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  • DKFZ Publication Database  (1)
  • BONE-STRUCTURE  (1)
  • C-arm CT  (1)
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  • DKFZ Publication Database  (1)
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    Keywords: REPRODUCIBILITY ; COMPUTED-TOMOGRAPHY ; POSTMENOPAUSAL WOMEN ; MECHANICAL-PROPERTIES ; FUNDAMENTAL PRINCIPLES ; BONE-STRUCTURE ; C-arm CT ; DISTAL RADIUS ; FINITE-ELEMENT ; Flat-panel volume CT (fpVCT) ; FRACTURE RISK ; HYPOGONADAL MEN ; Multi-detector CT (MDCT) ; Trabecular structure
    Abstract: Purpose This paper assesses interscan, interreader, and intrareader variability of C-arm CT and compares it to that of flat-panel volume-CT (fpVCT) and high-definition multi-detector-CT (HD-MDCT). Methods Five cadaver knee specimens were imaged using C-arm-CT, fpVCT, and HD-MDCT. Apparent (app.) trabecular bone volume fraction (BV/TV), app. trabecular number (TbN), app. trabecular spacing (TbSp), and app. trabecular thickness (TbTh) of the proximal tibia were measured by three readers. Interreader, intrareader, and interscan variability for C-arm CT was expressed as coefficient of variation (CV), standard deviation (SD), and intraclass correlation coefficient (ICC). Results With the exception of app.TbSp (CV: 7.05-9.35%, SD: 0.06-0.09, ICC: 0.89-0.94), the variability of C-arm CT was low (CV: 2.41-6.43%, SD: 0.01-0.048, ICC: 0.65-0.98). Its interreader reliability (CV: 2.66-4.55%, SD: 0.01-0.03, ICC: 0.81-0.95) was comparable to that of HD-MDCT (CV: 2.41-4.08%, SD: 0.014-0.016, ICC: 0.95-0.96), and fpVCT (CV: 3.13-5.63%, SD: 0.009-0.036, ICC: 0.64-0.98) for all parameters except app.TbSp. Conclusions C-arm CT is a reliable method for assessing trabecular bone architectural parameters with the exception of app.TbSp due to spatial resolution limitation
    Type of Publication: Journal article published
    PubMed ID: 20658286
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