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  • Age-specific incidence  (1)
  • 1
    ISSN: 1572-9249
    Keywords: Age-specific incidence ; basic reproduction number ; epidemiology ; smoothing splines ; Weibull survival distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The nonparametric maximum likelihood estimator for current-status data has been known for at least 40 years, but only recently have the mathematical-statistical properties been clarified. This note provides a case study in the important and often studied context of estimating age-specific immunization intensities from a seroprevalence survey. Fully parametric and spline-based alternatives (also based on continuous-time models) are given. The basic reproduction number R 0 exemplifies estimation of a functional. The limitations implied by the necessarily rather restrictive epidemiological assumptions are briefly discussed.
    Type of Medium: Electronic Resource
    Signatur Availability
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