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  • Organic Chemistry  (68,947)
  • Engineering  (7,729)
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  • 1
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    American Association for the Advancement of Science (AAAS)
    In: Science
    Publication Date: 2018-03-09
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    American Association for the Advancement of Science (AAAS)
    In: Science
    Publication Date: 2018-08-17
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2018-09-07
    Description: Zeolitic imidazolate framework (ZIF) membranes are emerging as a promising energy-efficient separation technology. However, their reliable and scalable manufacturing remains a challenge. We demonstrate the fabrication of ZIF nanocomposite membranes by means of an all-vapor-phase processing method based on atomic layer deposition (ALD) of ZnO in a porous support followed by ligand-vapor treatment. After ALD, the obtained nanocomposite exhibits low flux and is not selective, whereas after ligand-vapor (2-methylimidazole) treatment, it is partially transformed to ZIF and shows stable performance with high mixture separation factor for propylene over propane (an energy-intensive high-volume separation) and high propylene flux. Membrane synthesis through ligand-induced permselectivation of a nonselective and impermeable deposit is shown to be simple and highly reproducible and holds promise for scalability.
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    American Association for the Advancement of Science (AAAS)
    In: Science
    Publication Date: 2018-08-17
    Description: Polyamide thickness and roughness have been identified as critical properties that affect thin-film composite membrane performance for reverse osmosis. Conventional formation methodologies lack the ability to control these properties independently with high resolution or precision. An additive approach is presented that uses electrospraying to deposit monomers directly onto a substrate, where they react to form polyamide. The small droplet size coupled with low monomer concentrations result in polyamide films that are smoother and thinner than conventional polyamides, while the additive nature of the approach allows for control of thickness and roughness. Polyamide films are formed with a thickness that is controllable down to 4-nanometer increments and a roughness as low as 2 nanometers while still exhibiting good permselectivity relative to a commercial benchmarking membrane.
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    American Association for the Advancement of Science (AAAS)
    In: Science
    Publication Date: 2018-04-27
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    American Association for the Advancement of Science (AAAS)
    In: Science
    Publication Date: 2018-09-14
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    American Association for the Advancement of Science (AAAS)
    In: Science
    Publication Date: 2018-09-14
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    American Association for the Advancement of Science (AAAS)
    In: Science
    Publication Date: 2018-01-19
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2018-09-14
    Description: Insects are among the most agile natural flyers. Hypotheses on their flight control cannot always be validated by experiments with animals or tethered robots. To this end, we developed a programmable and agile autonomous free-flying robot controlled through bio-inspired motion changes of its flapping wings. Despite being 55 times the size of a fruit fly, the robot can accurately mimic the rapid escape maneuvers of flies, including a correcting yaw rotation toward the escape heading. Because the robot’s yaw control was turned off, we showed that these yaw rotations result from passive, translation-induced aerodynamic coupling between the yaw torque and the roll and pitch torques produced throughout the maneuver. The robot enables new methods for studying animal flight, and its flight characteristics allow for real-world flight missions.
