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  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 6 (1988), S. 690-694 
    ISSN: 0736-0266
    Keywords: Growth cartilage cell ; In vitro ; Direct curret stimulation ; Proteoglycan synthesis ; DNA synthesis ; Callus cell ; Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Cultured growth cartilage cells of young rabbits were stimulated by three levels(10, l and 0.l μA) of constant direct current (DC). The effect of DC was examined by measuring the activities of proteoglycan synthesis (uptake of [35S]sodium sulfate and toluidine blue staining) and DNA synthesis (uptake of [3H]thymidine). DC increased syntheses of both proteoglycans and DNA when l μA calculated curren densiy of l μA/cm2 was applied for 3 days. A longer stimulation resulted in a larger difference between stimulated and unstimulted cells. Ten-microampere stimulation devitalized the cells, while 0.l μA had no effect on cell activities.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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