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  • 1
    Keywords: Medicine ; Neurosciences ; Bioinformatics ; Neurobiology ; Biomedicine ; Neurosciences ; Computational Biology/Bioinformatics ; Neurobiology ; Springer eBooks
    Description / Table of Contents: Part I. Non-invasive Brain-Computer Interface -- Chapter 1. Future directions for brain-machine interfacing technology -- Chapter 2. Brain-Computer Interface for Smart Vehicle: Detection of Braking Intention during Simulated Driving -- Chapter 3. Benefits and limits of multimodal neuroimaging for Brain Computer Interfaces -- Chapter 4. Multifrequency Analysis of Brain-Computer Interfaces -- Part II. Cognitive- and Neural-rehabilitation Engineering -- Chapter 5. Current Trends in Memory Implantation and Rehabilitation -- Chapter 6. Moving Brain Controlled Devices Outside the Lab: Principles and Applications -- Part III. Big Data Neurocomputing -- Chapter 7. Across cultures: a Cognitive and Computational Analysis of Emotional and Conversational Facial Expressions in Germany and Korea -- Chapter 8. Bottom-Up Processing in Complex Scenes: a unifying perspective on segmentation, fixation saliency, candidate regions, base-detail decomposition, and image enhancement -- Chapter 9. Perception-based motion cueing: a Cybernetics approach to motion simulation -- Chapter 10. The other-race effect revisited: no effect for faces varying in race only -- Part IV. Early Diagnosis and Prediction of Neural Diseases -- Chapter 11. Functional neuromonitoring in acquired head injury -- Chapter 12. Diagnostic Optical Imaging Technology and its Principles -- Chapter 13. Detection of Brain Metastases using Magnetic Resonance Imaging -- Chapter 14. Deep Learning in Diagnosis of Brain Disorders
    Abstract: Brain and Cognitive Engineering is a converging study field to derive a better understanding of cognitive information processing in the human brain, to develop ́€œhuman-lik逝 and neuromorphic artificial intelligent systems and to help predict and analyze brain-related diseases. The key concept of Brain and Cognitive Engineering is to understand the Brain, to interface the Brain, and to engineer the Brain. It could help us to understand the structure and the key principles of high-order information processing on how the brain works, to develop interface technologies between a brain and external devices and to develop artificial systems that℗ can ultimately mimic human brain functions. The convergence of behavioral, neuroscience and engineering research could lead us to advance health informatics and personal learning, to enhance virtual reality and healthcare systems, and to ́€œreverse engineeŕ€ some brain functions and build cognitive robots. In this book, four different recent research directions are presented: Non-invasive Brain-Computer Interfaces, Cognitive- and Neural-rehabilitation Engineering, Big Data Neurocomputing, Early Diagnosis and Prediction of Neural Diseases. We cover numerous topics ranging from smart vehicles and online EEG analysis, neuroimaging for Brain-Computer Interfaces, memory implantation and rehabilitation, big data computing in cultural aspects and cybernetics to brain disorder detection. Hopefully this will provide a valuable reference for researchers in medicine, biomedical engineering, in industry and academia for their further investigations and be inspiring to those who seek the foundations to improve techniques and understanding of the Brain and Cognitive Engineering research field
    Pages: XI, 213 p. 73 illus., 56 illus. in color. : online resource.
    Edition: 1st ed. 2015.
    ISBN: 9789401772396
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  • 2
    Keywords: Medicine ; Human Genetics ; Bioinformatics ; Biomedicine ; Human Genetics ; Bioinformatics ; Biomedicine general ; Springer eBooks
    Description / Table of Contents: Part I: Overview.-℗ History of DNA Sequencing Technologies -- Clinical Molecular Diagnostic Techniques: A Brief Review -- Part II: The Technologies and Bioinformatics -- Methods of Gene Enrichment and Massively Parallel Sequencing Technologies -- Sequence Alignment, Analysis, and Bioinformatics Pipelines -- Protein Structural Based Analysis for Variant Interpretation of Missense Variants at the Genomics Era: Using MNGIE Disease as an Example -- Algorithms and Guidelines for Interpretation of DNA Variants -- Part III: Application to Clinical Diagnostics -- NGS-based Clinical Diagnosis of Genetically Heterogeneous Disorders -- Molecular Diagnosis of Congenital Disorders of Glycosylation (CDG) -- NGS Improves the Diagnosis of X-Linked Intellectual Disability (XLID) -- NGS Analysis of Heterogeneous Retinitis Pigmentosa -- Next Generation Sequencing of the Whole Mitochondrial Genome -- Application of Next-Generation Sequencing of Nuclear Genes for Mitochondrial Disorders -- Noninvasive Prenatal Diagnosis Using Next Generation Sequencing -- Part IV: Compliance with CAP/CLIA Regulations -- Guidelines and Approaches to Compliance with Regulatory and Clinical Standards: Quality Control Procedures and Quality Assurance -- Validation of NGS-based Test and Implementation of Quality Control Procedures -- Frequently Asked Questions about the Clinical Utility of Next Generation Sequencing in Molecular Diagnosis of Human Genetic Diseases -- Index
    Abstract: In recent years, owing to the fast development of a variety of sequencing technologies in the post human genome project era, sequencing analysis of a group of target genes, entire protein coding regions of the human genome, and the whole human genome has become a reality.℗ ℗ Next Generation Sequencing (NGS) or Massively Parallel Sequencing (MPS) technologies offers a way to screen for mutations in many different genes in a cost and time efficient manner by deep coverage of the target sequences.℗ This novel technology has now been applied to clinical diagnosis of Mendelian disorders of well characterized or undefined diseases, discovery of new disease genes, noninvasive prenatal diagnosis using maternal blood, and population based carrier testing of severe autosomal recessive disorders.℗ This book covers topics of these applications, including potential limitations and expanded application in the future.℗ ℗ ℗ ℗
    Pages: : digital.
    ISBN: 9781461470014
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  • 3
    Dordrecht : Springer
    Keywords: Medicine ; Gene Expression ; Biotechnology ; Genetic Engineering ; Bioinformatics ; Biological models ; Microbial genetics ; Biomedicine ; Gene Expression ; Systems Biology ; Biotechnology ; Microbial Genetics and Genomics ; Genetic Engineering ; Computational Biology/Bioinformatics ; Springer eBooks
    Pages: : digital.
    ISBN: 9789400745346
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