    Keywords: Engineering
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Keywords: Surfaces (Physics) ; Pharmaceutical technology ; Chemical engineering ; Engineering ; Nanochemistry ; Characterization and Evaluation of Materials ; Pharmaceutical Sciences/Technology ; Industrial Chemistry/Chemical Engineering ; Nanotechnology and Microengineering ; Nanochemistry ; Springer eBooks
    Description / Table of Contents: Preface -- Author Information -- Introduction -- Guide to Pharmaceutical Product Quality -- Bio-Nano: Theranostic at Cellular Level -- Moving Liposome Technology from the Bench to the Oncological Patient: Towards Performance by Design -- Fundamentals of Dry Powder Inhaler Technology -- Blending and Characterization of Pharmaceutical Powders -- Guidance on Drug Substance Particle Size Controls -- Effects of Particle Size, Surface Nature and Crystal Type on Dissolution Rate -- Amorphous APIs: Improved Release, Preparation, Characterization -- Particle Properties: Impact on the Processing and Performance of Oral Extended-Release Hydrophilic Matrix Tablets -- The Role of Particulates in Film Coating of Pharmaceutical Tablets -- Particulates in Semi-solid Pharmaceutical Products -- The Side Effects of Drugs: Nanopathological Hazards and Risks -- Subject Index
    Abstract: This edited volume brings together the expertise of numerous specialists on the topic of particles – their physical, chemical, pharmacological and toxicological characteristics – when they are a component of pharmaceutical products and formulations. The book discusses in detail properties such as the composition, size, shape, surface properties and porosity of particles with respect to how they impact the formulations and products in which they are used and the effective delivery of pharmaceutical active ingredients. It considers all dosage forms of pharmaceuticals involving particles, from powders to tablets, creams to ointments, and solutions to dry-powder inhalers, also including the latest nanomedicine products. Further, it discusses examples of particle toxicity, as well as the important subject of pharmaceutical industry regulations, guidelines and legislation. The book is of interest to researchers and practitioners who work on testing and developing pharmaceutical dosage and delivery systems
    Pages: XII, 446 p. 110 illus., 46 illus. in color. : online resource.
    ISBN: 9783319941745
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  • 11
    Keywords: Biomedical Engineering ; Orthopedics ; Engineering ; Biomedical Engineering/Biotechnology ; Orthopedics ; Computational intelligence ; Springer eBooks
    Description / Table of Contents: Chapter 1. Computer Aided Orthopaedic Surgery: Stateof-the-Art and Future Perspectives -- Chapter 2. Computer Aided Orthopaedic Surgery: incremental shift or paradigm change? -- Chapter 3. CAMISS concept and its clinical application -- Chapter 4. Surgical Navigation in Orthopaedics: Workflow and System Review -- Chapter 5. Multi-Object Model-based Multi-Atlas Segmentation Constrained Grid Cut for Automatic Segmentation of Lumbar Vertebrae from CT Images -- Chapter 6. Deep Learning-based Automatic Segmentation of the Proximal Femur from MR Images -- Chapter 7. Muscle Segmentation for Orthopaedic Interventions -- Chapter 8. 3X-Knee: A Novel Technology for 3D Pre-operative Planning and Post-operative Evaluation of TKA based on 2DX-rays -- Chapter 9. Atlas-based 3D Intensity Volume Reconstruction from 2D Long Leg Standing X-rays: Application to Hard and Soft Tissues in Lower Extremity -- Chapter 10. 3D Ultrasound for Orthopedic Interventions -- Chapter 11. A novel ultrasound-based lower extremity motion tracking system -- Chapter 12. Computer Assisted Planning, Simulation and Navigation System for Periacetabular Osteotomy -- Chapter 13. Biomechanical Optimization-based Planning of Periacetabular Osteotomy -- Chapter 14. Biomechanical Guidance System for Peri-Acetabular Osteotomy -- Chapter 15. GravityAssistedNavigationSystemforTotal HipArthroplasty -- Chapter 16. 3D Visualization and Augmented Reality for Orthopaedics -- Chapter 17. Intelligent HMI in orthopaedic navigation -- Chapter 18. Patient-Specific Surgical Guidance System for Intelligent Orthopaedics -- Chapter 19. Intelligent control for human-robot cooperation in orthopaedics surgery -- Chapter 20. Multilevel Fuzzy Control Based on Force Information in Robot-assisted Decompressive Laminectomy -- Chapter 21. Potentional risk of intelligent technologies in clinical orthopaedics -- Chapter 22. Clinical Application of Navigation in the Surgical Treatment of a Pelvic Ring Injury and Acetabular Fracture -- Chapter 23. Patient specific surgical guide for total hip arthroplasty -- Chapter 24. Computer navigation in orthopaedic tumour surgery -- Chapter 25. Sensor Based Soft Tissue Balancing in Total Knee Arthroplasty -- Chapter 26. Implant Orientation Measurement after THA Using the EOS X-Ray Image Acquisition System -- Chapter 27. 3D Printing in Spine Surgery
    Abstract: This book introduces readers to the latest technological advances in the emerging field of intelligent orthopaedics. Artificial intelligence and smart instrumentation techniques are now revolutionizing every area of our lives, including medicine. The applications of these techniques in orthopaedic interventions offer a number of potential benefits, e.g. reduced incision size and scarring, minimized soft tissue damage, and decreased risk of misalignment. Consequently, these techniques have become indispensable for various orthopaedic interventions, which has led to the emerging field of intelligent orthopaedics. Addressing key technologies and applications, this book offers a valuable guide for all researchers and clinicians who need an update on both the principles and practice of intelligent orthopaedics, and for graduate students embarking on a career in this field
    Pages: VII, 359 p. 194 illus., 141 illus. in color. : online resource.
