CaRLO

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Publication Date: 2018-03-05

Description: Alzheimer’s disease (AD) is conceptualized as a progressive consequence of two hallmark pathological changes in grey matter: extracellular amyloid plaques and neurofibrillary tangles. However, over the past se...

Electronic ISSN: 2051-5960

Topics: Medicine

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2

Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry (2018)

Rémi Longuespée, Annika K. Wefers, Elena De Vita, Aubry K. Miller, David E. Reuss, Wolfgang Wick, Christel Herold-Mende, Mark Kriegsmann, Peter Schirmacher, Andreas von Deimling and Stefan Pusch

BioMed Central

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Publication Date: 2018-03-05

Description: All isocitrate dehydrogenase (IDH) mutant solid neoplasms exhibit highly elevated levels of D-2-hydroxyglutarate (D-2HG). Detection of 2HG in tumor tissues currently is performed by gas or liquid chromatograph...

Electronic ISSN: 2051-5960

Topics: Medicine

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3

Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease (2018)

Qi Zhang, Cheng Ma, Marla Gearing, Peng George Wang, Lih-Shen Chin and Lian Li

BioMed Central

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Publication Date: 2018-03-05

Description: Although the genetic causes for several rare, familial forms of Alzheimer’s disease (AD) have been identified, the etiology of the sporadic form of AD remains unclear. Here, we report a systems-level study of ...

Electronic ISSN: 2051-5960

Topics: Medicine

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4

CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival (2018)

P. S. Zeiner, J. Zinke, D. J. Kowalewski, S. Bernatz, J. Tichy, M. W. Ronellenfitsch, F. Thorsen, A. Berger, M. T. Forster, A. Muller, J. P. Steinbach, R. Beschorner, J. Wischhusen, H. M. Kvasnicka, K. H. Plate, S. Stefanović…

BioMed Central

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Publication Date: 2018-03-05

Description: Despite multidisciplinary local and systemic therapeutic approaches, the prognosis for most patients with brain metastases is still dismal. The role of adaptive and innate anti-tumor response including the Hum...

Electronic ISSN: 2051-5960

Topics: Medicine

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5

Three-dimensional analysis of synapses in the transentorhinal cortex of Alzheimer’s disease patients (2018)

M. Domínguez-Álvaro, M. Montero-Crespo, L. Blazquez-Llorca, R. Insausti, J. De; Felipe and L. Alonso-Nanclares

BioMed Central

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Publication Date: 2018-03-05

Description: Synaptic dysfunction or loss in early stages of Alzheimer’s disease (AD) is thought to be a major structural correlate of cognitive dysfunction. Early loss of episodic memory, which occurs at the early stage o...

Electronic ISSN: 2051-5960

Topics: Medicine

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6

Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA) (2018)

Michael Burwinkel, Manuel Lutzenberger, Frank L. Heppner, Walter Schulz-Schaeffer and Michael Baier

BioMed Central

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Publication Date: 2018-03-06

Description: Seeding and spread of beta-amyloid (Aβ) pathologies have been considered to be based on prion-like mechanisms. However, limited transmissibility of Aβ seeding activity upon peripheral exposure would represent ...

Electronic ISSN: 2051-5960

Topics: Medicine

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7

Scalable non-negative matrix tri-factorization (2018)

Andrej Čopar, Marinka žitnik and Blaž Zupan

BioMed Central

In: BioData Mining

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Publication Date: 2018-03-06

Description: Matrix factorization is a well established pattern discovery tool that has seen numerous applications in biomedical data analytics, such as gene expression co-clustering, patient stratification, and gene-disea...

Electronic ISSN: 1756-0381

Topics: Biology , Computer Science

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8

The role of facial pattern variation for species recognition in red-fronted lemurs (Eulemur rufifrons) (2018)

Hanitriniaina Rakotonirina, Peter M. Kappeler and Claudia Fichtel

BioMed Central

In: BMC Evolutionary Biology

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Publication Date: 2018-03-06

Description: Species recognition, i.e., the ability to distinguish conspecifics from heterospecifics, plays an essential role in reproduction. The role of facial cues for species recognition has been investigated in severa...

Electronic ISSN: 1471-2148

Topics: Biology

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9

Patients’ and caregivers’ experiences of using continuous glucose monitoring to support diabetes self-management: qualitative study (2018)

J. Lawton, M. Blackburn, J. Allen, F. Campbell, D. Elleri, L. Leelarathna, D. Rankin, M. Tauschmann, H. Thabit and R. Hovorka

BioMed Central

In: BMC Endocrine Disorders

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Publication Date: 2018-03-06

Description: Continuous glucose monitoring (CGM) enables users to view real-time interstitial glucose readings and provides information on the direction and rate of change of blood glucose levels. Users can also access his...

Electronic ISSN: 1472-6823

Topics: Medicine

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10

Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules (2018)

Unni Grimholt

BioMed Central

In: BMC Evolutionary Biology

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Publication Date: 2018-03-06

Description: In sharks, chickens, rats, frogs, medaka and zebrafish there is haplotypic variation in MHC class I and closely linked genes involved in antigen processing, peptide translocation and peptide loading. At least ...

Electronic ISSN: 1471-2148

Topics: Biology

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11

Disentangling the effect of illness perceptions on health status in people with type 2 diabetes after an acute coronary event (2018)

Rimke Cathelijne Vos, Marise Jeannine Kasteleyn, Monique Johanna Heijmans, Elke de Leeuw, François Georges Schellevis, Mieke Rijken and Guy Emile Rutten

BioMed Central

In: BMC Family Practice

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Publication Date: 2018-03-06

Description: Chronically ill patients such as people with type 2 diabetes develop perceptions of their illness, which will influence their coping behaviour. Perceptions are formed once a health threat has been recognised. ...

Electronic ISSN: 1471-2296

Topics: Medicine

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12

A single-center retrospective study of factors related to the effects of intravenous glucocorticoid therapy in moderate-to-severe and active thyroid-associated ophthalmopathy (2018)

Yang Wang, Shuo Zhang, Yidan Zhang, Xingtong Liu, Hao Gu, Sisi Zhong, Yazhuo Huang, Sijie Fang, Jing Sun, Huifang Zhou and Xianqun Fan

BioMed Central

In: BMC Endocrine Disorders

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Publication Date: 2018-03-06

Description: Intravenous glucocorticoids (ivGC) have been recommended as a first-line treatment of moderate-to-severe and active thyroid-associated ophthalmopathy (TAO). However, not all patients are responsive to ivGC. Th...

