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  • American Institute of Physics (AIP)  (2)
  • Blackwell Science Ltd  (1)
  • 1
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The capability for making ongoing characterization measurements of the spatial resolution and spectral reflectance of the Wölter x-ray optics used at Nova is essential for the interpretation of data taken with these imaging diagnostics. Equally important is an assessment of the long-term performance of grazing incidence x-ray optics used in the harsh environment of an ICF target chamber. We have designed and are currently building an off-line facility for such a characterization. The facility will consist of an x-ray source with specially designed pinhole-target foil array, the Wölter optics housing, monitoring and measuring detectors, a data acquisition system, and an in situ alignment system for rapid periodical verification. Each component of this lab will be discussed, along with possible initial results. This work was performed under the auspices of the U. S. Department of Energy by the Lawrence Livermore National Laboratory under contract No. W-7405-ENG-48.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We have developed an off-line facility for very precise characterization of the reflectance and spatial resolution of the grazing incidence Wölter type I x-ray optics used at Nova. The primary component of the facility is a new, very versatile, high brightness x-ray source consisting of a focused DC electron beam incident onto a precision manipulated target-pinhole array. The data are recorded with a selection of detectors. For imaging measurements we use direct exposure x-ray film modules or an x-ray charge-coupled device camera. For energy-resolved reflectance measurements, we use lithium drifted silicon detectors and a proportional counter. An in situ laser alignment system allows precise location and rapid periodic alignment verification of the x-ray point source, the statically mounted Wölter optic, and the chosen detector. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Thirty-five patients with mycologically proven scalp infections were enrolled in a randomized, double-blind clinical trial with oral terbinafine (dose adjusted according to patient weight) for either 1 or 2 weeks. Patients were observed for 12 weeks; after 4 weeks, non-responders were offered an additional 4 weeks of treatment followed by a second observation period. The causative organisms were Microsporum canis (n = 12), Trichophyton tonsurans (n = 12) and other Trichophyton spp. (n = 11). The Trichophyton infections were treated effectively in five of nine (56%) patients treated for 1 week and 12 of 14 (86%) patients treated for 2 weeks. Three of the non-responders were treated for an additional 4 weeks, and one responded. In the Microsporum group only one of seven patients treated for 1 week and none of five treated for 2 weeks responded. However, treatment was effective in four of six (66%) patients treated for an additional 4 weeks. Mild to moderate adverse events believed to be drug related occurred in four patients in each of the two groups. Terbinafine is well tolerated, and requires 2 weeks of treatment in most patients with Trichophyton scalp infections and 4 weeks or more in Microsporum scalp infections, to achieve a successful clinical and mycological response.
    Type of Medium: Electronic Resource
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