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  • Springer  (6,213)
  • American Chemical Society  (4,968)
  • Blackwell Science Pty
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  • 1
    Keywords: Toxicology ; Human Physiology ; Medicine ; Biochemistry ; Oncology ; Pharmacology/Toxicology ; Human Physiology ; Health Promotion and Disease Prevention ; Biochemistry, general ; Cancer Research ; Springer eBooks
    Description / Table of Contents: Preface -- Chapter I. Introduction -- 1.History of Discovery of Vitamin C -- 2.What is vitamin C? -- 3.Chemical Properties of Vitamin C as Anti-oxidant -- 4.Biological Activities as Co-factors -- 5.Scientific Background of Optimal Dose -- 6.How to take? -- 7.Adverse Effects -- Chapter II. Cardiovascular System -- Chapter III. Cancer -- Chapter IV. Immune system -- Chapter V. Respiratory System, Common Cold and Influenza -- Chapter VI. Central Nervous System -- Chapter VII. Aging -- Chapter VIII. Stress -- Chapter IX. Gastrointestinal (GI) System -- Chapter X. Liver -- Chapter XI. Skin -- Chapter XII. Eye -- Chapter XIII. Summary and Conclusion
    Abstract: This book presents the scientific evidence for the role of vitamin C in health and disease and offers new guidance on vitamin C intake in humans. The importance of vitamin C in preventing cancer and cardiovascular disease, its relevance to aging and stress, and its impacts on each of the human body systems are thoroughly assessed on the basis of the author’s extensive research and his deep understanding, as an anatomy professor, of the body as a whole. Findings published in the international scientific literature are fully taken into account, and due consideration is also given to empirical evidence, bearing in mind that mechanisms of action cannot always be precisely defined in the absence of human experiments. Beyond providing an up-to-date scientific perspective on the effects of vitamin C, the author hopes to promote human health worldwide by encouraging proper use of the vitamin. To this end, recommendations are made on the amount of vitamin C that should be taken daily and on the best way to take it. The book will be of interest to researchers, clinicians, and all others who wish to learn more about this vitamin and its significance
    Pages: IX, 184 p. 72 illus., 62 illus. in color. : online resource.
    Edition: 1st ed. 2019.
    ISBN: 9789402417135
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  • 2
    Keywords: Life sciences ; Cardiology ; Cytology ; Stem Cells ; Life sciences ; Stem Cells ; Cardiology ; Cell Biology ; Springer eBooks
    Pages: : digital.
    ISBN: 9781461440932
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  • 3
    Keywords: Medicine ; Gene Expression ; Biotechnology ; Genetic Engineering ; Bioinformatics ; Biological models ; Microbial genetics ; Biomedicine ; Gene Expression ; Systems Biology ; Biotechnology ; Microbial Genetics and Genomics ; Genetic Engineering ; Computational Biology/Bioinformatics ; Springer eBooks
    Pages: : digital.
    ISBN: 9789400745346
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  • 4
    Keywords: Medicine ; Human Genetics ; Biomedicine ; Human Genetics ; Molecular Medicine ; Biomedicine general ; Springer eBooks
    Description / Table of Contents: Part 1: Overview -- The Clinical Spectrum of Nuclear DNA-Related Mitochondrial Disorders -- Biochemical and Molecular Methods for the Study of Mitochondrial Disorders -- Part 2: Genes Involved in Mitochondrial DNA Biogenesis and Maintenance of Mitochondrial DNA Integrity -- Mitochondrial Disorders Associated with the Mitochondrial DNA Polymerase g: A Focus on Intersubunit Interactions -- Alpers-Huttenlocher Syndrome, Polymerase Gamma 1, and Mitochondrial Disease -- Deoxyguanosine Kinase -- 〈i〉MPV17〈/i〉-Associated Hepatocerebral Mitochondrial DNA Depletion Syndrome -- Mitochondrial DNA Multiple Deletion Syndromes, Autosomal Dominant and Recessive (POLG, POLG2, TWINKLE and ANT1) -- Defects in Mitochondrial Dynamics and Mitochondrial DNA Instability -- Depletion of mtDNA with MMA: 〈i〉SUCLA2〈/i〉 and 〈i〉SUCLG1〈/i〉 -- 〈i〉RRM2B〈/i〉-Related Mitochondrial Disease -- Part 3: Complex Subunits and Assembly Genes -- Complex Subunits and Assembly Genes: Complex I -- Mitochondrial Respiratory Chain Complex II -- Mitochondrial Complex III Deficiency of Nuclear Origin: Molecular Basis, Pathophysiological Mechanisms and Mouse Models -- Mitochondrial Cytochrome 〈i〉c〈/i〉 Oxidase Assembly in Health and Human Diseases -- Part 4: Mitochondrial Protein Translation Related Diseases -- Mitochondrial Aminoacyl-tRNA Synthetases -- Mitochondrial Protein Translation Related Disease: Mitochondrial Ribosomal Proteins and Translation Factors -- Disorders of Mitochondrial RNA Modification -- Part 5: Others -- Pyruvate Dehydrogenase Complex Deficiencies.-〈b〉 〈/b〉Nuclear Genes Causing Mitochondrial Cardiomyopathy -- Mitochondrial Diseases Caused by Mutations in Inner Membrane Chaperone Proteins -- Index