Electronic ISSN: 1472-6823

Topics: Medicine

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13

How well do general practitioners know their elderly patients’ social relations and feelings of loneliness? (2018)

Tina Drud Due, Håkon Sandholdt, Volkert Dirk Siersma and Frans Boch Waldorff

BioMed Central

In: BMC Family Practice

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Publication Date: 2018-03-06

Description: Social relationships are important to people and affect their quality of life, morbidity and mortality. The aim of this study was to examine the correlation between elderly patients’ descriptions of their soci...

Electronic ISSN: 1471-2296

Topics: Medicine

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14

Perceptions about screening for prostate cancer using genetic lifetime risk assessment: a qualitative study (2018)

Pia Kirkegaard, Adrian Edwards, Trine Laura Overgaard Nielsen, Torben Falck Ørntoft, Karina Dalsgaard Sørensen, Michael Borre and Flemming Bro

BioMed Central

In: BMC Family Practice

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Publication Date: 2018-03-06

Description: Most health authorities do not recommend screening for prostate cancer with PSA tests in asymptomatic patients who are not at increased risk. However, opportunistic screening for prostate cancer is still wante...

Electronic ISSN: 1471-2296

Topics: Medicine

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15

Correction to: Rate and determinants of non-adherence to a gluten-free diet and nutritional status assessment in children and adolescents with celiac disease in a tertiary Brazilian referral center: a cross-sectional and retrospective study (2018)

Maraci Rodrigues, Glauce Hiromi Yonamine and Carla Aline Fernandes Satiro

BioMed Central

In: BMC Gastroenterology

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Publication Date: 2018-03-06

Description: Unfortunately, after publication of this article [1], it was noticed that the names of the second and third authors were incorrectly displayed, respectively, as Glauce Hiromi Yonaminez and Carla Aline Satiro. ...

Electronic ISSN: 1471-230X

Topics: Medicine

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16

Combined activity of COX-1 and COX-2 is increased in non-neoplastic colonic mucosa from colorectal neoplasia patients (2018)

Thorbjørn Søren Rønn Jensen, Badar Mahmood, Morten Bach Damm, Marie Balslev Backe, Mattias Salling Dahllöf, Steen Seier Poulsen, Mark Berner Hansen and Niels Bindslev

BioMed Central

In: BMC Gastroenterology

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Publication Date: 2018-03-06

Description: Cyclooxygenase (COX) activity is increased in endoscopic normal colonic mucosa from patients with colorectal neoplasia (CRN). COX-2 is thought to be the predominant COX isozyme involved in neoplasia. Meanwhile...

Electronic ISSN: 1471-230X

Topics: Medicine

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17

Splash M-knife versus Flush Knife BT in the technical outcomes of endoscopic submucosal dissection for early gastric cancer: a propensity score matching analysis (2018)

Mitsuru Esaki, Sho Suzuki, Yasuyo Hayashi, Azusa Yokoyama, Shuichi Abe, Taizo Hosokawa, Haruei Ogino, Hirotada Akiho, Eikichi Ihara and Yoshihiro Ogawa

BioMed Central

In: BMC Gastroenterology

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Publication Date: 2018-03-06

Description: Endoscopic submucosal dissection (ESD) is a standard treatment for early gastric cancer. A new multi-functional ESD device was developed to achieve complete ESD with a single device. A metal plate attached to ...

Electronic ISSN: 1471-230X

Topics: Medicine

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18

Correction to: High density marker panels, SNPs prioritizing and accuracy of genomic selection (2018)

Ling-Yun Chang, Sajjad Toghiani, Ashley Ling, Sammy E. Aggrey and Romdhane Rekaya

BioMed Central

In: BMC Genetics

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Publication Date: 2018-03-06

Description: The original version of this article [1], published on 5 January 2018, contained 3 formatting errors. In this Correction the affected parts of the article are shown. The original article has been updated.

Electronic ISSN: 1471-2156

Topics: Biology

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19

Diversity of plant defense elicitor peptides within the Rosaceae (2018)

Cristina Ruiz, Anna Nadal, Laura Foix, Laura Montesinos, Emilio Montesinos and Maria Pla

BioMed Central

In: BMC Genetics

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Publication Date: 2018-03-06

Description: Plant elicitor peptides (Peps) are endogenous molecules that induce and amplify the first line of inducible plant defense, known as pattern-triggered immunity, contributing to protect plants against attack by ...

Electronic ISSN: 1471-2156

Topics: Biology

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20

Detecting TF-miRNA-gene network based modules for 5hmC and 5mC brain samples: a intra- and inter-species case-study between human and rhesus (2018)

Ujjwal Maulik, Sagnik Sen, Saurav Mallik and Sanghamitra Bandyopadhyay

BioMed Central

In: BMC Genetics

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Publication Date: 2018-03-06

Description: Study of epigenetics is currently a high-impact research topic. Multi stage methylation is also an area of high-dimensional prospect. In this article, we provide a new study (intra and inter-species study) on ...

Electronic ISSN: 1471-2156

Topics: Biology

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21

Video-calls to reduce loneliness and social isolation within care environments for older people: an implementation study using collaborative action research (2018)

Sonam Zamir, Catherine Hagan Hennessy, Adrian H Taylor and Ray B Jones

BioMed Central

In: BMC Geriatrics

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Publication Date: 2018-03-06

Description: Older people in care may be lonely with insufficient contact if families are unable to visit. Face-to-face contact through video-calls may help reduce loneliness, but little is known about the processes of eng...

Electronic ISSN: 1471-2318

Topics: Medicine

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22

Analysis of MAPK and MAPKK gene families in wheat and related Triticeae species (2018)

Ravinder K. Goyal, Dan Tulpan, Nora Chomistek, Dianevys González-Peña Fundora, Connor West, Brian E. Ellis, Michele Frick, André Laroche and Nora A. Foroud

BioMed Central

In: BMC Genomics

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Publication Date: 2018-03-06

Description: The mitogen-activated protein kinase (MAPK) family is involved in signal transduction networks that underpin many different biological processes in plants, ranging from development to biotic and abiotic stress...

Electronic ISSN: 1471-2164

Topics: Biology

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23

Are physiotherapists employing person-centred care for people with dementia? An exploratory qualitative study examining the experiences of people with dementia and their carers (2018)

Abigail J. Hall, Lisa Burrows, Iain A. Lang, Ruth Endacott and Victoria A. Goodwin

BioMed Central

In: BMC Geriatrics

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Publication Date: 2018-03-06

Description: People with dementia may receive physiotherapy for a variety of reasons. This may be for musculoskeletal conditions or as a result of falls, fractures or mobility difficulties. While previous studies have soug...

