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  • 1
    Electronic Resource
    Electronic Resource
    ISSN: 1573-6881
    Keywords: Potassium channels ; membrane proteins ; channel gating ; ion permeation ; mutagenesis ; channel structure ; shaker ; TEA ; charybdotoxin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Physics
    Notes: Abstract The voltage-activated K+ channels are members of an ion channel family that includes the voltage-activated Na+ and Ca2+ channels. These ion channels mediate the transmembrane ionic currents that are responsible for the electrical signals produced by cells. The recent cloning of numerous voltage-activated K+ channels has made it possible to combine molecular-genetic and biophysical methods to study K+ channel mechanisms. These mutagenesis-function studies are beginning to provide new information about the architecture of K+ channel proteins and how they form a voltage-gated, K+-selective pore.
    Type of Medium: Electronic Resource
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