    Abstract: Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells.℗ In addition, the biogenesis, structure and function of mitochondria, including DNA replication, transcription, and translation, all require nuclear encoded genes.℗ Since mitochondria are present in every cell, every tissue, mitochondrial disorders usually affects multiple organs. 〈i〉Mitochondrial Disorders Caused by Nuclear Genes 〈/i〉discusses the〈i〉 〈/i〉biochemical, molecular, clinical, and genetic aspects〈i〉 〈/i〉of complex dual genome mitochondrial disorders. Chapters include genes involved in mitochondrial DNA biogenesis and maintenance of mitochondrial DNA integrity, complex subunits and assembly genes, and mitochondrial protein translation related diseases
    Pages: XII, 369 p. 32 illus., 20 illus. in color. : digital.
    ISBN: 9781461437222
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  • 5
    Call number: C060:228
    Keywords: Biometry ; Risk / Mathematical models ; Mathematical Statistics ; Statistics
    Description / Table of Contents: Risk assessment in lifetime data alalysis: Non-proportionality of hazards in the competing risks framework ; Semiparametric inference on the absolute risk reduction and the restricted mean survival difference ; Connecting threshold regression and accelerated failure time models ; Residuals and functional form in accelerated life regression ; Neyman, Markov processes and survival analysis ; Quantiles of residual survival -- Evaluation of predictions: Methods for evaluating prediction performance of biomarkers and tests ; Estimating improvements in prediction with matched case-control designs ; ROC analysis for multiple markers with tree-based classification ; Assessing discrimination of risk prediction rules in a clustered data setting ; Time-dependent AUC with right-censored data : a survey ; Subgroup specific incremental value of new markers for risk prediction -- Applications: Assessing the effects of imprinting and maternal genotypes on complex genetic traits ; Competing risks models and breast cancer : a brief review ; Quantifying relative potency in dose-response studies ; Development and validation of exposure biomarkers to dietary contaminants mycotoxins : a case for aflatoxin and impaired child growth ; Pharmaceutical risk assessment and predictive enrichment to maximize benefit and minimize risk : issues in product life cycle evaluation ; A multiple imputation approach for the evaluation of surrogate markers in the principal stratification causal inference framework ; Mapping return values of extreme wind speeds ; Decision analysis methods for selecting consumer services with attribute value uncertainty ; Evaluating incremental values form new predictors with net reclassification improvement in survival analysis
    Notes: "On October 12-14, 2011, the Biostatistics and Risk Assessment Center (BRAC) and the Department of Epidemiology and Biostatistics of the University of Maryland hosted an international conference entitled "Risk assessment and evaluation of predictions ... held in Silver Spring, Maryland ... This volume presents a broad spectrum of articles presented at the conference"--Page v.
    Pages: xi, 445 pages : illustrations (some color)
    ISBN: 9781461489801
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    C060:228 departmental collection or stack – please contact the library
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  • 6
    Keywords: Biochemistry ; Chemistry, Inorganic ; Cell Membranes ; Animal Biochemistry ; Inorganic Chemistry ; Membrane Biology ; Springer eBooks
    Description / Table of Contents: Membrane Transport Proteins and Receptors for Cadmium and Cadmium Complexes -- The Chemical Biology of Cadmium -- Interactions of Cadmium With Signaling Molecules -- Cell Organelles as Targets of Cadmium Toxicity -- Cadmium and its Impact on Genomic Stability
    Abstract: This book outlines the interaction of cadmium with the proteome and signalling molecules of mammalian cells. Chapters from expert contributors cover topics such as cadmium chemical biology, membrane receptors and transporters for cadmium and cadmium complexes, and targets of cadmium toxicity. Students and researchers working in bioinorganic chemistry will find this book an important account
    Pages: IX, 125 p. 13 illus., 9 illus. in color. : online resource.