Electronic ISSN: 1471-2318

Topics: Medicine

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24

Access to primary care and computed tomography use in the emergency department (2018)

M. Fernanda Bellolio, Shawna D. Bellew, Lindsey R. Sangaralingham, Ronna L. Campbell, Daniel Cabrera, Molly M. Jeffery, Nilay D. Shah and Erik P. Hess

BioMed Central

In: BMC Health Services Research

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Publication Date: 2018-03-06

Description: The decision to obtain a computed tomography CT scan in the emergency department (ED) is complex, including a consideration of the risk posed by the test itself weighed against the importance of obtaining the ...

Electronic ISSN: 1472-6963

Topics: Medicine

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25

Polypharmacy in the oldest old (≥80 years of age) patients in China: a cross-sectional study (2018)

Xiaoxing Lai, Hongwei Zhu, Xiaopeng Huo and Zheng Li

BioMed Central

In: BMC Geriatrics

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Publication Date: 2018-03-06

Description: The oldest old generally have worse health and more comorbidities than the general population of older adults, and they are more likely to be exposed to polypharmacy. Reliable investigation of polypharmacy amo...

Electronic ISSN: 1471-2318

Topics: Medicine

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26

Community mobilization and maternal Care of Women Living with HIV in poor settings: the case of Mfuwe, Zambia (2018)

Choolwe Muzyamba, Wim Groot, Sonila Tomini and Milena Pavlova

BioMed Central

In: BMC Health Services Research

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Publication Date: 2018-03-06

Description: Research has shown that community mobilization is a useful strategy in promoting maternal care of HIV negative women in resource poor settings; however, similar evidence for women living with HIV is missing. T...

Electronic ISSN: 1472-6963

Topics: Medicine

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27

Selling my sheep to pay for medicines – household priorities and coping strategies in a setting without universal health coverage (2018)

Onarheim Kristine Husøy, Sisay Mitike Molla, Gizaw Muluken, Moland Karen Marie, Norheim Ole Frithof and Miljeteig Ingrid

BioMed Central

In: BMC Health Services Research

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Publication Date: 2018-03-06

Description: The first month of life is the period with the highest risk of dying. Despite knowledge of effective interventions, newborn mortality is high and utilization of health care services remains low in Ethiopia. In...

Electronic ISSN: 1472-6963

Topics: Medicine

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28

More is less, less is more, or does it really matter? The curious case of impact of azacitidine administration schedules on outcomes in patients with myelodysplastic syndromes (2018)

Rory M. Shallis and Amer M. Zeidan

BioMed Central

In: BMC Hematology

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Publication Date: 2018-03-06

Description: Myelodysplastic syndromes (MDS) encompass a diverse group of hematologic disorders characterized by ineffective and malignant hematopoiesis, peripheral cytopenias and significantly increased risk of progressio...

Electronic ISSN: 1471-2326

Topics: Medicine

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29

Pregnant mothers are more anemic than lactating mothers, a comparative cross-sectional study, Bahir Dar, Ethiopia (2018)

Berhanu Elfu Feleke and Teferi Elfu Feleke

BioMed Central

In: BMC Hematology

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Publication Date: 2018-03-06

Description: Information on the hemoglobin status of pregnant and lactating mothers was scarce. The objectives of this study were to determine the burden and determinants of anemia in the pregnant and lactating mother.

Electronic ISSN: 1471-2326

Topics: Medicine

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30

Beta-2 adrenergic receptors increase TREG cell suppression in an OVA-induced allergic asthma mouse model when mice are moderate aerobically exercised (2018)

Kari J. Dugger, Taylor Chrisman, Sarah L. Sayner, Parker Chastain, Kacie Watson and Robert Estes

BioMed Central

In: BMC Immunology

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Publication Date: 2018-03-06

Description: The potency of T regulatory (TREG) cells to inhibit T helper (Th)-driven immune cell responses has been linked to increased intracellular cyclic-AMP (cAMP) levels of TREG cells. In an ovalbumin (OVA)-driven al...

Electronic ISSN: 1471-2172

Topics: Medicine

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31

Down selecting adjuvanted vaccine formulations: a comparative method for harmonized evaluation (2018)

Sumera Y. Younis, Christophe Barnier-Quer, Simon Heuking, Vinod Sommandas, Livia Brunner, Nicole vd.Werff, Patrice Dubois, Martin Friede, Clemens Kocken, Nicolas Collin and Ed Remarque

BioMed Central

In: BMC Immunology

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Publication Date: 2018-03-06

Description: The need for rapid and accurate comparison of panels of adjuvanted vaccine formulations and subsequent rational down selection, presents several challenges for modern vaccine development. Here we describe a me...

Electronic ISSN: 1471-2172

Topics: Medicine

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32

Impact of a vaccination programme in children vaccinated with ProQuad, and ProQuad-specific effectiveness against varicella in the Veneto region of Italy (2018)

Carlo Giaquinto, Giovanni Gabutti, Vincenzo Baldo, Marco Villa, Lara Tramontan, Nadia Raccanello, Francesca Russo, Chiara Poma, Antonio Scamarcia, Luigi Cantarutti, Rebecca Lundin, Emilia Perinetti, Xavier Cornen, Stéphane Thomas, Céline Ballandras, Audrey Souverain…

BioMed Central

In: BMC Infectious Diseases

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Publication Date: 2018-03-06

Description: Monovalent varicella vaccines have been available in the Veneto Region of Italy since 2004. In 2006, a single vaccine dose was added to the immunisation calendar for children aged 14 months. ProQuad®, a quadri...

Electronic ISSN: 1471-2334

Topics: Medicine

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33

Treatment outcomes and factors affecting unsuccessful outcome among new pulmonary smear positive and negative tuberculosis patients in Anqing, China: a retrospective study (2018)

Yufeng Wen, Zhiping Zhang, Xianxiang Li, Dan Xia, Jun Ma, Yuanyuan Dong and Xinwei Zhang

BioMed Central

In: BMC Infectious Diseases

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Publication Date: 2018-03-06

Description: Monitoring the treatment outcomes of tuberculosis and determining the specific factors associated with unsuccessful treatment outcome are essential to evaluate the effectiveness of tuberculosis control program...

