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  • Biomedical Engineering and Bioengineering  (6)
  • 1
    Keywords: Mass spectrometry ; Proteomics ; Biomedical Engineering ; Mass spectrometry ; Proteomics ; Biomedical Engineering/Biotechnology ; Biomedical Engineering and Bioengineering ; Springer eBooks
    Description / Table of Contents: Mass Spectrometry for Proteomics-based Investigation -- MALDI profiling and applications in medicine -- Applications of Matrix-Assisted Laser Desorption Ionization In-Source Decay Mass Spectrometry -- Proteome imaging: from classic to modern mass spectrometry-based molecular histology -- Mass Spectrometry-Based Tissue Imaging of Small Molecules -- Sequencing Proteins from Bottom to Top: Combining Techniques for Full Sequence Analysis of Glucokinase -- Proteomics and non-proteomics approaches to study stable and transient protein-protein interactions -- Contribution of Mass spectrometry-based Proteomics to Discoveries in Developmental Biology -- Profiling optimal conditions for capturing EDEM proteins complexes in melanoma using mass spectrometry -- The Methods employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein–Protein Interactions (PPIs) -- Identification of post-translational modifications (PTMs) of proteins by mass spectrometry -- Sequence Variant and Post-translational Modification Analysis During Cell Line Selection via High-throughput Peptide Mapping -- Selective derivatization of hexahistidine-tagged recombinant proteins -- Investigation of Antibody-Drug Conjugates by Mass Spectrometry -- Mass Spectrometry- and Computational Structural Biology-Based Investigation of Proteins and Peptides -- Strategies for Membrane Protein Analysis by Mass Spectrometry -- The Potential for Ion Mobility in Pharmaceutical and Clinical Analyses -- Application of Ion Mobility Mass Spectrometry in Lipidomics -- Mass Spectrometry in Advancement of Redox Precision Medicine -- Applications for mass spectrometry in the study of ion channel structure and function -- Immuno – affinity Mass Spectrometry: A Novel Approaches with Biomedical Relevance -- Developing well-annotated species-specific protein databases using comparative proteogenomics -- Stoichiometry of heavy metal binding to peptides involved in Alzheimer’s disease: mass spectrometric evidence -- Role of mass spectrometry in investigating a novel protein: the example of Tumor Differentiation Factor (TDF) -- Mass Spectrometry-Based Biomarkers in Drug Developmen -- Combinatorial Electrophoresis and Mass Spectrometry-Based Proteomics in Breast Milk for Breast Cancer Biomarker Discovery -- Proteomic approaches to dissect neuronal signalling pathways -- Mass Spectrometry for the Study of Autism and Neurodevelopmental Disorders -- Simplifying the proteome: Analytical strategies for improving peak capacity -- Exploration of nicotine metabolism in Paenarthrobacter nicotinovorans pAO1 by microbial proteomics -- Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) for Quantitative Proteomics -- Mass spectrometry based comparative proteomics using one dimensional and two dimensional SDS-PAGE of rat atria induced with obstructive sleep apnea -- 2D SDS PAGE in combination with western blotting and mass spectrometry is a robust method for protein analysis with many applications -- Pulse SILAC approaches to the measurement of cellular dynamics -- Protein Biomarkers in Major Depressive Disorder: an Update -- A Pilot Exploratory Proteomics Investigation of Mental Fatigue and Mental Energy -- Metabolomics and biomarker discovery -- Analytical Methods for Mass Spectrometry-Based Metabolomics Studies -- Trends in analysis of cortisol and its derivatives -- Detection of biomedically relevant stilbenes from wines by mass spectrometry -- Mass spectrometry as a complementary approach for noncovalently bound complexes based on cyclodextrins -- Trends in glycolipid biomarker discovery in neurodegenerative disorders by mass spectrometry -- Non-targeted Screening in Environmental Monitoring Programs -- Mass Spectrometric DNA Adduct Quantification by Multiple Reaction Monitoring and its Future Use for the Molecular Epidemiology of Cancer -- Bottlenecks in proteomics: an update -- Recent Applications of Mass Spectrometry at Clarkson University -- Index
    Abstract: This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field
    Pages: XXI, 813 p. 362 illus., 310 illus. in color. : online resource.
    Edition: 2nd ed. 2019.