    ISBN: 9783319896236
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  • 7
    Keywords: Medicine ; Vaccines ; Medical virology ; Wildlife management ; Biomedicine ; Virology ; Vaccine ; Fish & Wildlife Biology & Management ; Springer eBooks
    Pages: : digital.
    ISBN: 9783642298196
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  • 8
    Keywords: Otorhinolaryngology ; Neurosciences ; Otorhinolaryngology ; Neurosciences ; Springer eBooks
    Description / Table of Contents: Preface -- Visual Influence on Auditory Perception -- Cue Combination Within a Bayesian Framework -- Toward a Model of Auditory-Visual Speech Intelligibility -- An Object-Based Interpretation of Audiovisual Processing -- Hearing in a “Moving” Visual World: Coordinate Transformations Along the Auditory Pathway -- Multisensory Processing in the Auditory Cortex -- Audiovisual Integration in the Primate Prefrontal Cortex -- Using Multisensory Integration to Understand the Human Auditory Cortex -- Combining Voice and Face Content in the Primate Temporal Lobe -- Neural Network Dynamics and Audiovisual Integration -- Cross-Modal Learning in the Auditory System -- Multisensory Processing Differences in Individuals with Autism Spectrum Disorder
    Abstract: Auditory behavior, perception, and cognition are all shaped by information from other sensory systems. This volume examines this multi-sensory view of auditory function at levels of analysis ranging from the single neuron to neuroimaging in human clinical populations. Visual Influence on Auditory Perception Adrian K.C. Lee and Mark T. Wallace Cue Combination within a Bayesian Framework David Alais and David Burr Toward a Model of Auditory-Visual Speech Intelligibility Ken W. Grant and Joshua G. W. Bernstein An Object-based Interpretation of Audiovisual Processing Adrian K.C. Lee, Ross K. Maddox, and Jennifer K. Bizley Hearing in a “Moving” Visual World: Coordinate Transformations Along the Auditory Pathway Shawn M. Willett, Jennifer M. Groh, Ross K. Maddox Multisensory Processing in the Auditory Cortex Andrew J. King, Amy Hammond-Kenny, Fernando R. Nodal Audiovisual Integration in the Primate Prefrontal Cortex Bethany Plakke and Lizabeth M. Romanski Using Multisensory Integration to Understand Human Auditory Cortex Michael S. Beauchamp Combining Voice and Face Content in the Primate Temporal Lobe Catherine Perrodin and Christopher I. Petkov Neural Network Dynamics and Audiovisual Integration Julian Keil and Daniel Senkowski Cross-Modal Learning in the Auditory System Patrick Bruns and Brigitte Röder Multisensory Processing Differences in Individuals with Autism Spectrum Disorder Sarah H. Baum Miller, Mark T. Wallace Adrian K.C. Lee is Associate Professor in the Department of Speech & Hearing Sciences and the Institute for Learning and Brain Sciences at the University of Washington, Seattle Mark T. Wallace is the Louise B McGavock Endowed Chair and Professor in the Departments of Hearing and Speech Sciences, Psychiatry, Psychology and Director of the Vanderbilt Brain Institute at Vanderbilt University, Nashville Allison B. Coffin is Associate Professor in the Department of Integrative Physiology and Neuroscience at Washington State University, Vancouver, WA Arthur N. Popper is Professor Emeritus and research professor in the Department of Biology at the University of Maryland, College Park Richard R. Fay is Distinguished Research Professor of Psychology at Loyola University, Chicago
    Pages: XVI, 272 p. 70 illus., 49 illus. in color. : online resource.
    ISBN: 9783030104610
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  • 9
    Keywords: Medicine ; Dermatology ; Family medicine ; Internal Medicine ; Pediatrics ; Medicine & Public Health ; Dermatology ; Internal Medicine ; General Practice / Family Medicine ; Pediatrics ; Springer eBooks
    Edition: 2nd ed
    ISBN: 9783642280061
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  • 10
    Keywords: Medicine ; Emergency Medicine ; Radiology, Medical ; Cardiology ; Neurology ; Neurosurgery ; Medicine & Public Health ; Imaging / Radiology ; Neuroradiology ; Neurology ; Cardiology ; Emergency Medicine ; Neurosurgery ; Springer eBooks
    Pages: : digital
    ISBN: 9783642127519
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