Electronic ISSN: 1471-2334

Topics: Medicine

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34

Household contact non-attendance of clinical evaluation for tuberculosis: a pilot study in a high burden district in South Africa (2018)

Gladys Kigozi, Michelle Engelbrecht, Christo Heunis and André Janse van Rensburg

BioMed Central

In: BMC Infectious Diseases

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Publication Date: 2018-03-06

Description: In 2012, the World Health Organization launched guidelines for systematically investigating contacts of persons with infectious tuberculosis (TB) in low- and middle-income countries. As such, it is necessary t...

Electronic ISSN: 1471-2334

Topics: Medicine

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35

Socioeconomic and environmental determinants of under-five mortality in Gamo Gofa Zone, Southern Ethiopia: a matched case control study (2018)

Girma Temam Shifa, Ahmed Ali Ahmed and Alemayehu Worku Yalew

BioMed Central

In: BMC International Health and Human Rights

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Publication Date: 2018-03-06

Description: Despite global declaration of the right to life as a fundamental human right and substantial progress in reducing childhood mortality, unacceptably high number of children still die before their fifth birthday...

Electronic ISSN: 1472-698X

Topics: Medicine , Law

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36

Correction to: An audit of clinical training exposure amongst junior doctors working in Trauma & Orthopaedic Surgery in 101 hospitals in the United Kingdom (2018)

Mustafa S. Rashid

BioMed Central

In: BMC Medical Education

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Publication Date: 2018-03-06

Description: Following publication of the original article [1], the corresponding author wrote to say that he had missed the names of some of the collaborators in the list he sent to the typesetters. In addition, there was...

Electronic ISSN: 1472-6920

Topics: Medicine , Education

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37

Matters to address prior to introducing new life support technology in Japan: three serious ethical concerns related to the use of left ventricular assist devices as destination therapy and suggested policies to deal with them (2018)

Atsushi Asai, Sakiko Masaki, Taketoshi Okita, Aya Enzo and Yasuhiro Kadooka

BioMed Central

In: BMC Medical Ethics

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Publication Date: 2018-03-06

Description: Destination therapy (DT) is the permanent implantation of a left ventricular assist device (LVAD) in patients with end-stage, severe heart failure who are ineligible for heart transplantation. DT improves both...

Electronic ISSN: 1472-6939

Topics: Medicine , Philosophy

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38

Rules of engagement: perspectives on stakeholder engagement for genomic biobanking research in South Africa (2018)

Ciara Staunton, Paulina Tindana, Melany Hendricks and Keymanthri Moodley

BioMed Central

In: BMC Medical Ethics

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Publication Date: 2018-03-06

Description: Genomic biobanking research is undergoing exponential growth in Africa raising a host of legal, ethical and social issues. Given the scientific complexity associated with genomics, there is a growing recogniti...

Electronic ISSN: 1472-6939

Topics: Medicine , Philosophy

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39

Medical genomics at Belyaev Conference – 2017 (2018)

Yuriy L. Orlov, Julio R. Fernandez-Masso, Ming Chen and Ancha V. Baranova

BioMed Central

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Publication Date: 2018-03-06

Electronic ISSN: 1755-8794

Topics: Medicine

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40

A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy (2018)

Claudia Tamar Silva, Irina V. Zorkoltseva, Maartje N. Niemeijer, Marten E. van den Berg, Najaf Amin, Ayşe Demirkan, Elisa van Leeuwen, Adriana I. Iglesias, Laura B. Piñeros-Hernández, Carlos M. Restrepo, Jan A. Kors, Anatoly V. Kirichenko, Rob Willemsen, Ben A. Oostra, Bruno H. Stricker, André G. Uitterlinden…

BioMed Central

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Publication Date: 2018-03-06

Description: Electrocardiographic measures of left ventricular hypertrophy (LVH) are used as predictors of cardiovascular risk. We combined linkage and association analyses to discover novel rare genetic variants involved ...

Electronic ISSN: 1755-8794

Topics: Medicine

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41

Whole transcriptome analysis reveals differential gene expression profile reflecting macrophage polarization in response to influenza A H5N1 virus infection (2018)

Na Zhang, Yun-Juan Bao, Amy Hin-Yan Tong, Scott Zuyderduyn, Gary D. Bader, J. S. Malik Peiris, Si Lok and Suki Man-Yan Lee

BioMed Central

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Publication Date: 2018-03-06

Description: Avian influenza A H5N1 virus can cause lethal disease in humans. The virus can trigger severe pneumonia and lead to acute respiratory distress syndrome. Data from clinical, in vitro and in vivo suggest that vi...

Electronic ISSN: 1755-8794

Topics: Medicine

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42

What to consider when pseudohypoparathyroidism is ruled out: iPPSD and differential diagnosis (2018)

Arrate Pereda, Intza Garin and Guiomar Perez de Nanclares

BioMed Central

In: BMC Medical Genetics

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Publication Date: 2018-03-06

Description: Pseudohypoparathyroidism (PHP) is a rare disease whose phenotypic features are rather difficult to identify in some cases. Thus, although these patients may present with the Albright’s hereditary osteodystroph...

Electronic ISSN: 1471-2350

Topics: Biology , Medicine

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43

Incidental finding of large pneumothorax on Cardiac MR scan (2018)

J. P. M. Andrews, G. McKillop and M. R. Dweck

BioMed Central

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Publication Date: 2018-03-06

Description: We believe this is the first case report of a pneumothorax being identified using cardiac magnetic resonance imaging. This case also illustrates the haemodynamic effect a large pneumothorax can have on right v...

Electronic ISSN: 1471-2342

Topics: Biology

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44

Primary microcephaly case from the Karachay-Cherkess Republic poses an additional support for microcephaly and Seckel syndrome spectrum disorders (2018)

Andrey V. Marakhonov, Fedor A. Konovalov, Amin Kh. Makaov, Tatyana A. Vasilyeva, Vitaly V. Kadyshev, Varvara A. Galkina, Elena L. Dadali, Sergey I. Kutsev and Rena A. Zinchenko

BioMed Central

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Publication Date: 2018-03-06

Description: Primary microcephaly represents an example of clinically and genetically heterogeneous condition. Here we describe a case of primary microcephaly from the Karachay-Cherkess Republic, which was initially diagno...

Electronic ISSN: 1755-8794

Topics: Medicine

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45

Presentation of laboratory test results in patient portals: influence of interface design on risk interpretation and visual search behaviour (2018)

Paolo Fraccaro, Markel Vigo, Panagiotis Balatsoukas, Sabine N. van der Veer, Lamiece Hassan, Richard Williams, Grahame Wood, Smeeta Sinha, Iain Buchan and Niels Peek

BioMed Central

In: BMC Medical Informatics and Decision Making

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Publication Date: 2018-03-06

Description: Patient portals are considered valuable instruments for self-management of long term conditions, however, there are concerns over how patients might interpret and act on the clinical information they access. W...

