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  • 1
    Nature Publishing Group (NPG)
    Publication Date: 2018-06-19
    Description: Checkpoint inhibition: NK cells enter the scene Checkpoint inhibition: NK cells enter the scene, Published online: 18 June 2018; doi:10.1038/s41590-018-0142-y Tumor-associated natural killer cells have elevated expression of the checkpoint inhibitory receptor TIGIT. Monoclonal antibody–mediated blockade targeting TIGIT unleashes the anti-tumor activity of both natural killer cells and T cells in preclinical mouse models and efficiently delays tumor growth.
    Print ISSN: 1529-2908
    Electronic ISSN: 1529-2916
    Topics: Biology , Medicine
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