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  • Toxikologie
  • Biomedizin
  • Strömungsmechanik
  • Sage Publications  (14)
  • German Medical Science GMS Publishing House; Düsseldorf
  • American Institute of Physics (AIP)
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  • 1
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  GMS German Medical Science; VOL: 13; DOC09 /20150709/
    Publication Date: 2015-07-10
    Description: Understanding the toxic effects of xenobiotics requires sound knowledge of physiology and biochemistry. The often described lack of understanding pharmacology/toxicology is therefore primarily caused by the general absence of the necessary fundamental knowledge. Since toxic effects depend on exposure (or dosage) assessing the risks arising from toxic substances also requires quantitative reasoning. Typically public discussions nearly always neglect quantitative aspects and laypersons tend to disregard dose-effect-relationships. One of the main reasons for such disregard is the fact that exposures often occur at extremely low concentrations that can only be perceived intellectually but not by the human senses. However, thresholds in the low exposure range are often scientifically disputed. At the same time, ignorance towards known dangers is wide-spread. Thus, enhancing the risk competence of laypersons will have to be initially restricted to increasing the awareness of existing problems.
    Description: Das Verständnis der toxischen Wirkungen von Stoffen setzt ein gutes Verständnis der Physiologie bzw. Biochemie voraus. Das häufig beschriebene mangelnde Verständnis in der Bevölkerung für die Pharmakologie und Toxikologie beruht deshalb zu einem großen Teil auf den mangelnden Kenntnissen der erforderlichen Grundlagen. Toxische Wirkungen sind dosisabhängig, die Einschätzung von Risiken durch toxische Stoffe setzt also quantitatives Denken voraus. Da öffentliche Diskussionen aber fast immer die quantitativen Aspekte weglassen, werden von Laien Dosis-Wirkung-Beziehungen kaum beachtet. Ein wesentlicher Grund liegt auch in der Tatsache, dass die Expositionen in extrem niedrigen Konzentrationen erfolgen, diese Mengen aber nicht mit den menschlichen Sinnen erfasst werden können. Sie sind nur intellektuell nachvollziehbar. Häufig sind die Grenzwerte im Niedrigexpositionsbereich allerdings auch wissenschaftlich umstritten. Gleichzeitig besteht eine weit verbreitete Ignoranz gegenüber bekannten Gefahren. Eine Stärkung der Risikokompetenz bei Laien wird sich deshalb zunächst darauf beschränken müssen, für die vorhandenen Probleme ein stärkeres Bewusstsein zu schaffen.
    Keywords: toxicology ; fundamental knowledge ; dose-effect-relationships ; low concentrations ; known risks ; problem awareness ; Toxikologie ; Grundlagenkenntnisse ; Dosis-Wirkung-Beziehungen ; niedrige Konzentrationen ; bekannte Risiken ; Problembewusstsein ; ddc: 610
    Language: English
    Type: article
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  • 2
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  Mainz//2011; 56. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 6. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi); 20110926-20110929; Mainz; DOC11gmds497 /20110920/
    Publication Date: 2011-09-20
    Keywords: 3D ; Visualisierung ; Akzeptanz ; Biomedizin ; ddc: 610
    Language: German
    Type: conferenceObject
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  • 3
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    German Medical Science GMS Publishing House; Düsseldorf
    In:  GMS Krankenhaushygiene Interdisziplinär; VOL: 2; DOC49 /20071228/
    Publication Date: 2008-04-15
    Description: An overview of octenidine is given on the basis of microbicidal and virucidal activity as well as on mechanism of action and wound tolerance in comparison to other often used antiseptic agents. For the assessment of the active agent in due to its suitability for antisepsis of wounds, additionally, other biological effects were demonstrated and a toxicological assessment has been done.
    Description: Es wird ein Überblick über die mikrobiozide und viruzide Wirksamkeit einschließlich des Wirkungsmechanismus und über die Wundverträglichkeit von Octenidin im Vergleich zu anderen häufig eingesetzten antiseptischen Wirkstoffen gegeben. Zur Einschätzung des Wirkstoffs In Hinblick auf seine Eignung zur Wundantiseptik werden weitere biologische Wirkungen dargestellt und eine toxikologische Bewertung vorgenommen.
