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  • 1
    ISSN: 1433-0385
    Keywords: Key words: Liver transplantation ; Quality ; Results ; Small centre. ; Schlüsselwörter: Orthotope Lebertransplantation ; Qualität im kleinen Zentrum ; Langzeitergebnisse.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Die orthotope Lebertransplantation ist heute zur Therapie der Wahl der Endstadien verschiedener Lebererkrankungen geworden. International beträgt das perioperative Überleben 80 % und die 5-Jahres-Überlebensrate liegt bei elektiv operierten nicht malignen Erkrankungen über 70 %. Das Lebertransplantationsprogramm in Bern ist im internationalen Vergleich klein und basiert auf dem Routinebetrieb einer Universitätsklinik. Es stellt sich daher die Frage nach den Resultaten und der Daseinsberechtigung eines solchen Programms. Im Zeitraum von 66 Monaten wurden am Inselspital in Bern 62 Lebertransplantationen bei 60 Patienten durchgeführt. Die perioperative Letalität betrug 3,3 %, die 30-Monats-Überlebensrate 92 % (elektive Patienten mit benignen Erkrankungen). 68 % der Patienten sind im Median 30 Monate nach der Transplantation arbeitsfähig und 83 % unabhängig von fremder Hilfe. Diese Resultate über einen 5-Jahres-Zeitraum sind vergleichbar mit den Ergebnissen internationaler Transplantationszentren. Aus unserer Sicht hat ein solches kleines Programm daher, wenn es interdisziplinär im Konzept einer Universitätsklinik eingepaßt ist, Daseinsberechtigung und Perspektive.
    Notes: Summary. Today, orthotopic liver transplantation is the treatment of choice for the end-stage of various liver diseases, and a 1-year survival rate of 80 % and a 5-year survival rate of 70 % in elective patients without tumor are reported in international surveys. The liver transplant programme of the Inselspital in Bern is small compared with international centres, which may raise questions about the results and the justification for such a programme. Over a period of 66 months, 62 liver transplantations were performed in 60 patients at the Inselspital. The hospital mortality was 3.3 %, and the 2.5-year overall survival rate was 92 % for elective cases without tumor. After a median follow-up of 30 months, 68 % of all patients were re-integrated in housework or full- or part-time in their profession, and 83 % were independent from the help of others. We conclude that a small liver transplant programme based only on routine resources can achieve results comparable to the international standards.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-2622
    Keywords: Age-related macular degeneration ; Long-term follow-up ; Low vision aids ; Low vision rehabilitation ; Reading frequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract One to five years after successful low vision rehabilitation, 199 patients with agerelated macular degeneration were asked by means of a questionnaire whether they still used their low vision aids and whether they were satisfied with the low vision counceling. We received feedback from 66% of the patients. 20 patients had already passed away. 74% of the 112 answering patients still use a low vision aid today. Three-quarters of them still use the originally prescribed low vision aid. Interestingly enough, the daily reading time was rather short, only 16% of the patients read more than 1 hour per day, 42% read somewhat more and 13% somewhat less than 10 minutes per day. Retrospectively, 81% of all responding patients found their low vision counceling at least a little, more of them quite or very helpful. These numbers suggest, that the initial labor of patiently examining and training older, visually handicapped patients is worthwhile.
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  • 3
    ISSN: 0005-2736
    Keywords: (Mouse lymphoma cell) ; Adriamycin ; Drug action ; Lipid composition ; Membrane fluidity ; Membrane permeability ; Mitomycin C
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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