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  • 1
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    New York : Springer
    Associated volumes
    Call number: QZ202.6:30(2)
    Keywords: AIDS malignancies ; Viral carcinogenesis ; Oncogenic Viruses ; Tumor Virus Infections ; Neoplasms / etiology ; Acquired Immunodeficiency Syndrome
    Pages: viii, 250 p. : ill. (some col.)
    Edition: 2nd ed.
    ISBN: 9783030035013
    Signatur Availability
    QZ202.6:30(2) available
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  • 2
    Keywords: Immunology ; Microbiology ; Medical virology ; Immunology ; Medical Microbiology ; Virology ; Springer eBooks
    Description / Table of Contents: Activity-based protein profiling – enabling multimodal functional studies of microbial communities -- Activity-Based Protein Profiling Methods to Study Bacteria: The Power of Small-Molecule Electrophiles -- Opportunities and Challenges in Activity-Based Protein Profiling of Mycobacteria -- Activity-Based Protein Profiling at the Host–Pathogen Interface -- Chemical Proteomic Profiling of Protein Fatty-Acylation in Microbial Pathogens -- How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling -- ABPP and Host–Virus Interactions -- Activity-Based Protein Profiling for the Study of Parasite Biology -- Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling -- Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics -- Development of Activity-Based Proteomic Probes for Protein Citrullination -- Recent Advances in Activity-Based Protein Profiling of Proteases -- Opportunities for Lipid-Based Probes in the Field of Immunology -- Activity-Based Protein Profiling of Non-ribosomal Peptide Synthetases -- Target Identification of Bioactive Covalently Acting Natural Products -- Applications of Reactive Cysteine Profiling
    Abstract: This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions
    Pages: X, 417 p. 115 illus., 70 illus. in color. : online resource.
    ISBN: 9783030111434
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  • 3
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    Singapore : Springer
    Call number: QH324:49
    Keywords: Bioinformatics ; Medicine ; Statistics ; Biomedicine general ; Statistics for Life Sciences, Medicine, Health Sciences
    Description / Table of Contents: Part 1. BIOINFORMATICS FOR LIFE AND PERSONAL GENOME INTERPRETATION -- Chapter 1. Bioinformatics For Life -- Chapter 2. Next Generation Sequencing and Personal Genome Data Analysis -- Chapter 3. Personal Genome Data Analysis -- Chapter 4. Personal Genome Interpretation and Disease Risk Prediction -- Part 2. ADVANCED MICROARRAY DATA ANALYSIS -- Chapter 5. Advanced Microarray Data Analysis -- Chapter 6. Gene Expression Data Analysis -- Chapter 7. Gene Ontology and Biological Pathway-based Analysis -- Chapter 8. Gene-set Approaches and Prognostic Subgroup Prediction -- Chapter 9. MicroRNA Data Analysis -- Part 3. NETWORK BIOLOGY, SEQUENCE, PATHWAY AND ONTOLOGY INFORMATICS -- Chapter 10. Network Biology, Sequence, Pathway and Ontology Informatics -- Chapter 11. Motif and Regulatory Sequence Analysis -- Chapter 12. Molecular Pathways and Gene Ontology -- Chapter 13. Biological Network Analysis -- Part 4. SNPS, GWAS AND CNVS, INFORMATICS FOR GENOME VARIANTS -- Chapter 14. SNPs, GWAS, CNVs: Informatics for Human Genome Variations -- Chapter 15. SNP Data Analysis -- Chapter 16. GWAS Data Analysis -- Chapter 17. CNV Data Analysis -- Part 5. METAGENOME AND EPIGENOME, BASIC DATA ANALYSIS -- Chapter 18. Metagenome and Epigenome Data Analysis -- Chapter 19. Metagenome Data Analysis -- Chapter 20. Epigenome Databases and Tools -- Chapter 21. Epigenome Data Analysis -- Appendix A. BASIC PRACTICE USING R FOR DATA ANALYSIS -- Appendix B. APPLICATION PROGRAM FOR GENOME DATA ANALYSIS INSTALL GUIDE
    Abstract: This textbook describes recent advances in genomics and bioinformatics and provides numerous examples of genome data analysis that illustrate its relevance to real world problems and will improve the reader’s bioinformatics skills. Basic data preprocessing with normalization and filtering, primary pattern analysis, and machine learning algorithms using R and Python are demonstrated for gene-expression microarrays, genotyping microarrays, next-generation sequencing data, epigenomic data, and biological network and semantic analyses. In addition, detailed attention is devoted to integrative genomic data analysis, including multivariate data projection, gene-metabolic pathway mapping, automated biomolecular annotation, text mining of factual and literature databases, and integrated management of biomolecular databases. This textbook is primarily intended for life scientists, medical scientists, statisticians, data processing researchers, engineers, and other beginners in bioinformatics who are experiencing difficulty in approaching the field. However, it will also serve as a simple guideline for experts unfamiliar with the new, developing subfield of genomic analysis within bioinformatics
    Pages: xvi, 367 p. : ill.