    ISBN: 9783030159504
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  • 2
    Keywords: Biomedical Engineering ; Nanotechnology ; Oncology ; Biomedical Engineering/Biotechnology ; Nanotechnology ; Biomedical Engineering and Bioengineering ; Cancer Research ; Springer eBooks
    Description / Table of Contents: Unifying Next-Generation Biomarkers and Nanodiagnostic Platforms for Precision Prostate Cancer (PCa) Management -- Colorimetric Gene Fusion Diagnostics for Visual Binary Readout -- Label –Free Surface-Enhanced Raman Scattering Detection System for Clinical Biomarker Targets -- Amplification-Free Electrochemical RNA Biomarker Sensing -- Simultaneous Analysis of Multiple Biomarkers via High-Throughput Parallel Profiling
    Abstract: This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development
    Pages: XIII, 102 p. : online resource.
    Edition: 1st ed. 2019.
    ISBN: 9783030310004
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  • 3
    Keywords: Biomedical Engineering ; Signal processing ; Image processing ; Speech processing systems ; Radiology ; Biomedical Engineering/Biotechnology ; Biomedical Engineering and Bioengineering ; Signal, Image and Speech Processing ; Imaging / Radiology ; Springer eBooks
    Description / Table of Contents: What is Medical Imaging? -- Part I: From Signals… -- Basic Concepts -- Transmission: X-Rays -- Reflection : Ultrasound -- Emission: SPECT/PET -- Resonance: NMR -- Part II: …To Images -- A Revision of Frequency Analysis -- Basic Concepts -- Timing-Based Reconstruction -- Back-Projection Reconstruction: X-Ray and PET/SPECT -- Fourier Reconstruction: MRI -- Part III: Functional and Physiological Imaging -- Contrast Agents -- Tracer Kinetics -- Examples of Tracer Kinetic Methods -- Other Physiological and Functional MRI Methods
    Abstract: This introduction to medical imaging introduces all of the major medical imaging techniques in wide use in both medical practice and medical research, including Computed Tomography, Ultrasound, Positron Emission Tomography, Single Photon Emission Tomography and Magnetic Resonance Imaging. Principles of Medical Imaging for Engineers introduces fundamental concepts related to why we image and what we are seeking to achieve to get good images, such as the meaning of ‘contrast’ in the context of medical imaging. This introductory text separates the principles by which ‘signals’ are generated and the subsequent ‘reconstruction’ processes, to help illustrate that these are separate concepts and also highlight areas in which apparently different medical imaging methods share common theoretical principles. Exercises are provided in every chapter, so the student reader can test their knowledge and check against worked solutions and examples. The text considers firstly the underlying physical principles by which information about tissues within the body can be extracted in the form of signals, considering the major principles used: transmission, reflection, emission and resonance. Then, it goes on to explain how these signals can be converted into images, i.e., full 3D volumes, where appropriate showing how common methods of ‘reconstruction’ are shared by some imaging methods despite relying on different physics to generate the ‘signals’. Finally, it examines how medical imaging can be used to generate more than just pictures, but genuine quantitative measurements, and increasingly measurements of physiological processes, at every point within the 3D volume by methods such as the use of tracers and advanced dynamic acquisitions. Principles of Medical Imaging for Engineers will be of use to engineering and physical science students and graduate students with an interest in biomedical engineering, and to their lecturers
    Pages: XIV, 169 p. : online resource.
    Edition: 1st ed. 2019.
    ISBN: 9783030305116
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  • 4
    Keywords: Biomedical Engineering ; Computer vision ; Computer Simulation ; Radiology, Medical ; Computer science ; Biomedical Engineering/Biotechnology ; Biomedical Engineering and Bioengineering ; Computer Imaging, Vision, Pattern Recognition and Graphics ; Simulation and Modeling ; Imaging / Radiology ; Computational Science and Engineering ; Springer eBooks
    Description / Table of Contents: Chapter 1. The impact of patches on blood flow disorders in carotid artery -- Chapter 2. Numerical study of carotid bifurcation angle effect on blood flow disorders -- Chapter 3. Evaluating the effect of tissue anisotropy on brain tumor growth using a mechanically-coupled reaction-diffusion model -- Chapter 4. Prediction of stress and strain patterns from load rearrangement in human osteoarthritic femur head: finite element study with the integration of muscular forces and friction contact -- Chapter 5. Numerical simulation of the deployment process of a new stent produced by ultrasonic-microcasting: the role of the balloon’s constitutive modeling -- Chapter 6. New techniques for combined FEM-multibody anatomical simulation -- Chapter 7. Computational cell-based modelling and visualization of cancer development and progression -- Chapter 8. Estimation of 6 degree of freedom accelerations from head impact telemetry system outputs for computational modeling -- Chapter 9. Physiological Cybernetics: methods and applications -- Chapter 10. New computational solution to compute the uptake index from 99mTc-MDP bone scintigraphy images
    Abstract: This book gathers selected, extended and revised contributions to the 15th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE2018), and the 3rd Conference on Imaging and Visualization, which took place on 26-29 March, 2018, in Lisbon, Portugal. The respective chapters highlight cutting-edge methods, e.g. new algorithms, image analysis techniques, and multibody modeling methods; and new findings obtained by applying them in biological and/or medical contexts. Original numerical studies, Monte Carlo simulations, FEM analyses and reaction-diffusion models are described in detail, together with intriguing new applications. The book offers a timely source of information for biologists, engineers, applied mathematicians and clinical researchers working on multidisciplinary projects, and is also intended to foster closer collaboration between these groups
    Pages: X, 160 p. 98 illus., 88 illus. in color. : online resource.