    ISBN: 9789811313967
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  • 12
    Keywords: Biomedical Engineering ; Environmental management ; Soil conservation ; Microbiology ; Engineering ; Biomedical Engineering/Biotechnology ; Environmental management ; Soil Science & Conservation ; Applied Microbiology ; Nanotechnology and Microengineering ; Springer eBooks
    Description / Table of Contents: Module 1_Soil pollution: causes and consequences -- Module 2_Ex situ soil remediation strategies -- Module 3_In situ soil remediation strategies -- Module 4_Chemical methods -- Module 5_Biochar and soil remediation -- Module 6_Soil remediation through microbes -- Module 7_Soil remediation through algae, plants and animals -- Module 8_Nanobioremediation -- Module 9_Case studies and future prospects
    Abstract: This book presents a comprehensive collection of various in situ and ex-situ soil remediation regimes that employ natural or genetically modified microbes, plants, and animals for the biodegradation of toxic compounds or hazardous waste into simpler non-toxic products. These techniques are demonstrated to be functionally effective in connection with physical, chemical, and biological strategies. Soil and water contamination through heavy metals, hydrocarbons and radioactive wastes is of global concern, as these factors have cumulative effects on the environment and human health through food-chain contamination. The book discusses the utilization of algae, plants, plant-associated bacteria, fungi (endophytic or rhizospheric) and certain lower animals for the sustainable bioremediation of organic and inorganic pollutants. In addition, it explores a number of more recent techniques like biochar and biofilms for carbon sequestration, soil conditioning and remediation, and water remediation. It highlights a number of recent advances in nanobioremediation, an emerging technology based on biosynthetic nanoparticles. Lastly, it presents illustrative case studies and highlights the successful treatment of polluted soils by means of these strategies
    Pages: XVII, 240 p. 53 illus., 34 illus. in color. : online resource.
    ISBN: 9789811324208
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  • 13
    Keywords: Biomedical Engineering ; Microbiology ; Microbial genetics ; Microbial genomics ; Genetic Engineering ; Engineering ; Biomedical Engineering/Biotechnology ; Eukaryotic Microbiology ; Microbial Genetics and Genomics ; Genetic Engineering ; Nanotechnology and Microengineering ; Springer eBooks
    Description / Table of Contents: Chapter 1. Rhamnolipd biosurfactants and their properties -- Chapter 2. Extraction, detection and characterization of rhamnolipid biosurfactants from microorganisms -- Chapter 3. Production of rhamnolipids -- Chapter 4. Advancement of genetic engineering in rhamnolipid production -- Chapter 5. Environmental applications of rhamnolipids -- Chapter 6. Industrial applications of rhamnolipid: an innovative green technology for industry -- Chapter 7. Application of rhamnolipids in medical sciences -- Chapter 8. Role of rhamnolipids in enhanced oil recovery and oil industry -- Chapter 9. Application of rhamnolipids in agriculture and food industry -- Chapter 10. Rhamnolipid assisted synthesis of stable nanoparticles: a green approach -- Chapter 11. Quorum sensing: Its role in rhamnolipid production -- Chapter 12. Future prospects and scenario of rhamnolipids
    Abstract: This book highlights the recent developments on rhamnolipid biosurfactant, its properties, role on the natural environment and various applications. Recently, it has shown promising application in Environment, Agriculture, food, petroleum, and pharmaceutical industries due to its environment-friendly and easily degradable nature. The book emphasizes on the various techniques that are utilized for the detection and isolation of rhamnolipid biosurfactant from microorganisms. It highlights the various aspects of the rhamnolipid biosurfactants including structural characteristics, production, and its application. The book presents the current knowledge and the latest advances in the function-based metagenomics strategies to facilitate the exploration of the novel biosurfactants
    Pages: XV, 141 p. 46 illus., 35 illus. in color. : online resource.
