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Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin (2000)

Cropp, T. Ashton ; Wilson, Dennis J. ; Reynolds, K.A.

[s.l.] : Nature America Inc.

Nature biotechnology 18 (2000), S. 980-983

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] The side chain of the antifungal antibiotic ansatrienin A from Streptomyces collinus contains a cyclohexanecarboxylic acid (CHC)-derived moiety. This moiety is also observed in trace amounts of ω-cyclohexyl fatty acids (typically less than 1% of total fatty acids) produced by S. collinus. ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/79479

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Imaging Alzheimer's amyloid (2000)

Selkoe, Dennis J.

[s.l.] : Nature America Inc.

Nature biotechnology 18 (2000), S. 823-824

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Progress in deciphering the fundamental biological mechanism of Alzheimer's disease (AD) is proceeding at an impressive pace. A consensus has emerged among many investigators that cerebral accumulation of the amyloid β-protein (Aβ) represents an early and necessary step in pathogenesis ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/78422

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Navigating biotechnology's new fiscal opportunities (1998)

Purcell, Dennis J.

[s.l.] : Nature America Inc.

Nature biotechnology 16 (1998), S. 51-53

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Bioentrepreneurs who fashion strategies designed to meet the changing needs of the pharmaceutical industry and the institutional investment community are likely to find deep pockets for ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/5423

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