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  • 1
    Keywords: Bioinformatics ; Microbiology ; Biomedical Engineering ; Bioinformatics ; Microbiology ; Biomedical Engineering/Biotechnology ; Springer eBooks
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: DNA sequence assembly and annotation of genes -- Chapter 3: Databases and protein structures -- Chapter 4: Pair-wise alignment, multiple alignment and BLAST -- Chapter 5: Primer design -- Chapter 6: Short introduction to phylogenetic analysis of molecular sequence data -- Chapter 7: Sequence based classification and identification of prokaryotes -- Chapter 8: 16S rRNAampliconsequencing for metagenomics -- Chapter 9: Full DNA metagenomics -- Chapter 10: Transcriptomics -- Chapter 11: Molecular typing of prokaryotes
    Abstract: This textbook introduces to the basic concepts of bioinformatics and enhances students’ skills in using software and tools relevant for investigations in microbiology. The most relevant methods to analyze data are shown and readers are introduced on how to draw valid conclusions based on the results obtained. Software and servers which are free to use on the internet are presented and more advanced stand-alone programs are suggested as a second option. Exercises and training quizzes are provided at the end of each chapter to facilitate learning. The book targets Ph. D. students and advanced undergraduates in microbiology, biotechnology, and (veterinary) medicine with little to basic knowledge in bioinformatics
    Pages: X, 213 p. 105 illus. in color. : online resource.
    ISBN: 9783319992808
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  • 2
    ISSN: 1530-0358
    Keywords: Collagen ; Colon ; Growth hormone ; Healing ; Scanning electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: This experimental study was designed to investigate the collagen fibrils of colonic anastomoses in rats and to compare normal healing with rats treated with biosynthetic growth hormone (bGH). METHODS: The healing zone of left colonic anastomoses was studied at days 2, 4, and 6 after surgery by means of scanning electron microscopy. RESULTS: After four days of healing a normal anastomosis was filled with loosely packed and unorganized collagen fibrils, which were organized into collagen fibers after six days. Compared with normal anastomoses, rats treated with bGH showed a more organized healing, characterized by a dense structure of a new-formed collagen framework of fibrils and immature collagen fibers after four days and with bundles of new collagen fibers after six days. CONCLUSIONS: Healing colonic anastomoses are characterized by new-formed collagen fibrils at postoperative day 4, and bGH seems to stimulate structural organization of the anastomotic collagen fibrils into fibers.
    Type of Medium: Electronic Resource
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