Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

New Acquisitions Shelf

Export
Filter
  • Books  (7)
  • Pharmacology/Toxicology  (4)
  • Biomedical Research
  • Microbiology
  • DKFZ-publications
  • 1
    Keywords: Immunology ; Microbiology ; Medical virology ; Immunology ; Medical Microbiology ; Virology ; Springer eBooks
    Description / Table of Contents: Activity-based protein profiling – enabling multimodal functional studies of microbial communities -- Activity-Based Protein Profiling Methods to Study Bacteria: The Power of Small-Molecule Electrophiles -- Opportunities and Challenges in Activity-Based Protein Profiling of Mycobacteria -- Activity-Based Protein Profiling at the Host–Pathogen Interface -- Chemical Proteomic Profiling of Protein Fatty-Acylation in Microbial Pathogens -- How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling -- ABPP and Host–Virus Interactions -- Activity-Based Protein Profiling for the Study of Parasite Biology -- Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling -- Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics -- Development of Activity-Based Proteomic Probes for Protein Citrullination -- Recent Advances in Activity-Based Protein Profiling of Proteases -- Opportunities for Lipid-Based Probes in the Field of Immunology -- Activity-Based Protein Profiling of Non-ribosomal Peptide Synthetases -- Target Identification of Bioactive Covalently Acting Natural Products -- Applications of Reactive Cysteine Profiling
    Abstract: This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions
    Pages: X, 417 p. 115 illus., 70 illus. in color. : online resource.
    ISBN: 9783030111434
    Signatur Availability
    BibTip Others were also interested in ...
  • 2
    Keywords: Oncology ; Oncology   ; Toxicology ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer Nature Living Reference
    Abstract: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists
    Pages: 800 p. 50 illus. : online resource.
    ISBN: 9789400777446
    Signatur Availability
    BibTip Others were also interested in ...
  • 3
    Keywords: Oncology ; Toxicology ; Bioorganic chemistry ; Nanotechnology ; Cancer Research ; Pharmacology/Toxicology ; Bioorganic chemistry ; Nanotechnology ; Springer eBooks
    Description / Table of Contents: Chapter 1. General introduction and sources of flavonoids -- Chapter 2. Analytical techniques for the identification and quantification of Flavonoids -- Chapter 3. Chemistry and Synthetic overview of flavonoids -- Chapter 4. Metal complexation and chemopreventive patent studies of flavonoid -- Chapter 5. Molecular targets of flavonoids in cancer: recent advances -- Chapter 6. Absorption and Metabolism of flavonoids -- Chapter 7. Recent trend in flavonoids studies in term of health prospective -- Chapter 8. Role of nanotechnology in flavonoid mediated anti-cancer therapy -- Chapter 9. Clinical trial of Flavonoids in cancer
    Abstract: The book comprehensively introduces readers to various aspects of flavonoids, a category of natural metabolites that exhibits various pharmacological effects. It discusses their chemistry, absorption and metabolism, mechanisms of action and toxicology as well as future perspectives for clinical applications, and also provides detailed insights into their anti-cancer properties, since flavonoids are known to modulate tumor-associated intracellular as well as extracellular signaling pathways. The book also highlights the current research on the health effects of selected flavonoids, and their various roles in cancer prevention and treatment. Lastly, the book elucidates nanotechnology-mediated tools to enhance the bioavailability and solubility of flavonoids to improve their bioactivity and pharmacokinetic parameters
    Pages: XVIII, 181 p. 92 illus., 26 illus. in color. : online resource.
    ISBN: 9789811358746
    Signatur Availability
    BibTip Others were also interested in ...
  • 4
    Keywords: Biochemistry ; Microbiology ; Biochemistry, general ; Microbiology ; Biological and Medical Physics, Biophysics ; Springer Nature Living Reference
    Abstract: Handbook of Molecular Life Sciences will focus on understanding biological phenomena at the level of molecules and their interactions that govern life processes. Volumes 1 to 3 will focus on genes and genomes, volumes 4 to 6 on protein structure and function, volumes 7 & 8 will explore systems biology, using genomics and proteomics as the focus and volumes 9 and 10 on molecular aspects of cell structure and function. Volume 11 will explore unifying concepts and theory from biology, chemistry, mathematics and physics that are essential for understanding the molecular life sciences and will also include sections on teaching perspectives and assessment tools. Volume 12 will cover basic aspects of the various experimental approaches that are used in the Molecular Life Sciences
    Pages: 10000 p. 1000 illus. in color. : online resource.
    ISBN: 9781461464365
    Signatur Availability
    BibTip Others were also interested in ...
  • 5
    Keywords: Oncology ; Oncology   ; Toxicology ; Cancer Research ; Oncology ; Pharmacology/Toxicology ; Springer Nature Living Reference
    Abstract: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on.℗ The chapters are written by national or international experts and specialists.℗
    Pages: Approx. 800 p. 50 illus. : online resource.
    ISBN: 9789400777408
    Signatur Availability
    BibTip Others were also interested in ...
  • 6
    Call number: W160:26(2)
    Keywords: DKFZ-publications ; Signal Transduction / physiology ; Intracellular Signaling Peptides and Proteins / physiology
    Pages: xiii, 639 p. : ill.
    Edition: 2nd edition.
    ISBN: 9780815342151
    Signatur Availability
    W160:26(2) available
    BibTip Others were also interested in ...
  • 7
    facet.materialart.
    New York, NY : Springer
    Keywords: Oncology ; Oncology   ; Medical laboratories ; Internal Medicine ; Medicine ; Toxicology ; Cancer Research ; Oncology ; Laboratory Medicine ; Internal Medicine ; Molecular Medicine ; Pharmacology/Toxicology ; Springer Nature Living Reference
    Abstract: In the past decade, we have experienced an explosion of new information about cancer therapeutic targets. Many of the targets have been validated by the discovery and approval of new medicines which have been approved for the treatment of cancer. On the heels of these successes, innumerable new targets and new potential therapeutics are being developed by many different groups including government agencies, pharmaceutical companies, biotechnology companies, academic institutions, and individual investigators. Understanding the expanding "universe" of cancer therapies is therefore becoming impossible and no single source exists which serves as a reference for the involved parties. Further, the interested parties have vastly different areas of expertise, from focused laboratory based science, to clinical research, to corporate and regulatory oversight. The text would be updated every two years, more often depending on pace of change, interest and sales. While useful online, this reference book would likely be kept in hard copy as well
    Pages: 800 p. 164 illus., 64 illus. in color. : online resource.
    ISBN: 9781461466130
    Signatur Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...