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Immunopharmacology and Inflammation (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Immunology ; Pharmaceutical technology ; Biomedicine ; Pharmaceutical Sciences/Technology ; Immunology ; Springer eBooks
Description / Table of Contents: Part 1-The Molecular Mechanisms of Inflammation -- Mediators of Inflammation -- Innate Immunity in Inflammation -- Adaptive Immunity in Inflammation -- Histamine -- Neural Regulation of Inflammation: Inflammation and Neurotransmitters -- Part 2-Resolution of Inflammation -- The Proresolving Mediators -- Part 3-Immunopharmacology -- Regulation of Innate Immunity in Inflammation -- Biochemistry of Neutrophil Regulation -- Immune Mechanisms in Atherosclerosis and Potential for Immune Modulation Therapies -- IL-1 Receptor Families Regulation of Immunity and Disease -- Part 4-Classical Drugs to Treat Inflammatory and Autoimmune Diseases -- Glucocorticoids Molecular Mechanisms -- Glucocorticoids Immunity and Inflammation -- Strategies and Compounds to Circumvent Glucocorticoid Induced Side Effects -- Part 5-Innovative Drugs to Treat Inflammatory Autoimmune Diseases -- Innovative Drugs for Allergy
Abstract: A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research. It addresses an audience with basic knowledge in the inflammatory process, immune system, and pharmacology. Immunopharmacology and Inflammation meets the needs of graduate students, junior and senior researchers and is useful as a source of the most current information for those already working in these fields
Pages: VIII, 331 p. 42 illus., 41 illus. in color. : online resource.
ISBN: 9783319776583
Obesity, Fatty Liver and Liver Cancer (2018)
Singapore : Springer Singapore
Keywords: Medicine ; Cancer Research ; Molecular Biology ; Hepatology ; Biomedicine ; Molecular Medicine ; Cancer Research ; Hepatology ; Springer eBooks
Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Epidemiology and etiology of NAFLD and associated HCC -- Chapter 3. Pathogenesis of NASH: How metabolic complications of overnutrition favour lipotoxicity and pro-inflammatory fatty liver disease -- Chapter 4. Chemokines and Chemokine Receptors in the Development of NAFLD -- Chapter 5. NAFLD related-HCC: the relationship with metabolic disorders -- Chapter 6. Hepatocellular carcinoma in obesity: Finding a needle in the haystack? -- Chapter 7. Dysregulated epigenetic modifications in the pathogenesis of NAFLD-HCC -- Chapter 8. The Influence of Gut Microbial Metabolism on the Development and Progression of Non-alcoholic Fatty Liver Disease -- Chapter 9. Microbiota, obesity and NAFLD -- Chapter 10. Autophagy, NAFLD and NAFLD-related HCC -- Chapter 11. Animal models of non-alcoholic fatty liver diseases and its associated liver cancer -- Chapter 12. Current prevention and treatment options for NAFLD
Abstract: This volume covers a state-of-the-art illustration of recent discoveries concerning obesity-related fatty liver diseases and liver cancer. The contents are extensive and comprehensive. It brings important topics in the field all together under one umbrella, from epidemiology and etiology, molecular pathogenesis, cellular biology, epigenetics, immunology, microbiology, animal models to therapeutic approaches and treatments. All the book contributors are leading experts in the field. It will appeal to researchers, clinicians and graduate students in obesity, fatty liver diseases, GI/Liver cancer field. It may also yield benefits for pharmaceutical companies with regard to drug discovery
Pages: XII, 157 p. 24 illus., 23 illus. in color. : online resource.
