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  • Ultrastructure  (3)
  • 1’-Ethylidenebis (L-tryptophan)  (1)
  • cultured cells
  • Springer  (4)
  • 1
    ISSN: 1432-0533
    Keywords: Primary rhabdomyosarcoma ; Brain tumor ; Ultrastructure ; Basal ganglia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Primary intracranial rhabdomyosarcoma is extremely rare. A case of primary rhabdomyosarcoma in the left basal ganglia is described in a 2-year-old boy. The investigations revealed no primary lesion elsewhere except in the brain. At the electron-microscopic level, the majority of the cells contained specific microfilamentous bundles, which were either distributed at random or organized in myofibrils identified by their cross striations with primitive Z band formation.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0533
    Keywords: Choroid plexus papilloma (CPP) ; Malignant DCPP ; Choroid plexus endothelium ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A disseminated choroid plexus papilloma (DCPP) with a malignant change in the cervico-spinal leptomeninges observed 4 years after the removal of choroid plexus papilloma (CPP), originating from the fourth ventricle, was studied under the electron microscope. Although the ultrastructure of intracranial CPP has been reported by several authors, there are just a few reports on DCPP. The present tumor was ultrastructurally very similar to normal choroid plexus, but the lack of the capillary fenestration and of invaginations of the epithelial basal plasmalemmas suggested that the epithelium was deprived of secretory function.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 62 (1984), S. 225-229 
    ISSN: 1432-0533
    Keywords: Dandy-Walker syndrome ; Dandy-Walker cyst ; Ependymal cell ; Ultrastructure ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ultrastructure of the wall of the Dandy-Walker cyst has been described rarely. A boy aged 2 years was confirmed clinically, neuroradiologically, and operatively as having a Dandy-Walker cyst in the posterior fossa. The cyst wall obtained during surgery consisted of an outer arachnoid cell layer, intermediate interwoven neuroglial strands, and an inner layer of cells which lacked the characteristic appearance of ependyma. An unusual finding was a small, buried island of ependymal cells in the intermediate layer of the neuroglial tissue. Ultrastructural study of the cyst wall provides a better understanding of the pathogenesis of the Dandy-Walker syndrome.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0738
    Keywords: Key words Eosinophilia-myalgia syndrome ; L-Tryptophan ; 3-(Phenylamino) alanine ; Rat ; 1 ; 1’-Ethylidenebis (L-tryptophan)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Consumption of certain product lots of L-tryptophan (LT) has been reported to be epidemiologically associated with an outbreak of eosinophilia-myalgia syndrome (EMS) in the United States. Since the production lots were found to contain 3-phenylamino alanine (PAA) as an impurity, its effects were studied by administering the substance orally by gavage to 5-week-old Sprague-Dawley rats. Groups of animals were given PAA for 13 consecutive weeks at dose levels of 1, 10 and 100 mg/kg per day. The animals were killed at 4 or 8 weeks. Hematological and blood biochemical tests were performed and detailed histopathological observations were made. No significant abnormalities were observed in the test animals and in particular no EMS-like conditions. A brief summary of other animal studies using several species of rats and mice performed in our laboratory since 1989 on various LT related substances is also presented. No EMS-like effects were observed in these studies.
    Type of Medium: Electronic Resource
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