solids, 01187 Dresden, Germany. steglich@cpfs.mpg.de eschuber@ph.tum.de qmsi@rice.edu. ; Walther Meissner Institut fur Tieftemperaturforschung der Bayerischen Akademie der Wissenschaften, 85748 Garching, Germany. Physikdepartment, Technische Universitat Munchen, 80333 Munchen, Germany. ; Walther Meissner Institut fur Tieftemperaturforschung der Bayerischen Akademie der Wissenschaften, 85748 Garching, Germany. Max Planck Institute for Chemical Physics of Solids, 01187 Dresden, Germany. ; Max Planck Institute for Chemical Physics of Solids, 01187 Dresden, Germany. ; Max Planck Institute for Chemical Physics of Solids, 01187 Dresden, Germany. Physics Institute, University of Frankfurt, 60438 Frankfurt, Germany. ; Department of Physics, Renmin University of China, Beijing 100872, China. Department of Physics and Astronomy, Collaborative Innovation Center of Advanced Microstructures, Shanghai Jiaotong University, Shanghai 200240, China. ; Department of Physics and Astronomy, Rice University, Houston, TX 77005, USA. steglich@cpfs.mpg.de eschuber@ph.tum.de qmsi@rice.edu. ; Max Planck Institute for Chemical Physics of Solids, 01187 Dresden, Germany. Center for Correlated Matter, Zhejiang University, Hangzhou, Zhejiang 310058, China. Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China. steglich@cpfs.mpg.de eschuber@ph.tum.de qmsi@rice.edu.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26823424" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2018-11-01
    Description: A methionine substitution at lysine-27 on histone H3 variants (H3K27M) characterizes ~80% of diffuse intrinsic pontine gliomas (DIPG) and inhibits polycomb repressive complex 2 (PRC2) in a dominant-negative fashion. Yet, the mechanisms for this inhibition and abnormal epigenomic landscape have not been resolved. Using quantitative proteomics, we discovered that robust PRC2 inhibition requires levels of H3K27M greatly exceeding those of PRC2, seen in DIPG. While PRC2 inhibition requires interaction with H3K27M, we found that this interaction on chromatin is transient, with PRC2 largely being released from H3K27M. Unexpectedly, inhibition persisted even after PRC2 dissociated from H3K27M-containing chromatin, suggesting a lasting impact on PRC2. Furthermore, allosterically activated PRC2 is particularly sensitive to H3K27M, leading to the failure to spread H3K27me from PRC2 recruitment sites and consequently abrogating PRC2’s ability to establish H3K27me2-3 repressive chromatin domains. In turn, levels of polycomb antagonists such as H3K36me2 are elevated, suggesting a more global, downstream effect on the epigenome. Together, these findings reveal the conditions required for H3K27M-mediated PRC2 inhibition and reconcile seemingly paradoxical effects of H3K27M on PRC2 recruitment and activity.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
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  • 3
    Publication Date: 2014-04-12
    Description: The mammalian olfactory system has the natural capacity to regenerate throughout the animal's life span. Despite constant neurogenesis, olfactory sensory neurons project to precise, stereotypical positions in the brain. Here, we identify a critical period of olfactory sensory axon targeting during postnatal development in mouse. Perturbing axon projection beyond postnatal day 7 permanently disrupts targeting specificity of the sensory neurons. In addition, we find that the establishment of the convergence map requires perinatal sensory neurons. Late-born neurons appear to connect with prospective glomeruli based on homotypic interactions among neurons expressing the same odorant receptor. Our results reveal a developmental switch in axon guidance and a mechanism of circuit integration of adult-born neurons.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ma, Limei -- Wu, Yunming -- Qiu, Qiang -- Scheerer, Hayley -- Moran, Andrea -- Yu, C Ron -- New York, N.Y. -- Science. 2014 Apr 11;344(6180):194-7. doi: 10.1126/science.1248805.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24723610" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Axons/*physiology ; Doxorubicin/pharmacology ; Gene Expression Regulation, Developmental ; Mice ; Mice, Mutant Strains ; Nerve Regeneration/genetics/*physiology ; Olfactory Bulb/*growth & development/physiology ; Olfactory Receptor Neurons/*growth & development ; Potassium Channels, Inwardly Rectifying/genetics ; Receptors, Odorant/genetics/physiology ; Trans-Activators/antagonists & inhibitors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: In recent years, a series of non-linear optically active bis(benzylidene) ketones have been synthesized and investigated by electron crystallography. In most cases, structure refinement was possible by combining electron diffraction analysis and quantum-mechanical calculations with maximum-entropy methods. However, when the torsional angles between the phenyl rings and the C=C double bonds are strongly affected by the crystal field, this method fails because packing-energy calculations are not sufficiently sensitive. This problem can be solved by refining the approximate model with SHELXL, if the data set is sufficiently accurate and the model close to the correct structure. Here it is shown that a considerably superior data set can be obtained at 300 kV with on-line data acquisition.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 51 (1995), S. 1515-1517 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 2018-06-23
    Description: Spin Hall angle ( SH ) and spin diffusion length ( sd ) are the key parameters in describing the spin-charge conversion, which is an integral part of spintronics. Despite their importance and much effort devoted to quantifying them, significant inconsistencies in the reported values for the same given material exist. We report a self-consistent method to quantify both SH and sd of nonmagnetic materials by spin pumping with various ferromagnetic (FM) pumping sources. We characterize the spin-charge conversion for Pt and Pd with various FM combinations using (i) effective spin-mixing conductance, (ii) microwave photoresistance, and (iii) inverse spin Hall effect measurements and find that the pumped spin current suffers an interfacial spin loss (ISL), whose magnitude varies for different interfaces. By properly treating the ISL effect, we obtained consistent values of SH and sd for both Pt and Pd regardless of the ferromagnet used.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
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  • 7
    Publication Date: 2018-08-03
    Description: Strain engineering has emerged as a powerful tool to enhance the performance of known functional materials. Here we demonstrate a general and practical method to obtain super-tetragonality and giant polarization using interphase strain. We use this method to create an out-of-plane–to–in-plane lattice parameter ratio of 1.238 in epitaxial composite thin films of tetragonal lead titanate (PbTiO 3 ), compared to 1.065 in bulk. These thin films with super-tetragonal structure possess a giant remanent polarization, 236.3 microcoulombs per square centimeter, which is almost twice the value of known ferroelectrics. The super-tetragonal phase is stable up to 725°C, compared to the bulk transition temperature of 490°C. The interphase-strain approach could enhance the physical properties of other functional materials.
    Keywords: Materials Science, Physics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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