Electronic ISSN: 1472-6947

Topics: Computer Science , Medicine

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46

Investigations of organ and effective doses of abdominal cone-beam computed tomography during transarterial chemoembolization using Monte Carlo simulation (2018)

Yi-Shuan Hwang, Hui-Yu Tsai, Yu-Ying Lin and Kar-Wai Lui

BioMed Central

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Publication Date: 2018-03-06

Description: To investigate the organ dose, effective dose (ED), conversion factor, and the C-arm rotation angle effects on dose variations of abdominal C-arm cone-beam computed tomography (CBCT) during transarterial chemo...

Electronic ISSN: 1471-2342

Topics: Biology

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47

Systemic air embolism after percutaneous computed tomography-guided lung biopsy due to a kink in the coaxial biopsy system: a case report (2018)

Hsu-Chao Chang and Mei-Chen Yang

BioMed Central

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Publication Date: 2018-03-06

Description: Systemic air embolism is a rare but potentially life-threatening complication of percutaneous computed tomography (CT)-guided lung biopsy. The incidence might be underestimated because of failure to diagnose t...

Electronic ISSN: 1471-2342

Topics: Biology

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48

Cardiovascular magnetic resonance in the evaluation of heart valve disease (2018)

G. S. Gulsin, A. Singh and G. P. McCann

BioMed Central

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Publication Date: 2018-03-06

Description: Over the last 25 years, cardiovascular magnetic resonance imaging (CMR) has emerged as an alternative to echocardiography for assessment of valvular heart disease (VHD). Although echo remains the first-line im...

Electronic ISSN: 1471-2342

Topics: Biology

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49

The morphology of maxillary first and second molars analyzed by cone-beam computed tomography in a polish population (2018)

Katarzyna Olczak and Halina Pawlicka

BioMed Central

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Publication Date: 2018-03-06

Description: The success of endodontic treatment is greatly affected by the location of the root canals. The purpose of this study was to evaluate the root and canal morphology of permanent maxillary first and second molar...

Electronic ISSN: 1471-2342

Topics: Biology

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50

Effective behavioral intervention strategies using mobile health applications for chronic disease management: a systematic review (2018)

Jung-Ah Lee, Mona Choi, Sang A Lee and Natalie Jiang

BioMed Central

In: BMC Medical Informatics and Decision Making

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Publication Date: 2018-03-06

Description: Mobile health (mHealth) has continuously been used as a method in behavioral research to improve self-management in patients with chronic diseases. However, the evidence of its effectiveness in chronic disease...

Electronic ISSN: 1472-6947

Topics: Computer Science , Medicine

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51

Combining information from a clinical data warehouse and a pharmaceutical database to generate a framework to detect comorbidities in electronic health records (2018)

Emmanuelle Sylvestre, Guillaume Bouzillé, Emmanuel Chazard, Cécil His-Mahier, Christine Riou and Marc Cuggia

BioMed Central

In: BMC Medical Informatics and Decision Making

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Publication Date: 2018-03-06

Description: Medical coding is used for a variety of activities, from observational studies to hospital billing. However, comorbidities tend to be under-reported by medical coders. The aim of this study was to develop an a...

Electronic ISSN: 1472-6947

Topics: Computer Science , Medicine

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52

Investigating the parameter space of evolutionary algorithms (2018)

Moshe Sipper, Weixuan Fu, Karuna Ahuja and Jason H. Moore

BioMed Central

In: BioData Mining

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Publication Date: 2018-03-06

Description: Evolutionary computation (EC) has been widely applied to biological and biomedical data. The practice of EC involves the tuning of many parameters, such as population size, generation count, selection size, an...

Electronic ISSN: 1756-0381

Topics: Biology , Computer Science

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53

Identification of influential observations in high-dimensional cancer survival data through the rank product test (2018)

Eunice Carrasquinha, André Veríssimo, Marta B. Lopes and Susana Vinga

BioMed Central

In: BioData Mining

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Publication Date: 2018-03-06

Description: Survival analysis is a statistical technique widely used in many fields of science, in particular in the medical area, and which studies the time until an event of interest occurs. Outlier detection in this co...

Electronic ISSN: 1756-0381

Topics: Biology , Computer Science

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54

Complete genomic sequences of Propionibacterium freudenreichii phages from Swiss cheese reveal greater diversity than Cutibacterium (formerly Propionibacterium) acnes phages (2018)

Lucy Cheng, Laura J. Marinelli, Noël Grosset, Sorel T. Fitz-Gibbon, Charles A. Bowman, Brian Q. Dang, Daniel A. Russell, Deborah Jacobs-Sera, Baochen Shi, Matteo Pellegrini, Jeff F. Miller, Michel Gautier, Graham F. Hatfull and Robert L. Modlin

BioMed Central

In: BMC Microbiology

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Publication Date: 2018-03-06

Description: A remarkable exception to the large genetic diversity often observed for bacteriophages infecting a specific bacterial host was found for the Cutibacterium acnes (formerly Propionibacterium acnes) phages, which a...

Electronic ISSN: 1471-2180

Topics: Biology

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55

Porphyromonas gingivalis ATCC 33277 promotes intercellular adhesion molecule-1 expression in endothelial cells and monocyte-endothelial cell adhesion through macrophage migration inhibitory factor (2018)

Wanyue Xu, Yaping Pan, Qiufang Xu, Yun Wu, Jiayu Pan, Jingya Hou, Li Lin, Xiaolin Tang, Chen Li, Jingbo Liu and Dongmei Zhang

BioMed Central

In: BMC Microbiology

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Publication Date: 2018-03-06

Description: Porphyromonas gingivalis (P. gingivalis), one of the main pathogenic bacteria involved in periodontitis, induces the expression of intercellular adhesion molecule − 1 (ICAM-1) and monocyte-endothelial cell adhesi...

Electronic ISSN: 1471-2180

Topics: Biology

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56

Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis (2018)

Oddvar Oppegaard, Haima Mylvaganam, Steinar Skrede and Bård Reiakvam Kittang

BioMed Central

In: BMC Microbiology

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Publication Date: 2018-03-06

Description: During the past decades, Streptococcus dysgalactiae subspecies equisimilis (SDSE) has been increasingly recognized as an important human pathogen. Osteoarticular infections is one of the predominant disease manif...

