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  • Articles  (8)
  • Nature Publishing Group  (7)
  • The American Society for Microbiology (ASM)  (1)
  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 128 (1931), S. 639-639 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] As is well known, the chemical evidence regarding the structure of the azides is far from being unambiguous, and four formulas have been proposed,1,2,3 ... Of these, 2 is ruled out because the central nitrogen atom would have a shared decet of valency electrons, which, for an ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 217 (1968), S. 380-381 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Recently we have been able to study the associations between C. tricolor Lesueur and D. venosus (H. M. Edwards) in the Caribbean, and C. polypus Forskal and D. gemmatus (H. M. Edwards) at Hawaii. C. tricolor showed a response to shells that was similar to C. parasitica that is, it could transfer to ...
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 164 (1949), S. 1050-1050 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE electric dipole moments of the α- and β-salicylides (assumed to be disalicylides) were found to be 6.27 and 2.42 D. respectively in benzene solution. The solutions showed no change of polarization with time. The former, being definitely a disalicylide, may therefore be given the cis ...
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 130 (1932), S. 314-315 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We have recently determined the total and the electron polarisations (the latter as the molecular refractivity for the mercury green line 5461) of nickel carbonyl in carbon tetrachloride solution at 0° C., and found values of 39.5 c.c. and 37.3 c.c. respectively. The latter value is somewhat ...
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 156 (1945), S. 601-602 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN a recent letter, Burawoy1 remarked that the ethane-like structure ascribed by us2 to the dimeric form of aluminium trimethyl from electron diffraction investigations, and supported by Brockway and Davidson3, is most unlikely. He proposed an ...
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 256 (1975), S. 64-66 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Polyacrylamide gel profiles of 32P-labelled RNA from C. thermosaccharolyticum exhibit an extra band that corresponds to an RNA species of about 160 nucleotides. The new species plus the normal 5S RNA together exist in approximate unit mole ratio to the 16S and 23S rRNAs. The new species is indeed ...
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 162 (1948), S. 104-104 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE electric dipole moments, in benzene solution at 25° C., of the following nuclear methylated styrenes have been measured: ... These values are approximately corrected for atom polarization. Otto and Wenzke1 report a value of 0.63 D for (I). The others appear not to have been ...
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  • 8
    Publication Date: 2018-04-27
    Description: Pseudomonas aeruginosa plays a major role in many chronic infections. Its ability to readily form biofilms contributes to its success as an opportunistic pathogen and its resistance/tolerance to antimicrobial/antibiotic therapy. A low-molecular-weight alginate oligomer (OligoG CF-5/20) derived from marine algae has previously been shown to impair motility in P. aeruginosa biofilms and disrupt pseudomonal biofilm assembly. As these bacterial phenotypes are regulated by quorum sensing (QS), we hypothesized that OligoG CF-5/20 may induce alterations in QS signaling in P. aeruginosa . QS regulation was studied by using Chromobacterium violaceum CV026 biosensor assays that showed a significant reduction in acyl homoserine lactone (AHL) production following OligoG CF-5/20 treatment (≥2%; P 〈 0.05). This effect was confirmed by liquid chromatography-mass spectrometry analysis of C 4 -AHL and 3-oxo-C 12 -AHL production (≥2%; P 〈 0.05). Moreover, quantitative PCR showed that reduced expression of both the las and rhl systems was induced following 24 h of treatment with OligoG CF-5/20 (≥0.2%; P 〈 0.05). Circular dichroism spectroscopy indicated that these alterations were not due to steric interaction between the AHL and OligoG CF-5/20. Confocal laser scanning microscopy (CLSM) and COMSTAT image analysis demonstrated that OligoG CF-5/20-treated biofilms had a dose-dependent decrease in biomass that was associated with inhibition of extracellular DNA synthesis (≥0.5%; P 〈 0.05). These changes correlated with alterations in the extracellular production of the pseudomonal virulence factors pyocyanin, rhamnolipids, elastase, and total protease ( P 〈 0.05). The ability of OligoG CF-5/20 to modify QS signaling in P. aeruginosa PAO1 may influence critical downstream functions such as virulence factor production and biofilm formation.
    Print ISSN: 0066-4804
    Electronic ISSN: 1098-6596
    Topics: Biology , Medicine
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