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  • 1
    Keywords: Nucleic Acids ; Genetic Engineering ; Popular Life Sciences ; Nucleic Acid Chemistry ; Genetic Engineering ; Popular Science in Chemistry and Materials ; Springer eBooks
    Abstract: Carolyń€™s parents did not, after all, make genomics history by synthesizing her genome in a lab. She has known she is the "Human Hoax" ever since a high school genetics exercise revealed she has trisomy X€”á chromosomal abnormality€”ýet no synthetically constructed genome would have such clear traces of natural conception. Many years later, as molecular biologist, she hopes her colleagues never learn of her embarrassing origins. But when someone ransacks her office and lab, she finds professional embarrassment is the least of her worries. Someone believes she has the results of her parentś€™ last, secret experiments, and is willing to kill to get them. But all she has from her parents are their geneś€”can she find what else they may have left her before somebody else does? In a not-so-distant society, where corporations wield as much power as nations and the line between corporate employee and state authority is blurred, the chase is on. Carolyn may have just too little time at hand to unravel the mystery of her parentś€™ final days and to realize the deep consequences for the future of mankind. This fast-paced novel is followed by an extensive science chapter where the author provides a non-technical primer on modern genetics and on the speculative biology behind Carolyń€™s code. Dr V Anne Smith is on the biology faculty at the University of St Andrews in Scotland. She researches computational biology, concentrating on complex biological networks. She develops algorithms to infer functional interactions based upon observational data, generating biological discovery in areas as diverse as ecosystems and gene regulation. In addition to doing research, she enjoys writing science fiction stories. A Code for Carolyn is her first scientific novel
    Pages: V, 235 p. 6 illus. : online resource.
    ISBN: 9783030045531
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  • 2
    Keywords: Popular works ; Gene Expression ; Evolutionary Biology ; Medicine ; Health ; Popular Science ; Popular Life Sciences ; Evolutionary Biology ; Popular Science in Medicine and Health ; Gene Expression ; Springer eBooks
    Description / Table of Contents: Preface -- Part I: The Novel -- Part II: The Science behind the fiction
    Abstract: Genetics professor Michelle Murphy loses her husband under mysterious circumstances and without warning, while their brilliant eight-year-old daughter Avalon, adopted in Kazakhstan, stubbornly believes she is a mutant. As if this were not enough, she soon finds herself thrown into the middle of a quickly thickening plot, where the legacy of Genghis Khan meets the hunt for FOXP5, a genetic transcription factor that could herald the dawn of new human species. Initially caught helplessly between well-meaning fellow scientists, the government, and more sinister agents, Michelle eventually takes control with the help of a host of unlikely heroes and finds the courage to confront the decision of whether to save human lives or humanity. The scientific and technical aspects underlying the plot – in particular aspects of FOX proteins, genetic mutations, viruses, and cancer as well as the relation between intelligence and cortical complexity – are introduced and discussed by the authors in an extensive, non-technical appendix. Science writer Wallace Kaufman’s work has appeared in major magazines and newspapers in the U.S., England, and Kazakhstan. After Duke University he earned an M.Litt. from Oxford. His writing has taken him to Central and South America, to European Russia and the coasts of Siberia. He worked in most of Central Asia and served as resident adviser on housing and land reform in Kazakhstan. His books include Invasive Plants: Guide to Identification and the Impacts and Control of Common North American Species (2nd edition, 2013), Coming Out of the Woods - A Memoir (2001), No Turning Back (1994), and The Beaches Are Moving: The Drowning of America's Shoreline, (1979/1983). David Deamer is a Research Professor of Biomolecular Engineering at the University of California, Santa Cruz. He recently published First Life: Discovering the Connections between Stars, Cells, and How Life Began (2011). Deamer's research concerns molecular self-assembly processes related to the origin and evolution of membrane structure. Over the past 25 years, he has been engaged in developing nanoscopic pores in lipid bilayers as a way to sequence DNA. This work came to fruition in 2015 when the first portable nanopore sequencing device was successfully tested by early users
    Pages: VII, 251 p. 1 illus. in color. : online resource.
    ISBN: 9783319289618
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