Electronic ISSN: 1471-2180

Topics: Biology

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57

Grade III bone cement implantation syndrome in malignant lung cancer patient: a case report (2018)

Pawan Kumar Hamal, Puspa Raj Poudel and Janith Singh

BioMed Central

In: BMC Anesthesiology

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Publication Date: 2018-03-06

Description: Bone cement implantation syndrome is a known complication causing mortality during perioperative period particularly in patients with malignancy. With rise in aging population with malignancy in low income cou...

Electronic ISSN: 1471-2253

Topics: Medicine

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58

Impact of the introduction of an endotracheal tube attachment device on the incidence and severity of oral pressure injuries in the intensive care unit: a retrospective observational study (2018)

Jaye Hampson, Cameron Green, Joanne Stewart, Lauren Armitstead, Gemma Degan, Andrea Aubrey, Eldho Paul and Ravindranath Tiruvoipati

BioMed Central

In: BMC Nursing

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Publication Date: 2018-03-06

Description: Endotracheal tube (ETT) fasteners such as the AnchorFast™ claim to assist with the prevention of oral pressure injuries in intubated patients, however evidence to support their clinical efficacy is limited. Th...

Electronic ISSN: 1472-6955

Topics: Medicine

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59

The fast exodrift after the first surgical treatment of exotropia and its correlation with surgical outcome of second surgery (2018)

Won Jae Kim and Myung Mi Kim

BioMed Central

In: BMC Ophthalmology

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Publication Date: 2018-03-06

Description: To compare the rate of exodrift after a second surgery for recurrent exotropia, in patients grouped to fast versus slow exodrift after their first surgery. To determine whether there is a correlation with surg...

Electronic ISSN: 1471-2415

Topics: Medicine

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60

Developing and evaluating an instrument to measure Recovery After INtensive care: the RAIN instrument (2018)

Ingegerd Bergbom, Veronika Karlsson and Mona Ringdal

BioMed Central

In: BMC Nursing

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Publication Date: 2018-03-06

Description: Measuring and evaluating patients' recovery, following intensive care, is essential for assessing their recovery process. By using a questionnaire, which includes spiritual and existential aspects, possibiliti...

Electronic ISSN: 1472-6955

Topics: Medicine

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61

Lessons learnt in recruiting disadvantaged families to a birth cohort study (2018)

Amit Arora, Narendar Manohar, Dina Bedros, Anh Phong David Hua, Steven Yu Hsiang You, Victoria Blight, Shilpi Ajwani, John Eastwood and Sameer Bhole

BioMed Central

In: BMC Nursing

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Publication Date: 2018-03-06

Description: Dental decay in early childhood can be prevented by a model based on shared care utilising members of primary care team such as Child and Family Health Nurses (CFHNs) in health promotion and early intervention...

Electronic ISSN: 1472-6955

Topics: Medicine

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62

Reasons for reported suspicion of child maltreatment and responses from the child welfare - a cross-sectional study of Norwegian public dental health personnel (2018)

Ingfrid Vaksdal Brattabø, Ragnhild Bjørknes and Anne Nordrehaug Åstrøm

BioMed Central

In: BMC Oral Health

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Publication Date: 2018-03-06

Description: To prevent child maltreatment, the identification of vulnerable children is essential. In Norway, public dental health personnel (PDHP) report suspicion of child maltreatment to child welfare services (CWS) at...

Electronic ISSN: 1472-6831

Topics: Medicine

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63

Temporary employment and tooth loss: a cross-sectional study from the J-SHINE study (2018)

Yukihiro Sato, Toru Tsuboya, Richard G. Watt, Jun Aida and Ken Osaka

BioMed Central

In: BMC Oral Health

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Publication Date: 2018-03-06

Description: Temporary employment leads to psychological distress and higher mortality, but data on its associations with oral health is limited. We examined whether having the experience of temporary employment was associ...

Electronic ISSN: 1472-6831

Topics: Medicine

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64

Reliability and validity of measuring scale for postoperative complications in third molar surgery (2018)

Pedro Christian Aravena, Paula Astudillo, Horacio Miranda and Carlos Manterola

BioMed Central

In: BMC Oral Health

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Publication Date: 2018-03-06

Description: Third molar removal surgery is the most frequently performed surgery in the oral and maxillofacial field with a wide range of items in the quantification of postoperative complications. For their measure, in 2...

Electronic ISSN: 1472-6831

Topics: Medicine

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65

“Never at ease” – family carers within integrated palliative care: a multinational, mixed method study (2018)

Gülay Ateş, Anne Frederieke Ebenau, Csilla Busa, Ágnes Csikos, Jeroen Hasselaar, Birgit Jaspers, Johan Menten, Sheila Payne, Karen Van Beek, Sandra Varey, Marieke Groot and Lukas Radbruch

BioMed Central

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Publication Date: 2018-03-06

Description: Family carers manage a wide range of responsibilities in the lives and care of patients receiving palliative care. They fulfil multiple roles and perform activities within different settings. This has immediat...

Electronic ISSN: 1472-684X

Topics: Medicine

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66

Indicators for early assessment of palliative care in lung cancer patients: a population study using linked health data (2018)

Maria Kelly, Katie M. O’Brien, Michael Lucey, Kerri Clough-Gorr and Ailish Hannigan

BioMed Central

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Publication Date: 2018-03-06

Description: Analysing linked, routinely collected data may be useful to identify characteristics of patients with suspected lung cancer who could benefit from early assessment for palliative care. The aim of this study wa...

Electronic ISSN: 1472-684X

Topics: Medicine

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67

Development of the Japanese version of an information aid to provide accurate information on prognosis to patients with advanced non–small-cell lung cancer receiving chemotherapy: a pilot study (2018)

Kikuo Nakano, Yoshihiro Kitahara, Mineyo Mito, Misato Seno and Shoji Sunada

BioMed Central

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Publication Date: 2018-03-06

Description: Without explicit prognostic information, patients may overestimate their life expectancy and make poor choices at the end of life. We sought to design the Japanese version of an information aid (IA) to provide...

Electronic ISSN: 1472-684X

Topics: Medicine

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68

Hand grip strength and maximum peak expiratory flow: determinants of bone mineral density of adolescent students (2018)

Marco Cossio-Bolaños, Cynthia Lee-Andruske, Miguel de Arruda, Cristian Luarte-Rocha, Alejandro Almonacid-Fierro and Rossana Gómez-Campos

BioMed Central

In: BMC Pediatrics

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Publication Date: 2018-03-06

Description: Maintaining and building healthy bones during the lifetime requires a complicated interaction between a number of physiological and lifestyle factors. Our goal of this study was to analyze the association betw...