    Keywords: Octenidindihydrochlorid ; Chlorhexidin ; PVP-Iod ; Polihexanid ; Triclosan ; Benzalkoniumchlorid ; Silberverbindungen ; mikrobiozide Wirksamkeit ; Zytotoxizität ; Biokompatibilitätsindex ; Resorption ; Toxikologie ; ddc: 610
    Language: German
    Type: article
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  • 4
    Online Resource
    Online Resource
    PubMed Central | Sage Publications
    free Journals Online: 1(1)2010 – (Go to Journal)
    Publisher: PubMed Central , Sage Publications
    Electronic ISSN: 2041-7314
    Topics: Medicine
    Keywords: Biomedizin
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  • 5
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    Sage Publications
    partly licensed Journals Online: 1.1982 – (Not the last 2 years) (Go to Journal)
    Publisher: Sage Publications
    Print ISSN: 1091-5818 , 0730-0913
    Electronic ISSN: 1092-874X
    Topics: Medicine
    Keywords: Toxikologie
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  • 6
    Online Resource
    Online Resource
    Sage Publications | formerly Libertas Academica
    free Journals Online: 1.2006 – (Go to Journal)
    Publisher: Sage Publications , formerly Libertas Academica
    Electronic ISSN: 1177-2719
    Topics: Biology , Medicine
    Keywords: Biomedizin
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  • 7
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    Online Resource
    American Institute of Physics (AIP)
    partly licensed Journals Online: 1(1)1958 – 31.1988 (Go to Journal)
    partly licensed Journals Online: 6.1994 – 25.2013 (Go to Journal)
    Publisher: American Institute of Physics (AIP)
    Print ISSN: 1070-6631 , 0031-9171
    Electronic ISSN: 1089-7666
    Topics: Physics
    Keywords: Strömungsmechanik
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  • 8
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    Sage Publications
    partly licensed Journals Online: 1.1996 – (Not the last 2 years) (Go to Journal)
    Publisher: Sage Publications
    Print ISSN: 1087-0571 , 2472-5552
    Electronic ISSN: 1552-454X , 2472-5560
    Topics: Medicine
    Keywords: Biomedizin
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  • 9
    Online Resource
    Online Resource
    Sage Publications
    free Journals Online: 1.2009 – 10(4)2018 (Go to Journal)
    Publisher: Sage Publications
    Print ISSN: 1757-482X
    Electronic ISSN: 1757-4838
    Topics: Physics
    Keywords: Strömungsmechanik
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  • 10
    Online Resource
    Online Resource
    Sage Publications
    free Journals Online: 1.2017 – (Go to Journal)
    Publisher: Sage Publications
    Electronic ISSN: 2397-8473
    Topics: Medicine
    Keywords: Toxikologie
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  • 11
    Journal cover
    Online Resource
    Society of Toxicologic Pathology | Sage Publications | Sage Publications
    licenced Journals Online: 1(1)1972 – (Go to Journal)
    free Journals Online: 1.1972 – (Not the last 12 months) (Go to Journal)
    Publisher: Society of Toxicologic Pathology , Sage Publications , Sage Publications
    Print ISSN: 0094-1824 , 0192-6233
    Electronic ISSN: 1533-1601
    Topics: Medicine
    Keywords: Pathologie ; Toxikologie
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  • 12
    Journal cover
    Online Resource
    HighWire Press | Hodder Arnold | Sage Publications
    partly licensed Journals Online: 1.1981 – (Not the last 2 years) (Go to Journal)
    Publisher: HighWire Press , Hodder Arnold , Sage Publications
    Print ISSN: 0960-3271 , 0144-5952
    Electronic ISSN: 1477-0903
    Topics: Medicine
    Keywords: Toxikologie
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  • 13
    Online Resource
    Online Resource
    formerly InTech | Sage Publications
    free Journals Online: 1.2013 – (Go to Journal)
    Publisher: formerly InTech , Sage Publications
    Print ISSN: 1849-4544
    Electronic ISSN: 1849-4544
    Topics: Biology
    Keywords: Biomedizin
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  • 14
    Online Resource
    Online Resource
    Sage Publications | formerly Libertas Academica
    free Journals Online: 1.2008 – (Go to Journal)
    Publisher: Sage Publications , formerly Libertas Academica
    Electronic ISSN: 1178-2226
    Topics: Medicine
    Keywords: Bioinformatik ; Biomedizin
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  • 15
    Online Resource
    Online Resource
    formerly InTech | Sage Publications
    free Journals Online: 1.2014 – (Go to Journal)
    Publisher: formerly InTech , Sage Publications
    Print ISSN: 1849-5435
    Electronic ISSN: 1849-5435
    Topics: Biology , Medicine
    Keywords: Nanotechnologie ; Biomedizin
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  • 16
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    Online Resource
    Sage Publications
    partly licensed Journals Online: 1.1985 – (Not the last 2 years) (Go to Journal)
    Publisher: Sage Publications
    Print ISSN: 0748-2337
    Electronic ISSN: 1477-0393
    Topics: Medicine
    Keywords: Toxikologie
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  • 17
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    Online Resource
    Sage Publications
    partly licensed Journals Online: 1.1994 – (Not the last 2 years) (Go to Journal)
    free Journals Online: 24(1)2018 – (Go to Journal)
    Publisher: Sage Publications
    Print ISSN: 1753-4259 , 0968-0519
    Electronic ISSN: 1743-2839 , 1753-4267
    Topics: Medicine
    Keywords: Toxikologie
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  • 18
    Online Resource
    Online Resource
    Sage Publications
    free Journals Online: 2014 – (Go to Journal)
    Publisher: Sage Publications
    Print ISSN: 2334-4865
    Topics: Biology , Medicine
    Keywords: Biomedizin
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  • 19
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    Online Resource
    American Institute of Physics (AIP)
    partly licensed Journals Online: 1.1989 – 5(12)1993 (Go to Journal)
    Publisher: American Institute of Physics (AIP)
    Print ISSN: 0899-8213
    Topics: Physics
    Keywords: Strömungsmechanik
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