Springer Online Journal Archives 1860-2000
Abstract For many years, the known vascular complications in Behçet's disease have been attributed to thrombophlebitis, but considerable number of reports has been published in recent years relating to cases with aneurysm and arterial occlusion. We experienced arterial involvements in 6 cases with Behçet's disease up to date. In five, the histological findings of the resected specimens suggested a presence of angiitis derived from the media. Of the vascular changes in Behçet's disease, aneurysm develops relatively in early age of life and is extremely prone to rupture. Therefore, an aggressive surgical approach is mandatory for aneurysm, as soon as the diagnosis of this disease becomes definite. Histological changes of these arteries revealed derangements of the media, particularly of its elastic fibers. Although it is difficult to draw a conclusion at this stage that angiitis is one of the etiological factors of Behçet's disease, etiologic relation of these angiitic changes of unknown origin is discussed from various standpoints of view.
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