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  • Carnitine  (1)
  • Immune competence  (1)
  • Qualitätskontrolle  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 14 (1986), S. 241-246 
    ISSN: 1434-0879
    Keywords: Seminal fluid ; Biochemical analysis ; Citrate ; Fructose ; Carnitine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The measurement of biochemical markers in human seminal plasma is important in the evaluation of male infertility. We recommend the measurement of one representative substance for each organ involved in seminal fluid production as a routine diagnostic tool: The initial fructose level for seminal vesicular function, citrate or acid phosphatase for the prostate gland and free carnitine as an index of epididymal function. A biochemical analysis of seminal fluid enables us to detect disturbances of the male adnexal organs and may lead to more exact therapy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Reproduktionsmedizin 14 (1998), S. 224-231 
    ISSN: 1434-808X
    Keywords: Schlüsselwörter Ejakulatanalyse ; Fertilität ; männliche ; Testverfahren ; Qualitätskontrolle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Die Ejakulatanalyse stellt eine der wichtigsten Untersuchungen zur Erfassung des männlichen Fertilitätsstatus dar. Durch die makroskopische und mikroskopische Bewertung und durch Anwendung biochemischer Nachweisverfahren zur Charakterisierung der Zusammensetzung des Seminalplasmas läßt sich eine Klassifikation der Ejakulatqualität vornehmen. Es gibt verschiedene Klassifikationssysteme, die sich vor allem durch die unterschiedliche Beurteilung der Spermienmorphologie unterscheiden. Am gebräuchlichsten sind die von der Weltgesundheitsorganisation empfohlenen Richtlinien zur Analyse des menschlichen Ejakulats und der Spermien/Zervixschleim-Interaktion (WHO 1992). Mit Hilfe spezieller Funktionstests lassen sich Partialfunktionen der Spermien erfassen, allerdings ist die prognostische Aussagekraft dieser Testverfahren begrenzt. Trotz großer Bemühungen um eine standardisierte Untersuchungstechnik kommt es durch unvermeidbare subjektive Einflußfaktoren zu einer z. T. ausgeprägten Befundvariabilität zwischen verschiedenen andrologischen Laboratorien. Die Problem der internen und externen Qualitätskontrolle im andrologischen Labor ist bisher nur unzureichend gelöst.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1335
    Keywords: Whole blood cell cultures ; Cytokine production ; Urogenital carcinomas ; Immune competence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The production of the cytokines interferon γ (IFN γ), interleukin-1 α (IL-1 α) and tumor necrosis factor α (TNF α) was investigated in the mitogen-stimulated whole blood cell culture media from 51 patients with urinary bladder carcinomas, 52 patients with renal carcinomas, 31 patients with prostatic carcinomas and 360 healthy controls. The cytokines were measured 4 days after induction by a sensitive enzymo-immunological assay. In the blood cell culture supernatants of the patients with urinary bladder carcinomas significancy lower levels of IFN γ (P≤0.001), IL-2 (P≤0.001) and TNFα (P≤0.05) were found as compared to the controls. Blood cells of patients with renal carcinomas had lower production of IFN γ (P≤0.01), IL-2 (P≤0.001) and IL-1α (P≤0.01), whereas the values of the total group of patients with prostatic carcinomas were not significantly different from those of the controls. Lymphocyte and monocyte counts were almost identical in the control and all tumor patient groups. When the patients with renal carcinomas and prostatic carcinomas were analyzed according to their different clinical stages we could show a gradual depression of the IFN-γ levels, which was related to tumor burden.
    Type of Medium: Electronic Resource
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