Electronic ISSN: 1471-2431

Topics: Medicine

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69

The family talk intervention in palliative care: a study protocol (2018)

Rakel Eklund, Ulrika Kreicbergs, Anette Alvariza and Malin Lövgren

BioMed Central

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Publication Date: 2018-03-06

Description: In palliative care contexts, support programs for families with a severely ill parent and minor children are few, and even fewer have been evaluated scientifically. The aims of this study are to examine feasib...

Electronic ISSN: 1472-684X

Topics: Medicine

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70

Hospital readmissions with acute infectious diseases in New Zealand children (2018)

Silvia Seibt, Catherine A. Gilchrist, Peter W. Reed, Emma J. Best, Anthony Harnden, Carlos A. Camargo Jr and Cameron C. Grant

BioMed Central

In: BMC Pediatrics

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Publication Date: 2018-03-06

Description: Infectious diseases are the leading cause of hospital admissions in young children. Hospitalisation with an infectious disease is a recurrent event for some children. Our objective was to describe risk factors...

Electronic ISSN: 1471-2431

Topics: Medicine

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71

Extragonadal germ cell tumor of the posterior mediastinum in a child complicated with spinal cord compression: a case report (2018)

Dong Keon Yon, Tae Keun Ahn, Dong Eun Shin, Gwang Il Kim and Moon Kyu Kim

BioMed Central

In: BMC Pediatrics

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Publication Date: 2018-03-06

Description: Germ cell tumors (GCTs) in children are rare neoplasms with diverse pathological findings according to the site and age of presentation. The most common symptoms in children with mediastinal GCTs, which are no...

Electronic ISSN: 1471-2431

Topics: Medicine

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72

Claudin expression during early postnatal development of the murine cochlea (2018)

Takayuki Kudo, Philine Wangemann and Daniel C. Marcus

BioMed Central

In: BMC Physiology

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Publication Date: 2018-03-06

Description: Claudins are major components of tight junctions, which form the paracellular barrier between the cochlear luminal and abluminal fluid compartments that supports the large transepithelial voltage difference an...

Electronic ISSN: 1472-6793

Topics: Medicine

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73

Regulation of Locomotor activity in fed, fasted, and food-restricted mice lacking tissue-type plasminogen activator (2018)

Jessica A. Krizo, Linley E. Moreland, Ashutosh Rastogi, Xiang Mou, Rebecca A. Prosser and Eric M. Mintz

BioMed Central

In: BMC Physiology

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Publication Date: 2018-03-06

Description: Circadian rhythms of physiology and behavior are driven by a circadian clock located in the suprachiasmatic nucleus of the hypothalamus. This clock is synchronized to environmental day/night cycles by photic i...

Electronic ISSN: 1472-6793

Topics: Medicine

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74

Adiponectin is required for maintaining normal body temperature in a cold environment (2018)

Qiong Wei, Jong Han Lee, Hongying Wang, Odelia Y. N. Bongmba, Chia-Shan Wu, Geetali Pradhan, Zilin Sun, Lindsey Chew, Mandeep Bajaj, Lawrence Chan, Robert S. Chapkin, Miao-Hsueh Chen and Yuxiang Sun

BioMed Central

In: BMC Physiology

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Publication Date: 2018-03-06

Description: Thermogenic impairment promotes obesity and insulin resistance. Adiponectin is an important regulator of energy homeostasis. While many beneficial metabolic effects of adiponectin resemble that of activated th...

Electronic ISSN: 1472-6793

Topics: Medicine

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75

Association of yield-related traits in founder genotypes and derivatives of common wheat (Triticum aestivum L.) (2018)

Jie Guo, Weiping Shi, Zheng Zhang, Jingye Cheng, Daizhen Sun, Jin Yu, Xinlei Li, Pingyi Guo and Chenyang Hao

BioMed Central

In: BMC Plant Biology

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Publication Date: 2018-03-06

Description: Yield improvement is an ever-important objective of wheat breeding. Studying and understanding the phenotypes and genotypes of yield-related traits has potential for genetic improvement of crops.

Electronic ISSN: 1471-2229

Topics: Biology

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76

Three endoplasmic reticulum-associated fatty acyl-coenzyme a reductases were involved in the production of primary alcohols in hexaploid wheat (Triticum aestivum L.) (2018)

Guaiqiang Chai, Chunlian Li, Feng Xu, Yang Li, Xue Shi, Yong Wang and Zhonghua Wang

BioMed Central

In: BMC Plant Biology

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Publication Date: 2018-03-06

Description: The cuticle covers the surface of the polysaccharide cell wall of leaf epidermal cells and forms an essential diffusion barrier between the plant and the environment. The cuticle is composed of cutin and wax. ...

Electronic ISSN: 1471-2229

Topics: Biology

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77

Who is the gate keeper for treatment in a fertility clinic in Germany? -baseline results of a prospective cohort study (PinK study)- (2018)

Eva Münster, Stephan Letzel, Jasmin Passet-Wittig, Norbert F. Schneider, Bettina Schuhrke, Rudolf Seufert and Ulrike Zier

BioMed Central

In: BMC Pregnancy and Childbirth

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Publication Date: 2018-03-06

Description: It is estimated that 5-15% of all couples in industrialised nations are infertile. A perceived unfulfilled desire for a child or self-identification as infertile can lead to psychological strain and social iso...

Electronic ISSN: 1471-2393

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78

Correction to: Identification of tRNA nucleoside modification genes critical for stress response and development in rice and Arabidopsis (2018)

Youmei Wang, Chaoqun Pang, Xukai Li, Zhen Hu, Zhengyi Lv, Bo Zheng and Peng Chen

BioMed Central

In: BMC Plant Biology

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Publication Date: 2018-03-06

Description: Following publication of the original article [1], the authors reported that there was a mistake in the presentation of their funding information. The sentence “This study was supported by the National Natural...

Electronic ISSN: 1471-2229

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79

Oxidative stress and endothelial function in normal pregnancy versus pre-eclampsia, a combined longitudinal and case control study (2018)

Dominique Mannaerts, Ellen Faes, Jan Gielis, Emeline Van Craenenbroeck, Paul Cos, Marc Spaanderman, Wilfried Gyselaers, Jerome Cornette and Yves Jacquemyn

BioMed Central

In: BMC Pregnancy and Childbirth

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Publication Date: 2018-03-06

Description: Pre-eclampsia (PE) is related to an impaired endothelial function. Endothelial dysfunction accounts for altered vascular reactivity, activation of the coagulation cascade and loss of vascular integrity. Impair...