ISBN: 9789811086847
The Heterogeneity of Cancer Metabolism (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Cancer Research ; Immunology ; Biomedicine ; Cancer Research ; Immunology ; Springer eBooks
Description / Table of Contents: Part 1: The metabolism of cancer cells -- Chapter 1: Glucose Metabolism -- Chapter 2: Glutamine Metabolism -- Chapter 3: Amino Acid Metabolism -- Chapter 4: Lipid Metabolism -- Chapter 5: Epigenetics and oncometabolites -- Part 2: Heterogeneity of Cancer Metabolism - Chapter 1: Specific oncogenetic mutations lead to specific metabolic phenotypes within the same tissue of origin -- Chapter 2: Intratumoral heterogeneity of cancer cell metabolism -- - Chapter 3: Differential metabolism in vitro and in vivo -- Part 3: Carcinoma associated fibroblasts -- Chapter 1: Characteristics of CAF's -- Chapter 2: Reverse Warbug EFF -- Chapter 3: Metabolic exchange between CAFs and cancer cells
Abstract: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies
Pages: XV, 183 p. 31 illus. in color. : online resource.
ISBN: 9783319777368
Keywords: Medicine ; Molecular Biology ; Cell Biology ; Biomedicine ; Molecular Medicine ; Cell Biology ; Springer eBooks
Description / Table of Contents: Chapter 1: Can the Single Cell Make Biomedicine Different (Wang) -- Chapter 2: Automated Single-cell Analysis and Isolation System (Tatematsu) -- Chapter 3: Single-cell non-coding RNA in Embryonic Development (Fu) -- Chapter 4: High Throughput Single Cell RNA sequencing, Bioinformatics Analysis and Applications (Huang) -- Chapter 5: Circulating Tumor Cells (Heymann) -- Chapter 6: Super-Resolution Fluorescence Microscopy for Single Cell Imaging (Feng) -- Chapter 7: Single Cell Proteomics for Molecular Targets in Lung Cancer (Wang) -- Chapter 8: Therapeutic Antibody Discovery in Infectious Diseases Using Single-Cell Analysis (Alexandria Voigt) -- Chapter 9: Single Cell Genetics and Epigenetics in Early Embryo (Wei) -- Chapter 10: The Potential Roles and Advantages of Single Cell Sequencing in The Diagnosis and Treatment of Hematological Malignancies (Shi) -- Chapter 11: Application of Single Cell Sequencing in Cancer (Yu) -- Chapter 12: Emergence of Bias During the Synthesis and Amplification of cDNA for scRNA-seq (Luo) -- Chapter 13: Detection and Application of RNA Editing in Cancer (Qian) -- Chapter 14: Is pooled CRISPR-screening the Dawn of a New Era for Functional Genomics (Yao) -- Chapter 15: Single Cell Sequencing in Respiratory Diseases (Zeng) -- Chapter 16: The Significance of Single-cell Analysis in Stem Cells (Zhuge)
Abstract: The book focuses on various detection targets applied in single cell studies, including tumor tissue cells, circulating tumor cells (CTCs), disseminated tumor cells (DTCs), circulating tumor DNA (ctDNA), cell-free DNA (cfDNA) and cancer stem cells (CSCs). It also discusses and compares detection methods using these detection targets in different fields to reveal single cell biomedical functions. The volume focuses not only on the methods already been established and validated, and also the methods newly developed. The book also highlights the importance and potential of single cell biomedicine in the development and validation of precision medicine strategies. It is useful for researchers and students in the field of cell biology, molecular medicine and precision medicine etc
Pages: VI, 195 p. 94 illus., 61 illus. in color. : online resource.
ISBN: 9789811305023
Drosophila Models for Human Diseases (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Human Genetics ; Neurosciences ; Pharmacology ; Metabolic Diseases ; Cell Biology ; Biomedicine ; Human Genetics ; Cell Biology ; Pharmacology/Toxicology ; Neurosciences ; Metabolic Diseases ; Springer eBooks
Abstract: Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases
Pages: X, 308 p. 79 illus., 64 illus. in color. : online resource.
