Head and neck cancer
Springer Online Journal Archives 1860-2000
Abstract To evaluate the efficacy of radiation therapy for pain relief of bone metastases from head and neck cancer, a total of 22 patients with head and neck cancer with 30 metastatic bone lesions treated by radiation therapy at the Cancer Institute Hospital were analyzed. These patients were given a dose of 20 to 50 Gy in 10 to 25 fractions using liniac X-ray or electron beam and were divided into two groups. Group A consisted of 10 patients with tongue cancer (tongue cancer group), and group B consisted of 12 patients other than with tongue cancer (non-tongue cancer group). In group A, of the 6 metastatic lesions treated with over 30 Gy, 17% achieved CR (complete pain relief for more than 3 months), 33% showed PR (over 50% extent pain relief), and 50% NC. While, in group B, of the 17 lesions 35% showed Cr, 53% PR and 12% NC. There was a significant difference in the response rate (50% vs 88%, P〈0.01) of pain relief between the osseous metastases from tongue cancer group and the non-tongue cancer group, although further prospective studies are necessary to elucidate the radiosensitivity of bone metastases in terms of the histologic difference in head and neck cancer patients.
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