CaRLO — Cancer Research Library Online

Hits per page

hits 1 - 2 | 2 hits

Sorting

Electronic Resource

Central neural control of pineal melatonin synthesis in rat (1987)

Møller, M. ; Reuss, S. ; Olcese, J. ; [et al.]

Springer

Cellular and molecular life sciences 43 (1987), S. 186-188

add to mindlist on the mindlist

Details

ISSN: 1420-9071

Keywords: Central innervation ; melatonin synthesis ; pineal gland ; rat

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary To investigate a possible central neural influence on nocturnal pineal metabolic activity, frontal transsections of the stria medullaris thalami were conducted. Enzymes involved in melatonin synthesis, i.e. N-acetyltransferase and hydroxyindole-O-methyl-transferase, exhibited reduced activities in operated animals when compared to controls. These results indicate a modulatory role of central structures on noctural pineal indole metabolism.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01942845

Permalink

Signatur	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

Electronic Resource

Effects of melatonin on spontaneous electrical activity of neurons in rat suprachiasmatic nuclei: an in vitro iontophoretic study (1989)

Stehle, J. ; Vanecek, J. ; Vollrath, L.

Springer

Journal of neural transmission 78 (1989), S. 173-177

add to mindlist on the mindlist

Details

ISSN: 1435-1463

Keywords: SCN neurons ; circadian rhythm ; iontophoresis ; melatonin receptors

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Circadian rhythms, endogenously generated in suprachiasmatic nuclei (SCN), seem to be under the direct influence of melatonin. Therefore, the effect of iontophoretically applied melatonin on electrical activity of SCN neurons was investigated in vitro. Usually, melatonin had an inhibitory effect. In the 3-h periods before (2.00–5.00 p.m.) or after (5.00–8.00 p.m.) the light-dark transition the percentage of SCN neurons sensitive to melatonin was very high (80% and 100%, respectively). However, efficacy of melatonin was low in the periods preceeding (20%) and following (33%) this 6-h time interval.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01252503

Permalink

Signatur	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

hits 1 - 2 | 2 hits