ISBN: 9789811305290
Biostatistics for oncologists (2018)
New York : Demos Medical
Call number: W26.5:143
Keywords: Biostatistics ; Medical Oncology / methods
Description / Table of Contents: Why study biostatistics? -- Summarizing and graphing data -- Sampling -- Statistical estimation -- Hypothesis testing -- Correlation and regression-- Categorical data analysis -- Survival analysis methods -- Guide to choosing the appropriate statistical test -- Non-inferiority analysis -- Study designs -- Self-study multiple choice questions -- Self-study answers and rationales
Notes: Includes index.
Pages: xiv, 186 pages : illustrations
ISBN: 9780826168580
A beginner's guide to targeted cancer treatments (2018)
Hoboken, NJ. : Wiley
Call number: QZ267:522
Keywords: Neoplasms / drug therapy ; Molecular Targeted Therapy / methods
Description / Table of Contents: An introduction to cancer cell biology & genetics -- Introducing targeted cancer treatments -- Treatments that block proteins involved in cell communication -- Drugs that target : angiogenesis, fusion proteins, PARP, hedgehog signalling and CDKs -- Immunotherapy treatments -- Progress in developing targeted treatments for common solid cancers -- Targeted treatments for haematological cancer
ISBN: 9781119126799
Animal Biotechnology : 2 / Emerging Breeding Technologies (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Biomedical Engineering ; Genetic Engineering ; Animal genetics ; Biomedicine ; Biomedical Engineering/Biotechnology ; Veterinary Medicine/Veterinary Science ; Animal Genetics and Genomics ; Genetic Engineering ; Springer eBooks
Description / Table of Contents: 1. Somatic Cloning of Livestock by Somatic Cell Nuclear Transfer -- 2. Commercial Applications of SCNT in Livestock -- 3. Epigenetic Features of Animal Biotechnologies -- 4. Current Status of Genomic Maps, Genomic Selection/GBV in Livestock -- 5. Embryo Biopsies for Genomic Selection -- 6. Production of Transgenic Livestock: Overview of Transgenic Technologies -- 7. DNA-Nucleases and Their Use in Livestock Production -- 8. Regulatory Dysfunction Inhibits the Development and Application of Transgenic Livestock for use in Agriculture -- 9. Genetically Engineered Large Animals in Biomedicine -- 10. Stem Cells and Cell Conversion in Livestock -- 11. The Legal Governance of Animal Biotechnologies -- 12. Ethical Aspects of Animal Biotechnology -- 13. Public Perception of Animal Biotechnology
Abstract: This two-volume textbook provides a comprehensive overview on the broad field of Animal Biotechnology with a special focus on livestock reproduction and breeding. The reader will be introduced to a variety of state-of-the-art technologies and emerging genetic tools and their applications in animal production. Also, ethics and legal aspects of animal biotechnology will be discussed and new trends and developments in the field will be critically assessed. The two-volume work is a must-have for graduate students, advanced undergraduates and researchers in the field of veterinary medicine, genetics and animal biotechnology. This second volume is dedicated to genetic tools in animal biotechnology such as somatic cloning, transgenic technologies and the application of stem cells in livestock breeding. Also, ethics and legal aspects are discussed
Pages: VIII, 303 p. 46 illus., 40 illus. in color. : online resource.
ISBN: 9783319923482
Modeling Methods for Medical Systems Biology : Regulatory Dynamics Underlying the Emergence of Disease Processes (2018)
Cham : Springer International Publishing
Keywords: Life sciences ; Bioinformatics ; Systems Biology ; Microbial genetics ; Microbial genomics ; Mathematical models ; Life sciences ; Systems Biology ; Microbial Genetics and Genomics ; Mathematical Modeling and Industrial Mathematics ; Computational Biology/Bioinformatics ; Springer eBooks
Description / Table of Contents: Introduction -- Medical systems biology -- Modeling procedures -- Case of study -- Conclusions and Perspectives -- Bibliography
Abstract: This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach
Pages: XXI, 258 p. 60 illus. in color. : online resource.
