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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Experimental dermatology 8 (1999), S. 0 
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: A wide range of hypotheses such as focal infection, trophoneur- oses, and endocrine dysfunction, have been previously proposed to explain the pathogenesis of alopecia areata (AA). Currently, the most widely held belief is that AA is an autoimmune disease with cellular and/or humoral immunity directed against anagen hair follicle antigen(s). However, until recently evidence in support of an autoimmune mechanism of AA has been largely circumstantial. More fundamental evidence has recently been amassed in support of AA as an autoimmune disease by using animal models. These data include: 1) identification of cross-species hair follicle specific IgG autoantibodies, 2) The ability to induce AA in an animal model with transfer of skin from affected to naive individuals, and 3) the induction of disease by transfer of lymphocytes to human skin grafted to severe combined immunodeficiency mutant mice. A review of the pre- vious and current data related to the autoimmune basis of AA is provided to put into perspective the future studies needed to definitively determine whether AA is an autoimmune disease.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Sequence analysis of two independently isolated Eβk cDNA clones revealed that the Eβk molecule is identical to the Eβb molecule at the NH2-terminus. These data resolve a discrepancy between previously published amino acid and nucleotide sequences and indicate that the Eβ NH2-terminus is not as polymorphic as was once believed.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Smooth, c-axis oriented, superconducting thin films of YBa2Cu3O7−x and DyBa2Cu3O7−x have been grown on (100) MgO by organometallic molecular-beam epitaxy. To our knowledge this is the first report of this technique for the fabrication of this class of high Tc superconductors. Y (or Dy) β-diketonate organometallic sources are utilized with Ba and Cu metallic sources. Films are grown in situ by codepositing from these sources in an ozone ambient with a substrate temperature of 700 °C. The use of an active oxygen source (ozone) is required for decomposition of the organometallic sources as well as for the attainment of superconducting films in situ. The films are characterized by Tc's as high as 85 K and Jc's of 1.2×106 A/cm2 at 12 K and 2.4×103 A/cm2 at 77 K. In addition to the four point Tc and Jc results, alternating-current susceptibility measurements are also reported. The composition of the films has been determined by Rutherford backscattering spectroscopy, Auger and secondary ion mass spectroscopy analysis, with the smoothness of the films characterized by scanning tunneling microscopy.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The radioallergosorbent test (RAST) has been adapted to measure specific IgE antibodies in bloodstains. By incubating several allergen discs simultaneously with one stain extract, an allergy profile can be readily obtained from less than 50 μl of dried blood.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 30 (1987), S. 2054-2062 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Some studies of forced and unforced plane turbulent mixing layers have been conducted using two experimental and two computational approaches. The present paper contains an overall comparison and discussion of the measured and computed results. The experimental results include flow-visualization data using the smoke-laser technique and mean flow and turbulence measurements obtained with hot X wires and a two-component laser-Doppler velocimeter (LDV). The mean flow and turbulence results indicate that the two experimental techniques agree reasonably well for this shear flow. Two-dimensional computations of the measured mixing layers have also been conducted in a coordinated effort; one method uses the inviscid discrete vortex technique for a spatially developing layer and the other is based on an approximation to the Reynolds-averaged Navier–Stokes equations. The vortex method was found to give excellent results for the forced mixing layer while the Reynolds-averaged computations, with a modified turbulence model, were particularly successful at capturing the near-field viscous behavior that included the splitter plate wake.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 3251-3255 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The isothermal decay of the second-order nonlinear optical susceptibility of a guest-host azo dye methacrylate film was measured by second-harmonic generation at a series of temperatures. The decay curves were fit to Williams–Watt–Kohlrausch stretched exponentials. The activation energies and pre-exponential factors were found to agree with those derived from nonisothermal electric-field-induced second-harmonic generation measurements on similar films. It is concluded that a common underlying process involving a distribution of local relaxations governs the film behavior.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 63 (1993), S. 1005-1007 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Epitaxial barriers of ferromagnetic SrRuO3 have been used to fabricate high Tc superconductor-normal-superconductor Josephson junctions in the edge junction geometry. At small barrier thicknesses the SrRuO3 junctions follow the behavior of nonferromagnetic but otherwise closely related CaRuO3 junctions. A rapid disappearance of critical current is observed when the barrier thickness is increased to 250 A(ring). Possible origins of such a large critical thickness are discussed.
    Type of Medium: Electronic Resource
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