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  • 1
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Kongress Medizin und Gesellschaft 2007; 20070917-20070921; Augsburg; DOC07gmds846 /20070906/
    Publication Date: 2007-09-07
    Keywords: Berufsklasse ; Herzkreislaufmortalität ; Body-Mass-Index ; ddc: 610
    Language: German
    Type: conferenceObject
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  • 2
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    German Medical Science; Düsseldorf, Köln
    In:  50. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 12. Jahrestagung der Deutschen Arbeitsgemeinschaft für Epidemiologie; 20050912-20050915; Freiburg im Breisgau; DOC05gmds197 /20050908/
    Publication Date: 2005-09-09
    Keywords: ddc: 610
    Language: German
    Type: conferenceObject
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  • 3
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    German Medical Science; Düsseldorf, Köln
    In:  Kooperative Versorgung - Vernetzte Forschung - Ubiquitäre Information; 49. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 19. Jahrestagung der Schweizerischen Gesellschaft für Medizinische Informatik (SGMI) und Jahrestagung 2004 des Arbeitskreises Medizinische Informatik (ÖAKMI) der Österreichischen Computer Gesellschaft (OCG) und der Österreichischen Gesellschaft für Biomedizinische Technik (ÖGBMT); 20040926-20040930; Innsbruck; DOC04gmds140 /20040914/
    Publication Date: 2004-09-14
    Keywords: ddc: 610
    Language: English
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  • 4
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Kongress Medizin und Gesellschaft 2007; 20070917-20070921; Augsburg; DOC07gmds754 /20070906/
    Publication Date: 2007-09-07
    Keywords: Kaplan-Meier estimator ; tie survivor estimator ; discrete survival times ; ties ; Greenwood variance estimator ; ddc: 610
    Language: German
    Type: conferenceObject
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  • 5
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Kongress Medizin und Gesellschaft 2007; 20070917-20070921; Augsburg; DOC07gmds318 /20070906/
    Publication Date: 2007-09-07
    Keywords: ddc: 610
    Language: English
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  • 6
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Mainz//2011; 56. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 6. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi); 20110926-20110929; Mainz; DOC11gmds195 /20110920/
    Publication Date: 2011-09-20
    Keywords: metabolic factors ; cervical cancer ; prospective ; ddc: 610
    Language: English
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  • 7
    ISSN: 1432-1076
    Keywords: Cytostatic heart disease in children ; Adriamycin ; Systolic time intervals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a prospective study, 44 children receiving Adriamycin (ADR) for various neoplastic diseases underwent serial estimations of the systolic time intervals (STI) for the noninvasive assessment of left ventricular myocardial performance. Five of the 44 children developed clinical signs of ADR-related congestive heart failure at a cumulative dose of less than 550 mg/m2 body surface area. Clinical symptoms, changes in the electrocardiogram and in the chest X-ray were preceded in every case by changes of the STI, mainly a prolongation of the left ventricular pre-ejection period (PEP), or a decrease of the ejection time (ET)/pre-ejection period (PEP) ratio (ET/PEP). A continous increase of the PEP and a decrease of the ET/PEP-ratio also gave an indication of myocardial dysfunction during ADR treatment in the other children without clinical signs of congestive heart failure. This subclinical cardiotoxic effect of ADR below the critical cumulative dose of 550 mg/m2 was observed in children with pre-existent myocardial damage, with preceding thoracic irradiation, or during concurrent chemotherapy, of which cyclophosphamide seemed to be most important. Thus, the estimation of the STI proved helpful and reliable in the early detection of incipient heart failure and in the selection of high risk patients in children receiving ADR treatment.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1076
    Keywords: Indomethacin ; Drug level monitoring ; Very low birth weight infants ; Ductus arteriosus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract First results are described of individually tailored indomethacin dose rates employing on-line drug level monitoring for pharmacologically induced ductal constriction in very low birth weight infants with symptomatic patent ductus arteriosus (sPDA). In addition prolonged indomethacin therapy was introduced. From our data it appears that the effective threshold indomethacin level for the induction of ductus constriction has to be about 1000 ng/ml 10 h postdosing, while ductus closure can be maintained with a dose rate that exceeds a plasma level of 500 ng/ml for at least 1 week. These maintenance levels were also effective in completely suppressing the urinary metabolite excretion rates of PGI2 and PGE2, which are potential mediators of ductal relaxation. On-line indomethacin level monitoring appears to be practically essential for prolonged indomethacin therapy to overcome the marked variation of indomethacin disposition in preterm infants with sPDA.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1076