ISBN: 9783319893549
RadCases musculoskeletal radiology (2018)
New York : Thieme
(RadCases, 5)  
Call number: WN200:75/5(2)
Keywords: Musculoskeletal Diseases / diagnostic imaging ; Radiography ; Musculoskeletal System / diagnostic imaging ; Diagnosis, Differential ; Diagnostic Imaging / methods
Notes: Preceded by Musculoskeletal radiology / edited by Glenn M. Garcia. 2010.
Pages: 257 pages : illustrations
Edition: 2nd edition.
ISBN: 9781626232440
Molecular Mechanisms of Autonomy in Biological Systems : Relativity of Code, Energy and Mass (2018)
Cham : Springer International Publishing
Keywords: Life sciences ; Cancer Research ; Systems Biology ; Stem Cells ; Regenerative Medicine ; Tissue Engineering ; Life sciences ; Stem Cells ; Regenerative Medicine/Tissue Engineering ; Systems Biology ; Cancer Research ; Springer eBooks
Description / Table of Contents: Relativity of Code, Energy, and Mass versus Relativi-ty of Energy and Mass -- Molecular Mechanism of Coding and Autonomous Decision Making in Biological Systems -- Molecular mechanism of self-organization in biologi-cal systems -- Molecular mechanism of self-fueling in biological systems by relativity of code, energy, and mass -- Relativity of code, energy, and mass: Molecular mechanisms of autonomy in biological systems -- Molecular mechanism of autonomy and self-organization: an emergent concept for the future of biomedical sciences -- Conclusion -- Index
Abstract: This book presents a novel molecular description for understanding the regulatory mechanisms behind the autonomy and self-organization in biological systems. Chapters focus on defining and explaining the regulatory molecular mechanisms behind different aspects of autonomy and self-organization in the sense of autonomous coding, data processing, structure (mass) formation and energy production in a biological system. Subsequent chapters discuss the cross-talk among mechanisms of energy, and mass and information, transformation in biological systems. Other chapters focus on applications regarding therapeutic approaches in regenerative medicine. Molecular Mechanisms of Autonomy in Biological Systems is an indispensable resource for scientists and researchers in regenerative medicine, stem cell biology, molecular biology, tissue engineering, developmental biology, biochemistry, biophysics, bioinformatics, as well as big data sciences, complexity and soft computing
Pages: XIII, 134 p. 93 illus., 86 illus. in color. : online resource.
ISBN: 9783319918242
Big data in medical image processing (2018)
Boca Raton, FL : CRC Press
Call number: WN180:7
Keywords: Image Processing, Computer-Assisted ; Data mining ; Diagnostic Imaging ; Decision Support Systems, Clinical
Notes: "A science publishers book."
Pages: vi, 202 p. : illustrations
ISBN: 9781138557246
Modern thoracic oncology (2018)
New Jersey : World Scientific
Call number: QZ365WF658:175/1 ; QZ365WF658:175/2 ; QZ365WF658:175/3
Keywords: Thoracic Neoplasms
Description / Table of Contents: Volume 1. Introduction -- Volume 2. Trachea, lung, and pleura -- Volume 3. Esophagus, mediastinum, chest wall, and diaphragm
ISBN: 9789814725514
Quality Management in Scientific Research : Challenging Irreproducibility of Scientific Results (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Life sciences ; Biomedicine ; Biomedicine general ; Life Sciences, general ; Springer eBooks
Description / Table of Contents: Part I: Principles, references and standards -- Quality basics -- Total Quality Management -- Quality certification and accreditation -- Quality Standards -- PART II: Quality and Basic Biomedical Research -- What is Basic Biomedical Research -- Conscious Management -- Quality along the Research project -- International references and models -- Quality management in basic biomedical research -- Part III: Methodologies and tools -- 7 basic tools of TQM -- Decision making -- Problem solving -- Teamworking -- Project Management -- Knowledge Management -- Failure Mode and Effect Analysis.-Design of experiment -- Lean Management and Six Sigma -- Conclusion.-Acknowledgements -- Bibliography -- References