Electronic ISSN: 1471-2393

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80

Critical race theory as a bridge in science training: the California State University, Northridge BUILD PODER program (2018)

Carrie L. Saetermoe, Gabriela Chavira, Crist S. Khachikian, David Boyns and Beverly Cabello

BioMed Central

In: BMC Proceedings

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Publication Date: 2018-03-06

Description: Unconscious bias and explicit forms of discrimination continue to pervade academic institutions. Multicultural and diversity training activities have not been sufficient in making structural and social changes...

Electronic ISSN: 1753-6561

Topics: Medicine

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81

Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients – a randomized controlled trial: study protocol (2018)

Manuel Föcker, Jochen Antel, Corinna Grasemann, Dagmar Führer, Nina Timmesfeld, Dana Öztürk, Triinu Peters, Anke Hinney, Johannes Hebebrand and Lars Libuda

BioMed Central

In: BMC Psychiatry

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Publication Date: 2018-03-06

Description: Depression is a significant health and economic burden worldwide affecting not only adults but also children and adolescents. Current treatment options for this group are scarce and show moderate effect sizes....

Electronic ISSN: 1471-244X

Topics: Medicine

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82

Community-based maternal, newborn, and child health surveillance: perceptions and attitudes of local stakeholders towards using mobile phone by village health volunteers in the Kenge Health Zone, Democratic Republic of Congo (2018)

Mulamba Diese, Albert Kalonji, Bibiche Izale, Susie Villeneuve, Ngoma Miezi Kintaudi, Guy Clarysse, Ngashi Ngongo and Abel Mukengeshayi Ntambue

BioMed Central

In: BMC Public Health

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Publication Date: 2018-03-06

Description: In early 2016, we implemented a community-based maternal, newborn, and child health (MNCH) surveillance using mobile phones to collect, analyze, and use data by village health volunteers (VHV) in Kenge Health ...

Electronic ISSN: 1471-2458

Topics: Medicine

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83

Progress towards the UNAIDS 90–90-90 goals by age and gender in a rural area of KwaZulu-Natal, South Africa: a household-based community cross-sectional survey (2018)

Helena Huerga, Gilles Van Cutsem, Jihane Ben Farhat, Adrian Puren, Malika Bouhenia, Lubbe Wiesner, Linda Dlamini, David Maman, Tom Ellman and Jean-François Etard

BioMed Central

In: BMC Public Health

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Publication Date: 2018-03-06

Description: The Joint United Nations Programme on HIV/AIDS (UNAIDS) has developed an ambitious strategy to end the AIDS epidemic. After eight years of antiretroviral therapy (ART) program we assessed progress towards the ...

Electronic ISSN: 1471-2458

Topics: Medicine

Published by BioMed Central

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84

Intensive home treatment for patients in acute psychiatric crisis situations: a multicentre randomized controlled trial (2018)

Jurgen Cornelis, Ansam Barakat, Jack Dekker, Tessy Schut, Sandra Berk, Hans Nusselder, Nikander Ruhl, Jeroen Zoeteman, Rien Van, Aartjan Beekman and Matthijs Blankers

BioMed Central

In: BMC Psychiatry

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Publication Date: 2018-03-06

Description: Hospitalization is a common method to intensify care for patients experiencing a psychiatric crisis. A short-term, specialised, out-patient crisis intervention by a Crisis Resolution Team (CRT) in the Netherla...

Electronic ISSN: 1471-244X

Topics: Medicine

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85

RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs (2018)

Jiyoun Yeo, Diego A. Morales, Tian Chen, Erin L. Crawford, Xiaolu Zhang, Thomas M. Blomquist, Albert M. Levin, Pierre P. Massion, Douglas A. Arenberg, David E. Midthun, Peter J. Mazzone, Steven D. Nathan, Ronald J. Wainz, Patrick Nana-Sinkam, Paige F. S. Willey, Taylor J. Arend…

BioMed Central

In: BMC Pulmonary Medicine

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Publication Date: 2018-03-06

Description: There is a need for more powerful methods to identify low-effect SNPs that contribute to hereditary COPD pathogenesis. We hypothesized that SNPs contributing to COPD risk through cis-regulatory effects are enrich...

Electronic ISSN: 1471-2466

Topics: Medicine

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86

Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension (2018)

Mario Boehm, Nadine Arnold, Adam Braithwaite, Josephine Pickworth, Changwu Lu, Tatyana Novoyatleva, David G. Kiely, Friedrich Grimminger, Hossein A. Ghofrani, Norbert Weissmann, Werner Seeger, Allan Lawrie, Ralph T. Schermuly and Baktybek Kojonazarov

BioMed Central

In: BMC Pulmonary Medicine

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Publication Date: 2018-03-06

Description: Aldosterone is a mineralocorticoid hormone critically involved in arterial blood pressure regulation. Although pharmacological aldosterone antagonism reduces mortality and morbidity among patients with severe ...

Electronic ISSN: 1471-2466

Topics: Medicine

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87

A structural preview of aquaporin 8 via homology modeling of seven vertebrate isoforms (2018)

Andreas Kirscht, Yonathan Sonntag, Per Kjellbom and Urban Johanson

BioMed Central

In: BMC Structural Biology

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Publication Date: 2018-03-06

Description: Aquaporins (AQPs) facilitate the passage of small neutral polar molecules across membranes of the cell. In animals there are four distinct AQP subfamilies, whereof AQP8 homologues constitute one of the smalles...

Electronic ISSN: 1472-6807

Topics: Biology

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88

Rosetta Broker for membrane protein structure prediction: concentrative nucleoside transporter 3 and corticotropin-releasing factor receptor 1 test cases (2018)

Dorota Latek

BioMed Central

In: BMC Structural Biology

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Publication Date: 2018-03-06

Description: Membrane proteins are difficult targets for structure prediction due to the limited structural data deposited in Protein Data Bank. Most computational methods for membrane protein structure prediction are base...

Electronic ISSN: 1472-6807

Topics: Biology

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89

Assessing short evolution brucellosis in a highly brucella endemic cattle keeping population of Western Uganda: a complementary use of Rose Bengal test and IgM rapid diagnostic test (2018)

Arnold Ezama, Jean-Paul Gonzalez, Samuel Majalija and Francis Bajunirwe

BioMed Central

In: BMC Public Health

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Publication Date: 2018-03-06

Description: Brucellosis is a worldwide and zoonotic disease often sadly misdiagnosed in endemic areas. Challenges of availability and accessibility of diagnostic tools are common in resource constrained populations where ...

Electronic ISSN: 1471-2458

Topics: Medicine

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