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  • 1
    Keywords: Medicine ; Human Genetics ; Public Health ; Epidemiology ; Bioinformatics ; Biomedicine ; Human Genetics ; Computational Biology/Bioinformatics ; Public Health/Gesundheitswesen ; Epidemiology ; Springer eBooks
    Pages: : digital
    ISBN: 9781441914828
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  • 2
    Keywords: Medicine ; Human Genetics ; Public Health ; Epidemiology ; Bioinformatics ; Biochemistry ; Biomedicine ; Human Genetics ; Epidemiology ; Biochemistry, general ; Computational Biology/Bioinformatics ; Public Health ; Springer eBooks
    Description / Table of Contents: Introduction -- 1. Toward new tools -- 2. Models of development -- 3. Groupoid symmetries -- 4. Epigenetic catalysis -- 5. Developmental disorders -- 6. An interim perspective -- 7. The obesity pandemic in the US -- 8. Coronary heart disease in the US. - 9. Cancer: a developmental perspective -- 10. Autoimmune disorders -- 11. Demoralization and obesity in Upper Manhattan -- 12. Death at an early age: AIDS and related mortality in New York City -- 13. Mental Disorders I: Western atomism and its culture-bound syndromes -- 14. Mental Disorders II: Psychopathology and sleep -- 15. Diabetes and Thyroid Cancer in Manhattan's Chinatown -- 16. Right-To-Work Laws and Alzheimer's Disease -- 17. Stress as an Environmental Exposure -- 18. Final Thoughts -- 19. Mathematical Appendix
    Abstract: This book describes how epigenetic context, in a large sense, affects gene expression and the development of an organism, using the asymptotic limit theorems of information theory to construct statistical models useful in data analysis. The approach allows deep understanding of how embedding context affects development. We find that epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. In sum, environmental stressors can induce a broad spectrum of developmental dysfunctions, and the book explores a number of pandemic chronic diseases, using U.S. data at different scales and levels of organization. In particular, we find the legacy of slavery has been grossly compounded by accelerating industrial decline and urban decay. Individual chapters are dedicated to obesity and its sequelae, coronary heart disease, cancer, mental disorders, autoimmune dysfunction, Alzheimer’s disease, and other conditions. Developmental disorders are driven by environmental factors channeled by historical trajectory and are unlikely to respond to medical interventions at the population level in the face of persistent individual and community stress. Drugs powerful enough to affect deleterious epigenetic programming will likely have side effects leading to shortened lifespan. Addressing chronic conditions and developmental disorders requires significant large-scale changes in public policy and resource allocation
    Pages: XIII, 344 p. 52 illus. : online resource.
    Edition: 2nd ed. 2017.
    ISBN: 9783319480787
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  • 3
    Unknown
    Champaign, Ill : Project Gutenberg
    Keywords: Russia, Description and travel.
    ISBN: 0-585-01713-1
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  • 4
    Unknown
    Raleigh, N.C : Alex Catalogue
    Keywords: Jesus Christ, Fiction.
    ISBN: 0-585-05262-X
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  • 5
    Unknown
    New York : Oxford University Press
    Keywords: Wesley, Susanna Annesley,, 1669-1742. ; Wesley, Susanna Annesley,, 1670-1742. ; Anglicans, England, Biography.
    Pages: xiv, 504 p.
    ISBN: 0-585-24572-X
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  • 6
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    Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press
    Call number: B110:138
    Keywords: Aging / physiology ; Aging / genetics ; Cell Aging / physiology ; Molecular Biology
    Description / Table of Contents: The human mitochondrion and pathophysiology of aging and age-related diseases / D.C. Wallace -- Sirtuins : a universal link between NAD, metabolism, and aging / S. Imai and L.P. Guarente -- Calorie restriction in lower organisms / S.L. Helfand, J.H. Bauer, and J.G. Wood -- Evolutionary theory in aging research / S.N. Austad and T.B.L. Kirkwood -- An overview of the biology of aging : a human perspective / G.M. Martin and C.E. Finch -- P53, cancer, and longevity / L.A. Donehower and A.J. Levine -- Aging processes in caenorhabditis elegans / H.A. Tissenbaum and T.E. Johnson -- Cellular senescence : a link between tumor suppression and organismal aging? / J.M. Sedivy, U.M. Munoz-Najar, J.C. Jeyapalan, and J. Campisi -- Genome-wide views of aging gene networks / S.K. Kim -- Aging in mammalian stem cells and other self-renewing compartments / D.J. Rossi and N.E. Sharpless -- Yeast, a feast : the fruit fly Drosophila as a model organism for research into aging / L. Partridge and J. Tower -- DNA repair and aging / V.A. Bohr ... [et al.] -- Extended life span in mice with reduction in the GH/IGF-1 axis / J.J. Kopchick, A. Bartke, and D.E. Berryman -- Alzheimer's disease : genetics, pathogenesis, models, and experimental therapeutics / P.C. Wong ... [et al.] -- How does caloric restriction increase the longevity of mammals? / R. Weindruch .. [et al.] -- The determination of aging rate by coordinated resistance to multiple forms of stress / G.J. Lithgow and R.A. Miller -- Molecular mechanisms of aging : insights from budding yeast / S.-J. Lin and D. Sinclair -- Genetics of exceptional longevity / T.T. Perls and P. Sebastiani -- Mammalian metabolism in aging / P. Puigserver and C.R. Kahn -- Telomeres and telomerase in aging and cancer / J.W. Shay and W.E. Wright
    Pages: viii, 610 p.