Abstract: In recent years, the attention of the scientific and social community has not solely been on producing new findings, but increasingly also on the related issues of the reliability, safety, and efficacy of the discoveries made, as well as the efficient and effective use of resources. The adoption of management models and tools can help scientists to improve their research, ensuring valuable, robust and dependable outcomes. Quality disciplines have been widely used for decades in industrial and business fields, building a knowledge base that can be translated and exploited, much to the advantage of scientific research. However, quality references in scientific research are still extremely rare and largely limited to an international guideline and a few sector-specific standards. Despite WHO and EU Commission campaigns, there are still precious few practical texts that offer researchers guidance on quality principles and provide simple tools and methodologies for their daily work. The book, starting from the problem of the reproducibility of scientific results and the substantial contribution that the Quality approach can make to research (Chapter 1), introduces the reader to key principles and basic concepts of Quality and illustrates both general and research-specific quality standards, paving the way for further discussion (Chapter 2). In turn, Chapter 3 presents detailed applications of Quality principles in various aspects of research, from study and ethics to materials and equipment management. Chapters 4 and 5, respectively, are devoted to Quality tools and Quality methodologies, as well as soft skills, all of which are valuable to scientific experimentation and study management. The concepts and practical tools discussed are extensively illustrated with examples from actual applications in scientific research
Pages: XIV, 205 p. 74 illus., 64 illus. in color. : online resource.
ISBN: 9783319767505
Clinical Investigation (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Neurochemistry ; Respiratory organs / Diseases ; Neurobiology ; Medicine & Public Health ; Pneumology/Respiratory System ; Neurobiology ; Neurochemistry ; Springer eBooks
Description / Table of Contents: Prognostic Value of Osteoprotegerin and sRANKL in Bronchoalveolar Lavage Fluid of Patients with Advanced Non-Small Cell Lung Cancer, W. Naumnik, I. Płońska, M. Ossolińska, J. Nikliński, and B. Naumnik -- Melatonin and Metformin Diminish Oxidative Stress in Heart Tissue in a Rat Model of High Fat Diet and Mammary Carcinogenesis, N. Kurhaluk, B. Bojkova, M. Radkowski, O.V. Zaitseva, S. Kyriienko, U. Demkow, and P.J. Winklewski -- Evaluation of the Implementation of Hospital Antibiotic Policy in Oncosurgery Ward: a Six-Year Experience, A. Nitsch-Osuch, D. Okrucinski, M. Dawgialło, I. Gołębiak, and E. Kuchar -- Surgical Correction of Pectus Excavatum by the Nuss Procedure: a 15-Year Experience Study, P. Cierpikowski, A. Rzechonek, P. Błasiak, H. Lisowska, G. Pniewski, and P. Le Pivertl -- Influence of Inhaled Corticosteroids on Bronchial Inflammation and Pulmonary Function in Chronic Obstructive Pulmonary Disease with Moderate Obstruction, I. Toczyska, E. Zwolińska, and A. Chcialowski -- Association between Vitamin D and Carboxy-terminal Cross-Linked Telopeptide of Type I Collagen in Children during Growth Hormone Replacement Therapy, E. Witkowska-Sędek, A. Stelmaszczyk-Emmel, A. Kucharska, U. Demkow, and B. Pyrżak -- Weight Disorders in Short Children, P. Tomaszewski, A. Majcher, K. Milde, and R. Stupnicki -- Neutrophil Gelatinase-Associated Lipocalin: a Biomarker for Early Diagnosis of Urinary Tract Infections in Infants, G. Krzemień, M. Pańczyk-Tomaszewska, D. Adamczuk, I. Kotuła, U. Demkow, and A. Szmigielska -- A Two-Week Fecal Microbiota Transplantation Course in Pediatric Patients with Inflammatory Bowel Disease, K. Karolewska-Bochenek, P. Grzesiowski, A. Banaszkiewicz, A. Gawronska, M. Kotowska, M. Dziekiewicz, P. Albrecht, A. Radzikowski, and I. Lazowska-Przeorek -- Specialized Pain Clinics in Primary Care: Common Diagnoses, Referral Patterns and Clinical Outcomes – Novel Pain Management Model, Y. Fogelman, E. Carmeli, A. Minerbi, H. Baruch, and S. Vulfsons
