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  • Guinea pig  (1)
  • Man  (1)
  • 1980-1984  (2)
  • 1
    ISSN: 1432-0568
    Keywords: Pars cerebellaris loci coerulei ; Man ; Neuronal loss ; Aging ; Biomathematical analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pars cerebellaris loci coerulei is a flat accumulation of perikarya representing a subnucleus of the locus coeruleus in the roof of the fourth ventricle of the brain in man. A quantitative study was done on this subnucleus; it comprised 67 specimens from individuals between 11 and 90 years. Nerve cell counts were performed on cleared mounted block preparations. Mathematical analysis of the data was performed using logistic growth functions. The results showed that with advancing age there is a loss of neurons in both sexes. This begins in the female approximately after age 40; in the male already at age 20 (reaching a lower value in old age). The final loss of neurons is more pronounced in the male than in the female. Male and female specimens did not differ in the total number of neurons. In both sexes the left side of the pars cerebellaris loci coerulei contained more neurons than the right.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 162 (1981), S. 81-103 
    ISSN: 1432-0568
    Keywords: Cytoarchitectonics ; Guinea pig ; Iso- and Allocortex ; Cortical mapping ; Automatic measuring method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The cerebral cortex of the guinea pig has been examined by means of a quantitative cytoarchitectonic method (Schleicher et al. 1978; Zilles et al. 1978a). In this method, a computer-controlled automatic image analyzer determines the grey level index of microscopic fields measuring 50x50 μm in Nissl-stained sections by a systematic scanning procedure. Computer plots of serially sectioned histological slides from three hemispheres were produced by printing selected ranges of grey level indices. The delineation of cortical areas was worked out in these plots based on quantitative criteria. Cortical maps of the areal pattern were reconstructed graphically. The resulting cortical map of the guinea pig differes from that of Rose (1912), but it corresponds to the results of Friede (1960) and is in agreement with neurophysiological studies. In general, the areal pattern of the guinea pig is similar to that of the rat (Zilles et al. 1980), but there are also some differences. These differences are discussed with respect to functional considerations.
    Type of Medium: Electronic Resource
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