Springer Online Journal Archives 1860-2000
Chemistry and Pharmacology
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Summary As a new type of the nucleic acid analogs, poly-L-lysine derivatives containing adenine, thymine and uracil were prepared. By using the activated ester method, carboxyethyl derivatives of the nucleic acid bases were grafted onto poly-L-lysine. The thymine and uracil derivatives were completely substituted to poly-L-lysine. The content of adenine unit in the polymer, however, was less than that of the thymine analog.
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