    ISBN: 9789811312892
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  • 14
    Keywords: Engineering ; Biotechnology ; Proteins ; Regenerative Medicine ; Tissue Engineering ; Aerospace engineering ; Astronautics ; Engineering ; Aerospace Technology and Astronautics ; Biotechnology ; Crystallography and Scattering Methods ; Protein Science ; Regenerative Medicine/Tissue Engineering ; Springer eBooks
    Abstract: This book summarizes the early successes, drawbacks and accomplishments in cell biology and cell biotechnology achieved by the latest projects performed on the International Space Station ISS. It also depicts outcomes of experiments in tissue engineering, ℗ cancer research and drug design and reveals the chances that research in Space offers for medical application on Earth. This SpringerBriefs volume provides an overview on the latest international activities in Space℗ and gives an outlook on the℗ potential of biotechnological research in Space in future. This volume is written for℗ ℗ students and researchers in Biomedicine, Biotechnology and Pharmacology and may specifically be of interest to scientists with focus on protein sciences, crystallization, tissue engineering, drug design and cancer research
    Pages: XV, 109 p. 36 illus., 15 illus. in color. : online resource.
    ISBN: 9783319640549
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  • 15
    Keywords: Life sciences ; Biotechnology ; Organic Chemistry ; Biochemistry ; Cell Biology ; Life sciences ; Cell Biology ; Biochemistry, general ; Biotechnology ; Organic Chemistry ; Springer eBooks
    Description / Table of Contents: 1. Trends in bioprobe research -- 2. Cell proliferation and differentiation -- 3. Epigenetics -- 4. Apoptosis and autophagy -- 5. Adaptive and innate immune Systems -- 6. Bioprobes at a glance
    Abstract: This new edition provides the most advanced research using bioprobes on the chemical control of 1) cell cycle and differentiation, 2) epigenetics, 3) apoptosis and autophagy, and 4) immune response. The “bioprobe”, first proposed in the first edition, has become an indispensable tool for chemical biology and has substantially assisted in the investigation of complex biochemical processes of cells. New areas of investigation such as stem cell research, epigenetic research, and autophagy research have rapidly advanced in the past 10 years. Including these new findings, this second edition supplies up-to-date information on the biochemical tools called bioprobes. Data on each bioprobe, such as chemical structure, origin, function, and references, are presented as one item in this volume. Readers will easily find useful information and will be able to determine the appropriate bioprobes to investigate cell functions. The information on bioprobes and their use in research makes this book a valuable source for researchers in diverse fields. Not only scientists in academia but also in the pharmaceutical industries will discover the most important information about small molecules useful for drug discovery
    Pages: VIII, 384 p. 173 illus., 10 illus. in color. : online resource.
    Edition: 2nd ed. 2017.