Abstract: Clinical investigation plays an essential role in the differential diagnosis, biomarker development, and therapy and cure of diseases. The book presents a bench-to-bed approach, with broad empirical coverage by experienced practitioners. The articles include topics like cytokine receptors in lung cancer, conduciveness of oxidative stress to carcinogenesis, safety and effectiveness of surgical correction of deformed chest, diagnostic and treatment regimens in inflammation-ridden obstructive lung conditions, alterations in growth hormone secretion leading to disorders of growth and metabolism, microbiota transplantation in pediatric patients, and the promising markers of renal epithelial injury. Yet another issue concerns the restructuring of chronic pain management by establishing the community-based specialized pain clinics. The book aims to disseminate and deliberate on the latest interdisciplinary medical knowledge to enhance clinical outcomes. Being a blend of clinical investigation and practice the book is addressed to physicians, scientists, and allied health care professionals
Pages: VIII, 100 p. : online resource.
ISBN: 9783319740805
Deep learning with R (2018)
Shelter Island, N.Y. : Manning
Call number: QA402.5:9a ; QA402.5:9 ; C010:7
Keywords: R (Computer program language) ; Artificial intelligence ; Neural networks (Computer science) ; Machine learning / Technological innovations ; Mathematical statistics / Data processing ; Computer vision
Abstract: Introduces deep learning systems using the powerful Keras library and its R language interface. The book builds your understanding of deep learning through intuitive explanations and practical examples
Pages: xxi, 335 pages : illustrations, charts
ISBN: 9781617295546
Advances in Comparative Immunology (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Immunology ; Medical Microbiology ; Invertebrates ; Vertebrates ; Biomedicine ; Immunology ; Medical Microbiology ; Invertebrates ; Vertebrates ; Springer eBooks
Description / Table of Contents: Acknowledgements and Reminiscences -- Preface -- Part I. From Prokaryotes to Urochordates -- Introduction: Evolution of Immunity -- Allorecognition and Innate Immunity in the Dictyostelid Social Amoebae -- Cnidarian Immunity: Anthozoans in the Hot Seat -- Molecular Dissection of the Planarian Innate Immune System -- The C. elegans Model for Innate Immunity -- Earthworm Immunity: Quo Vadis? Advances and new Paradigms in the Omics Era -- Recognition of Non-Self in Earthworms -- Immunity in Mollusks: Recognition and Effector Mechanisms with a Focus on Bivalvia -- Molluscan immunobiology: Challenges in the Anthropocene Epoch -- The Complex Immune System in Echinoderms -- Natural Chimerism and Tolerance Induction in a Colonial Chordate -- The Inflammatory Response: The Basic Process of the Ascidians Innate Immunity -- Part II. From Cephalochordates to Vertebrates -- Complex Immunity in Cephalochordates -- The Origin and Early Evolution of Adaptive Immune Systems -- The Immune System of Cartilaginous Fishes -- Immune System of Teleosts -- Humoral Immunity in Reptiles -- Cellular Immunity in Reptiles -- The Immunological Characteristics of Fowls and Ostriches -- Immunology of Bats -- Elephant Immune System -- Comparative Phylogeny of the Nasopharynx-Associated Lymphoid Tissue -- Part III. Future Paths, Climate Change, Environmental Influences, Cancer, Therapy -- An Introduction to Ecoimmunology -- Environmental Interactions and Ecotoxicity in Relation to the Earthworm Immune System -- P53 Protein Family in Molluscan Transmissible Cancer: Lessons Learned -- Global Amphibian Declines Caused by an Emerging Infectious Disease and Inadequate Immune Responses -- Invertebrate Immunology from the Clinician’s Perspective -- Pathogens and Cancer: Clonal Processes and Evolution
Abstract: Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine
Pages: XL, 1048 p. 204 illus., 174 illus. in color. : online resource.