    ISBN: 9780879698249
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    B110:138 departmental collection or stack – please contact the library
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  • 7
    Call number: QZ241:76
    Keywords: Tumor / Histologie
    Pages: XIV, 471 S., 314 ABB.
    ISBN: 3-540-09792-9
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    QZ241:76 available
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  • 8
    Keywords: Life sciences ; Human Genetics ; Psychiatry ; Systems Biology ; Life sciences ; Systems Biology ; Human Genetics ; Psychiatry ; Springer eBooks
    Description / Table of Contents: Consciousness, Crosstalk, and the Mereological Fallacy -- A Cognitive Paradigm for Gene Expression -- Western Atomism and its Culture-Bound Syndromes -- Environmental Induction of Neurodevelopmental Disorders -- Sleep, Psychopathology and Culture -- Embodied cognition and its disorders -- Tools for the Future: Hidden Symmetries -- Psychopathologies of automata I: autonomous vehicle systems -- Psychopathologies of automata II: autonomous weapons and centaur systems -- The dynamics of environmental insult -- Social psychopathology: military doctrine and the madness of crowds -- Mathematical Appendix -- Index
    Abstract: This book explores mental disorders from a uniquely evolutionary perspective. Although there have been many attempts to mathematically model neural processes and, to some extent, their dysfunction, there is very little literature that models mental function within a sociocultural, socioeconomic, and environmental context. Addressing this gap in the extant literature, this book explores essential aspects of mental disorders, recognizing the ubiquitous role played by the exaptation of crosstalk between cognitive modules at many different scales and levels of organization, the missing heritability of complex diseases, and cultural epigenetics. Further, it introduces readers to valuable control theory tools that permit the exploration of the environmental induction of neurodevelopmental disorders, as well as the study of the synergism between culture, psychopathology and sleep disorders, offering a distinctively unique resource
    Pages: XII, 236 p. 31 illus. : online resource.
    ISBN: 9783319539102
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  • 9
    Unknown
    New York : Raven Press
    Call number: 05-PHA-40:19(3)
    Keywords: Toxicology / methods
    Pages: xx, 1468 p. : ill.
    Edition: 3. ed.
    ISBN: 0-7817-0131-7
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    05-PHA-40:19(3) departmental collection or stack – please contact the library
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  • 10
    Keywords: Otorhinolaryngology ; Neurosciences ; Otorhinolaryngology ; Neurosciences ; Springer eBooks
    Description / Table of Contents: Preface -- Visual Influence on Auditory Perception -- Cue Combination Within a Bayesian Framework -- Toward a Model of Auditory-Visual Speech Intelligibility -- An Object-Based Interpretation of Audiovisual Processing -- Hearing in a “Moving” Visual World: Coordinate Transformations Along the Auditory Pathway -- Multisensory Processing in the Auditory Cortex -- Audiovisual Integration in the Primate Prefrontal Cortex -- Using Multisensory Integration to Understand the Human Auditory Cortex -- Combining Voice and Face Content in the Primate Temporal Lobe -- Neural Network Dynamics and Audiovisual Integration -- Cross-Modal Learning in the Auditory System -- Multisensory Processing Differences in Individuals with Autism Spectrum Disorder
    Abstract: Auditory behavior, perception, and cognition are all shaped by information from other sensory systems. This volume examines this multi-sensory view of auditory function at levels of analysis ranging from the single neuron to neuroimaging in human clinical populations. Visual Influence on Auditory Perception Adrian K.C. Lee and Mark T. Wallace Cue Combination within a Bayesian Framework David Alais and David Burr Toward a Model of Auditory-Visual Speech Intelligibility Ken W. Grant and Joshua G. W. Bernstein An Object-based Interpretation of Audiovisual Processing Adrian K.C. Lee, Ross K. Maddox, and Jennifer K. Bizley Hearing in a “Moving” Visual World: Coordinate Transformations Along the Auditory Pathway Shawn M. Willett, Jennifer M. Groh, Ross K. Maddox Multisensory Processing in the Auditory Cortex Andrew J. King, Amy Hammond-Kenny, Fernando R. Nodal Audiovisual Integration in the Primate Prefrontal Cortex Bethany Plakke and Lizabeth M. Romanski Using Multisensory Integration to Understand Human Auditory Cortex Michael S. Beauchamp Combining Voice and Face Content in the Primate Temporal Lobe Catherine Perrodin and Christopher I. Petkov Neural Network Dynamics and Audiovisual Integration Julian Keil and Daniel Senkowski Cross-Modal Learning in the Auditory System Patrick Bruns and Brigitte Röder Multisensory Processing Differences in Individuals with Autism Spectrum Disorder Sarah H. Baum Miller, Mark T. Wallace Adrian K.C. Lee is Associate Professor in the Department of Speech & Hearing Sciences and the Institute for Learning and Brain Sciences at the University of Washington, Seattle Mark T. Wallace is the Louise B McGavock Endowed Chair and Professor in the Departments of Hearing and Speech Sciences, Psychiatry, Psychology and Director of the Vanderbilt Brain Institute at Vanderbilt University, Nashville Allison B. Coffin is Associate Professor in the Department of Integrative Physiology and Neuroscience at Washington State University, Vancouver, WA Arthur N. Popper is Professor Emeritus and research professor in the Department of Biology at the University of Maryland, College Park Richard R. Fay is Distinguished Research Professor of Psychology at Loyola University, Chicago
    Pages: XVI, 272 p. 70 illus., 49 illus. in color. : online resource.
    ISBN: 9783030104610
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