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  • Biochemistry  (6)
  • Microbiology  (3)
  • Biomedical Research
  • DKFZ-publications
  • 1
    Call number: QC21:14(4)
    Keywords: Physics ; Chemistry ; Biochemistry
    Pages: xvii, 516 p. : ill.
    Edition: 4.,aktualisierte Aufl.
    ISBN: 9783662582497
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    QC21:14(4) available
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  • 2
    Call number: QP514:70(3)
    Keywords: Biochemistry
    Notes: Transl. of: Fundamentals of biochemistry, 5th edition, 2016.
    Pages: xxviii, 1463 p. : ill.
    Edition: 3., vollst. überarb. u. erw. Aufl.
    ISBN: 9783527342860
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    QP514:70(3) available
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  • 3
    Keywords: Immunology ; Microbiology ; Medical virology ; Immunology ; Medical Microbiology ; Virology ; Springer eBooks
    Description / Table of Contents: Activity-based protein profiling – enabling multimodal functional studies of microbial communities -- Activity-Based Protein Profiling Methods to Study Bacteria: The Power of Small-Molecule Electrophiles -- Opportunities and Challenges in Activity-Based Protein Profiling of Mycobacteria -- Activity-Based Protein Profiling at the Host–Pathogen Interface -- Chemical Proteomic Profiling of Protein Fatty-Acylation in Microbial Pathogens -- How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling -- ABPP and Host–Virus Interactions -- Activity-Based Protein Profiling for the Study of Parasite Biology -- Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling -- Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics -- Development of Activity-Based Proteomic Probes for Protein Citrullination -- Recent Advances in Activity-Based Protein Profiling of Proteases -- Opportunities for Lipid-Based Probes in the Field of Immunology -- Activity-Based Protein Profiling of Non-ribosomal Peptide Synthetases -- Target Identification of Bioactive Covalently Acting Natural Products -- Applications of Reactive Cysteine Profiling
    Abstract: This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions
    Pages: X, 417 p. 115 illus., 70 illus. in color. : online resource.
    ISBN: 9783030111434
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  • 4
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    Stuttgart : Thieme
    Call number: QR46:18(7)
    Keywords: Microbiology
    Notes: For online access to this volume please contact the library staff in room D124 (phone 3661, e-mail: http://www.dkfz.de/de/zbib/mitarbeiter/kontakt/fernleihe.php)
    Pages: xx, 718 p.
    Edition: 7., vollst. überarb. u. erw. Aufl.
    ISBN: 9783132423558
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    QR46:18(7) available
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  • 5
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    Cham : Springer
    Keywords: Human Genetics ; Biochemistry ; Biological models ; Human Genetics ; Protein Science ; Systems Biology ; Springer eBooks
    Description / Table of Contents: Preface -- Chromatin regulation by long non-coding RNAs -- Regulation of Eukaryotic Cell Differentiation by Long Noncoding RNAs -- Roles of long non-coding RNAs in X-chromosome inactivation -- Roles of Long Non-Coding RNAs in Genomic Imprinting -- Dysregulation of long noncoding RNAs in human disease -- Functions of long non-coding RNAs in non-mammalian systems -- Emerging technologies to study long non-coding RNAs -- Long non coding RNAs and nuclear body formation and function -- The role of long non-coding RNAs in immunity -- Novel methods to study long non-coding RNAs -- OMICs of long non-coding RNAs -- Cancer epigenetics and long non-coding RNAs -- Roles of long non-coding RNAs in human development -- Index
    Abstract: This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them
    Pages: VII, 187 p. 10 illus., 9 illus. in color. : online resource.
    Edition: 2nd ed. 2019.
    ISBN: 9783030170868
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  • 6
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    Hoboken, N.J. : Wiley
    Call number: QP514:72(5)
    Keywords: Biochemistry
    Notes: Previous ed.: 2013.
    Pages: various pagings : ill.
    Edition: 5th ed., global edition
    ISBN: 9781119451662
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    QP514:72(5) available
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  • 7
    Call number: W160:26(2)
    Keywords: DKFZ-publications ; Signal Transduction / physiology ; Intracellular Signaling Peptides and Proteins / physiology
    Pages: xiii, 639 p. : ill.
    Edition: 2nd edition.
    ISBN: 9780815342151
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    W160:26(2) available
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  • 8
    Keywords: Biochemistry ; Microbiology ; Biochemistry, general ; Microbiology ; Biological and Medical Physics, Biophysics ; Springer Nature Living Reference
    Abstract: Handbook of Molecular Life Sciences will focus on understanding biological phenomena at the level of molecules and their interactions that govern life processes. Volumes 1 to 3 will focus on genes and genomes, volumes 4 to 6 on protein structure and function, volumes 7 & 8 will explore systems biology, using genomics and proteomics as the focus and volumes 9 and 10 on molecular aspects of cell structure and function. Volume 11 will explore unifying concepts and theory from biology, chemistry, mathematics and physics that are essential for understanding the molecular life sciences and will also include sections on teaching perspectives and assessment tools. Volume 12 will cover basic aspects of the various experimental approaches that are used in the Molecular Life Sciences
    Pages: 10000 p. 1000 illus. in color. : online resource.
    ISBN: 9781461464365
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  • 9
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    Berlint : Springer
    Keywords: Biochemistry ; Microscopy ; Bioinformatics ; Engineering ; Biochemistry, general ; Biological and Medical Physics, Biophysics ; Protein Science ; Biological Microscopy ; Bioinformatics ; Nanotechnology and Microengineering ; Springer Nature Living Reference
    Description / Table of Contents: Proteins -- DNA and RNA -- Carbohydrates -- Macromolecular complexes, Mechanoenzymes -- Membrane biophysics -- Electron transfer -- Ion Channels -- Receptors -- Transporters -- Biomaterials & Biosensors -- Diffraction methods -- NMR -- EPR -- Optical spectroscopy -- X-ray spectroscopy -- Single molecule methods -- Computational Biophysics -- Thermodynamics -- Kinetics -- Mass spectrometry -- Molecular shape & hydrodynamics -- Electron microscopy -- Live cell & in vivo imaging -- Cell biophysics
    Abstract: The Encyclopedia of Biophysics is envisioned both as an easily accessible source of information and as a route into the scientific literature. It consists of two parts, Systems and Techniques. In the Techniques sections, each of the wide range of methods which fall under the heading of Biophysics are explained in detail, together with the value and the limitations of the information each provides. Techniques covered range from diffraction (X-ray, electron and neutron), through a wide range of spectroscopic methods (X-ray, optical, EPR, NMR) to imaging (from electron microscopy to live cell imaging and MRI), as well as computational and simulation approaches. In the Systems sections, biophysical approaches to particular biological systems or problems – from protein and nucleic acid structure to membranes, ion channels and receptors – are described. These sections, which have an emphasis on the integration of the different techniques, therefore provide an entry into Biophysics from the biological more than from the technique-oriented physical/chemical direction. Thus the Encyclopedia is intended to provide a resource both for biophysicists interested in approaches outside their immediate sub-discipline and for people coming to biophysics from either the physical or biological direction. Each of the sections will include concise introductions to the major concepts and methods, and outlines of more specific topics, in each case with links to a limited number of carefully selected key reviews and/or papers in the scientific literature. There will also be short definitions explaining key terms. Extensive cross-referencing (hyperlinks in the online version) between different articles will allow access to related topics in a user-friendly manner and time-efficient manner, including hyperlinks to key articles in the scientific literature
    Pages: CDXXV, 2807 p. : online resource.
    ISBN: 9783642359439
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