ISBN: 9783319767680
Bioinformatics and the Cell : Modern Computational Approaches in Genomics, Proteomics and Transcriptomics (2018)
Cham : Springer International Publishing
Keywords: Life sciences ; Proteomics ; Bioinformatics ; Cell Biology ; Evolutionary Biology ; Life sciences ; Bioinformatics ; Proteomics ; Cell Biology ; Evolutionary Biology ; Springer eBooks
Description / Table of Contents: Blast and Fasta -- Sequence alignment -- Contig assembly -- DNA replication and viral evolution -- Gene and motif prediction -- Hidden Markov Models -- Gibbs Sampler -- Bioinformatics and vertebrate mitochondria -- Characterizing translation efficiency -- Protein isoelectric point -- Bioinformatics and Two-Dimensional Protein Separation -- Self-Organizing Map and other clustering Algorithms -- Molecular Phylogenetics -- Fundamentals of Proteomics
Abstract: This second edition integrates the more technical and mathematical aspects of bioinformatics with concrete examples of their application to current research problems in molecular and cellular biology. This broad, unified approach is made possible, in large part, by the very wide scope of Dr. Xia’s own research experience. The integration of genomics, proteomics and transcriptomics into a single volume makes this book required reading for anyone entering the new and emerging field of Systems Biology
Pages: XIII, 489 p. 122 illus., 59 illus. in color. : online resource.
Edition: 2nd ed. 2018.
ISBN: 9783319906843
Wilson and Walker's principles and techniques of biochemistry and molecular biology (2018)
Cambridge : Cambridge University Press
Call number: QP519:90(8)
Keywords: Biochemistry ; Molecular Biology
Description / Table of Contents: Biochemical and molecular biological methods in life sciences studies -- Basic principles -- Cell culture techniques -- Recombinant DNA techniques and molecular cloning -- Preparative protein biochemistry -- Electrophoretic techniques -- Immunochemical techniques -- Flow cytometry -- Radioisotope techniques -- Principles of clinical biochemistry -- Microscopy -- Centrifugation and ultracentrifugation -- Spectroscopic techniques -- Basic techniques probing molecular structure and interactions -- Mass spectrometric techniques -- Fundamentals of bioinformatics -- Fundamentals of chemoinformatics -- The python programming language -- Data analysis -- Fundamentals of genome sequencing and annotation -- Fundamentals of proteomics -- Fundamentals of metabolomics -- Enzymes and receptors -- Drug discovery and development
Pages: xxx, 929 p. : ill.
Edition: 8th ed.
ISBN: 9781107162273
Oncology clinical trials : successful design, conduct, and analysis (2018)
New York, N.Y. : Demos Medical Publishing
Call number: W26.5:142(2)
Keywords: Neoplasms / drug therapy ; Clinical Trials as Topic
Pages: xxii, 542 p. : ill.
Edition: 2nd edition.