    ISBN: 9789811319419
    Signatur Availability
    QH324:49 available
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  • 4
    Keywords: Microbiology ; Biomedical Engineering ; Microbial ecology ; Microbiology ; Biomedical Engineering/Biotechnology ; Microbial ecology ; Applied Microbiology ; Regenerative Medicine/Tissue Engineering ; Springer eBooks
    Description / Table of Contents: Chapter 1. The Dawn of Novel Biotechnological Applications of Polyhydroxyalkanoates -- Chapter 2. Strategy for biosynthesis of polyhydroxyalkonates polymers/copolymers and their application in drug delivery -- Chapter 3. Applications of Polyhydroxyalkanoates and its metabolites as transporters for bioactive molecules -- Chapter 4. Polyhydroxyalkanoates applications in antimicrobial agents' delivery and wound healing -- Chapter 5. Polyhydroxyalkanoates applications in Drug Carriers -- Chapter 6. Applications of polyhydroxyalkanoate based nanovehicles -- Chapter 7. Memory enhancers -- Chapter 8. Novel Biocontrol Agents: Short Chain Fatty Acids And More Recently, Polyhydroxyalkanoates -- Chapter 9. Potential Therapeutic Applications of Polyhydroalkanoates and Their Composites as Anti-microbial Agents -- Chapter 10. Polyhydroxyalkanoates (PHA) – Applications in Wound Treatment and as Precursors for Oral Drugs -- Chapter 11. Exploiting Polyhydroxyalkanoates for Tissue Engineering -- Chapter 12. CH4-based polyhydroxyalkanoate production: a step further towards a sustainable bioeconomy -- Chapter 13. Applications of PHA in Agriculture -- Chapter 14. Polyhydroxyalkanoates in Packaging -- Chapter 15. Approaches for Enhancing Extraction of bacterial polyhydroxyalkanoates for Industrial Applications -- Chapter 16. Nanofibers from polyhydroxyalkanoates and their applications in tissue engineering
    Abstract: This book presents the latest research on the uses of polyhydroxyalkanoates (PHA), introducing readers to these natural, biodegradable polyesters produced by microorganisms, their functions and applications. The individual chapters discuss the various potentials of these bioplastics, which offer an attractive alternative to non-biodegradable plastics. The book also describes the diverse medical and biomedical applications of PHAs, including their use as drug carriers, memory enhancers, and biocontrol agents, and examines their role in creating a more sustainable economy – which is the need of the hour
    Pages: XII, 420 p. 42 illus., 34 illus. in color. : online resource.
    ISBN: 9789811337598
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  • 5
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    Heidelberg : Springer
    Call number: QH442:222 ; ERW
    Keywords: Genetic Techniques
    ISBN: 9783642346934
    Signatur Availability
    QH442:222 available
    ERW in acquisition
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