    Edition: 1st ed. 2019.
    ISBN: 9783030230739
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  • 5
    Keywords: Biomedical Engineering ; Biomaterials ; Biomedical Engineering/Biotechnology ; Biomaterials ; Biomedical Engineering and Bioengineering ; Springer eBooks
    Description / Table of Contents: Chapter 1 - 3D Bioprinting Technologies -- Chapter 2 - Materials as Bioinks and Bioink Design -- Chapter 3 - Potential Clinical Applications of Three-Dimensional Bioprinting -- Chapter 4 - Bioprinting Vasculature -- Chapter 5 - 3D bioprinting in clinical cardiovascular medicine -- Chapter 6 - Understanding Cancer Cell Behavior Through 3D Printed Bone Microenvironments -- Chapter 7 - Three-Dimensional Bioprinting: Safety, Ethical and Regulatory Considerations -- Index
    Abstract: This book provides current and emerging developments in bioprinting with respect to bioprinting technologies, bioinks, applications, and regulatory pathways. Topics covered include 3D bioprinting technologies, materials such as bioinks and bioink design, applications of bioprinting complex tissues, tissue and disease models, vasculature, and musculoskeletal tissue. The final chapter is devoted to clinical applications of bioprinting, including the safety, ethical, and regulatory aspects. This book serves as a go-to reference on bioprinting and is ideal for students, researchers and professionals, including those in academia, government, the medical industry, and healthcare
    Pages: XIII, 209 p. 38 illus. in color. : online resource.
    Edition: 1st ed. 2019.
    ISBN: 9783030239060
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  • 6
    Keywords: Biomedical Engineering ; Computer vision ; Biomedical Engineering/Biotechnology ; Biomedical Engineering and Bioengineering ; Image Processing and Computer Vision ; Signal, Image and Speech Processing ; Springer eBooks
    Description / Table of Contents: Colonic Polyp Identification Using Pareto Depth Anomaly Detection Algorithm -- Comparative Study of Dermoscopic Hair Removal Methods -- Lower Limb Joint Angle Coordination Assessment at Sagittal Plane on Human Vertical Countermovement -- Biometric Identification Based on Forearm Vein Pattern -- Cross Recurrence Quantitative Analysis of Functional Magnetic Resonance Imaging -- Automatic Segmentation and Delineation of Intervertebral Discs on Lumbar Spine MR Images -- A Hybrid Approach For Breast Mass Categorization -- Skin Disease Diagnosis from Photographs Using Deep Learning -- Prediction of the Child’s Head Growth in the First Year of Life -- Influence of Mutual Rotation of Polarizing Filters on Light Intensity Measured With Collagen Fibres -- Automatic Extraction of Marbling Measures Using Image Analysis, for Evaluation of Beef Quality -- Layer Thickness Evaluation Between Medical Imaging and Additive Manufacturing
    Abstract: This book gathers full papers presented at the VipIMAGE 2019—VII ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing—held on October 16-18, 2019, in Porto, Portugal. It discusses cutting-edge methods, findings, and applications related to 3D vision, bio- and medical imaging, computer-aided diagnosis, image enhancement, image processing and analysis, virtual reality, and also describes in detail advanced image analysis techniques, such as image segmentation and feature selection, as well as statistical and geometrical modeling. The book provides both researchers and professionals with extensive and timely insights into advanced imaging techniques for various application purposes
    Pages: XXII, 706 p. 390 illus., 290 illus. in color. : online resource.
    Edition: 1st ed. 2019.
    ISBN: 9783030320409
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