Sensors, Vol. 18, Pages 1368: A Review on Bacteriorhodopsin-Based Bioelectronic Devices Sensors doi: 10.3390/s18051368 Authors: Yu-Tao Li Ye Tian He Tian Tao Tu Guang-Yang Gou Qian Wang Yan-Cong Qiao Yi Yang Tian-Ling Ren Bacteriorhodopsin protein extracted from Halobacterium salinarum is widely used in many biohybrid electronic devices and forms a research subject known as bioelectronics, which merges biology with electronic technique. The specific molecule structure and components of bR lead to its unique photocycle characteristic, which consists of several intermediates (bR, K, L, M, N, and O) and results in proton pump function. In this review, working principles and properties of bacteriorhodopsin are briefly introduced, as well as bR layer preparation method. After that, different bR-based devices divided into photochemical and photoelectric applications are shown. Finally, outlook and conclusions are drawn to inspire new design of high-performance bR-based biohybrid electronic devices.
Chemistry and Pharmacology
Electrical Engineering, Measurement and Control Technology