ISBN: 9780826168726
Animal Biotechnology : 1 / Reproductive Biotechnologies (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Biomedical Engineering ; Genetic Engineering ; Animal genetics ; Biomedicine ; Biomedical Engineering/Biotechnology ; Veterinary Medicine/Veterinary Science ; Animal Genetics and Genomics ; Genetic Engineering ; Springer eBooks
Description / Table of Contents: 1. Evolution of Animal Breeding and Animal Biotechnology -- 2. Future Agricultural Animals: The Need for Biotechnology -- 3. Artificial Insemination in Domestic and Wild Animal Species -- 4. Technique and Application of Sex Sorted Sperm in Domestic Farm Animals -- 5. ET-Technologies in Domestic Cattle -- 6. ET-Technology in Small Ruminants -- 7. ET-Technology in Domestic Pigs -- 8. ET-Technologies in Horses -- 9. Endoscopy in Cattle Reproduction -- 10. Transvaginal Ultrasound-Guided Oocyte Retrieval (OPU: Ovum Pick-Up) in Cows and Mares -- 11. Preservation of Gametes and Embryos -- 12. In vitro Production of Farm Animal Embryos
Abstract: This two-volume textbook provides a comprehensive overview on the broad field of Animal Biotechnology with a special focus on livestock reproduction and breeding. The reader will be introduced to a variety of state-of-the-art technologies and emerging genetic tools and their applications in animal production. Also, ethics and legal aspects of animal biotechnology will be discussed and new trends and developments in the field will be critically assessed. The two-volume work is a must-have for graduate students, advanced undergraduates and researchers in the field of veterinary medicine, genetics and animal biotechnology. This first volume mainly focuses on artificial insemination, embryo transfer technologies in diverse animal species and cryopreservation of oocytes and embryos
Pages: VII, 304 p. 43 illus., 40 illus. in color. : online resource.
ISBN: 9783319923277
The Neuroimaging of Brain Diseases : Structural and Functional Advances (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Neurosciences ; Radiology ; Neurology ; Biomedicine ; Neurosciences ; Imaging / Radiology ; Neurology ; Springer eBooks
Description / Table of Contents: Magnetic Resonance Imaging: Basic Principles and Applications -- Brief Overview of Functional Imaging Principles -- Clinical Utility of Resting State Functional MRI -- The Neuroimaging of Stroke: Structural and Functional Advances -- New Insights in Brain Tumors Magnetic Resonance Investigation -- Epilepsy Imaging -- In vivo Positron Emission Tomography of Extrastriatal Non-Dopaminergic Pathology in Parkinson Disease -- Structural and Functional Neuroimaging in Multiple Sclerosis: From Atrophy, Lesions to Global Network Disruption -- Neuroimaging in Ataxias -- Recent Insights from fMRI Studies Into the Neural Basis of Reciprocal Imitation in Autism Spectrum Disorders -- Functional Connectivity in Dementia -- MRI Neuroimaging and Psychiatry -- The Implications of Brain Plasticity and Task Selectivity for Visual Rehabilitation of Blind and Visually Impaired Individuals -- NeuroImaging of Pain
Abstract: Notable experts in the field of neuroimaging provide comprehensive overviews of advances in functional and structural aspects of both common and uncommon brain disorders. Functional imaging is evolving quickly but researchers and clinicians do not always have a strong understanding of the fundamental basis of the imaging techniques that they use. By focusing on both structure and function this book will provide a strong foundation for emerging developments in the field
Pages: XIV, 353 p. 68 illus., 46 illus. in color. : online resource.
ISBN: 9783319789262
Wissenschaftsmanagement : Handbuch & Kommentar (2017)
Bonn : Lemmens Medien
Call number: HD38:8
Keywords: Management
Pages: 912 p. : ill.
ISBN: 9783868560138
Nanomedicine : Gene Delivery, Imaging and Evaluation Systems (2018)
Cham : Springer International Publishing
Keywords: Medicine ; Gene Therapy ; Molecular Biology ; Biomedical Engineering ; Biomedicine ; Molecular Medicine ; Gene Therapy ; Biomedical Engineering/Biotechnology ; Springer eBooks
Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Non-Viral Gene Delivery -- Chapter 3. Specific Systems for Imaging -- Chapter 4. Specific Systems for Imaging -- Chapter 5. Conclusions and Perspective
Abstract: This book gives an overview of current nanomedical techniques and applications. It brings together information from various scientific fields, focusing particularly on gene delivery and imaging systems
Pages: V, 125 p. 39 illus., 28 illus. in color. : online resource.
ISBN: 9783319782591