    Keywords: Supraventricular tachycardia ; Cardioversion ; Chest thump ; Complications
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report on two cases of mechanical termination of supraventricular tachycardia by chest thump which were followed by serious complications. In a 3-year-old boy with an otherwise normal heart, incessant supraventricular tachycardia was converted to sinus rhythm by a single precordial thump. This, however was followed by thrombo-embolic infarction of the left-sided middle cerebral artery. In another case of a 9-year-old girl, recurrent episodes of supraventricular tachycardia were associated with Ebstein anomaly of the tricuspid valve. Chest thump was successful in terminating supraventricular tachycardia but induced a short run of ventricular tachycardia which terminated itself and was then followed by sinus rhythm. It is concluded that even a slight precordial thump implies undetermined risks in the acute management of supraventricular tachycardia in children and should therefore be abandoned in favour of other methods.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1433-0385
    Keywords: Keywords: Per- and subtrochanteric fracture – Gamma nail – Mobility – Complication. ; Schlüsselwörter: Per- und subtrochantäre Fraktur – Gammanagel – Mobilisation – Komplikation.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Einleitung: Ziel dieser retrospektiven Studie ist es, den Einfluß von Alter, Begleiterkrankungen, Frakturform, Operationszeitpunkt, Wahl des Implantats (kurzer oder langer Gammanagel) und Operationsverfahren auf Mobilisationsgrad, radiologischen Heilungsverlauf und mögliche Komplikationen nach operativer Stabilisierung von per- und subtrochantären Oberschenkelbrüchen mittels Gammanagel zu analysieren. Patienten und Methoden: Von 1992 bis 1997 wurden 96 Patienten mit isolierter per- oder subtrochantärer Oberschenkelfraktur mittels Gammanagel (Howmedica) operiert. Das Durchschnittsalter der Patienten zum Zeitpunkt der Verletzung betrug 72,5 (27–101) Jahre. 27 Patienten waren Männer, und 69 waren Frauen. Die Operation erfolgte durchschnittlich 1,19 (0–10) Tage nach dem Unfall. Die postoperativen Kontrollen erfolgten nach 3, 6 und 12 Monaten. Hierbei wurden jeweils Röntgenaufnahmen des Oberschenkels mit Hüftgelenk in 2 Ebenen durchgeführt und der Mobilisationsgrad der Patienten beurteilt. Ergebnisse: Begleiterkrankungen, Operationszeitpunkt, Frakturtyp, Operationsverfahren und Wahl des Implantats (kurzer oder langer Gammanagel) hatten keinen Einfluß auf den Grad der Mobilisation, auf den radiologischen Heilungsverlauf oder auf aufgetretene Komplikationen. Ältere Patienten ( 〉 70 Jahre) waren schlechter mobilisierbar (p 〈 0,001). Ein Jahr nach dem Unfall waren 97 % der Frakturen radiologisch geheilt. Bei 15 Patienten (18 %) kam es zu technischen Komplikationen bei der Verwendung des Gammanagels. Schlußfolgerungen: Per- und subtrochantäre Oberschenkelfrakturen können mit Hilfe des Gammanagels bei richtiger Handhabung stabil versorgt und die Patienten frühzeitig mobilisiert werden.
    Notes: Abstract. Background: From 1992 through 1997 96 patients with per- or subtrochanteric femur fractures were treated with a Gamma nail. We retrospectively evaluated the influence of patient age, additional diseases, type of fracture, time of operation, type of implant (short/long Gamma nail) and surgical approach (open/closed reduction) on the mobility of the patients, healing of the fractures on radiographs, and possible complications. Patients and methods: The average patient age was 72.5 years (range 27 to 101). There were 27 male and 69 female patients. Surgery was performed 1.19 (0–10) days after injury. At 3, 6, and 12 months after surgery radiographs of the involved hip joint and femur were obtained and the degree of mobility was assessed. Results: Additional diseases, type of fracture, time of operation, type of implant (short/long Gamma nail) and surgical approach (open/closed reduction) did not influence mobility of the patients, healing of the fractures on radiographs or rate of complications. It was more difficult to mobilize older patients (P 〈 0.001). After 1 year 97 % of all fractures had healed on radiographs. In 15 patients (18 %) complications occurred due to technical errors using the Gamma nail. Discussion: With the Gamma nail stable osteosynthesis of per- and subtrochanteric femur fractures is obtained independently of the fracture classification. Patients can be mobilized immediately. Technical errors must be avoided.
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