    ISBN: 9784431565291
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  • 16
    Keywords: Engineering ; Quantum computers ; Spintronics ; Biomedical Engineering ; Engineering ; Biomedical Engineering ; Biomedicine general ; Quantum Information Technology, Spintronics ; Springer eBooks
    Abstract: This book addresses electron spin-qubit based quantum computing and quantum information processing with a strong focus on the background and applications to EPR/ESR techniques and spectroscopy. It explores a broad spectrum of topics including quantum computing, information processing, quantum effects in electron-nuclear coupled molecular spin systems, adiabatic quantum computing, heat bath algorithmic cooling with spins, and gateway schemes of quantum control for spin networks to NMR quantum information. The organization of the book places emphasis on relevant molecular qubit spectroscopy. These revolutionary concepts have never before been included in a comprehensive volume that covers theory, physical basis, technological basis, applications, and new advances in this emerging field. This book is an ideal resource for students and researchers in the fields of EPR/ESR, NMR and quantum computing. This book also: • Explores methods of harnessing quantum effects in electron-nuclear coupled molecular spin systems • Expertly discusses applications of optimal control theory in quantum computing • Broadens readers’ understanding of NMR quantum information processing
    Pages: VII, 255 p. 105 illus., 62 illus. in color. : online resource.
    ISBN: 9781493936588
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  • 17
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    Cham : Springer International Publishing
    Keywords: Life sciences ; Medicine ; Chemistry, Organic ; Biochemistry ; Life sciences ; Protein Science ; Biomedicine general ; Organic Chemistry ; Springer eBooks
    Description / Table of Contents: Sequences -- Structures -- Systems
    Abstract: This book describes more than 60 web-accessible computational tools for protein analysis and is totally practical, with detailed explanations on how to use these tools and interpret their results and minimal mentions to their theoretical basis (only when that is required for making a better use of them). It covers a wide range of tools for dealing with different aspects of proteins, from their sequences, to their three-dimensional structures, and the biological networks they are immersed in. The selection of tools is based on the experience of the authors that lead a protein bioinformatics facility in a large research centre, with the additional constraint that the tools should be accessible through standard web browsers without requiring the local installation of specific software, command-line tools, etc. The web tools covered include those aimed to retrieve protein information, look for similar proteins, generate pair-wise and multiple sequence alignments of protein sequences, work with protein domains and motifs, study the phylogeny of a family of proteins, retrieve, manipulate and visualize protein three-dimensional structures, predict protein structural features as well as whole three-dimensional structures, extract biological information from protein structures, summarize large protein sets, study protein interaction and metabolic networks, etc. The book is associated to a dynamic web site that will reflect changes in the web addresses of the tools, updates of these, etc. It also contains QR codes that can be scanned with any device to direct its browser to the tool web site. This monograph will be most valuable for researchers in experimental labs without specific knowledge on bioinformatics or computing
    Pages: VIII, 106 p. 40 illus. in color. : online resource.
    ISBN: 9783319127279
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  • 18
    Keywords: Medicine ; Neurochemistry ; Organic Chemistry ; Radiology ; Biomedicine ; Neurochemistry ; Organic Chemistry ; Imaging / Radiology ; Springer eBooks
    Abstract: This book explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI, genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function, and molecular-level fMRI. Comprehensive and intuitively structured, this book examines the physiological basis of fMRI, the basic principles of fMRI and its applications, and the latest advances of the technology. The final chapter discusses the field's future. fMRI: From Nuclear Spins to Brain Function is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology, and MRI physics. This book also: ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Explores a wide range of topics, covering the physical basics, physiological bases, a selection of various applications, and cutting-edge advances in fMRI ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Engages the reader with a first-person account of the development and history of the fMRI field by the authors ℗ʺ℗ ℗ ℗ ℗ ℗ ℗ ℗ ℗ Discusses fMRI applications in a variety of contexts, including fMRI of the visual system, auditory cortex, and sensorimotor system as well as the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, and℗ quantitative fMRI ℗
    Pages: XVIII, 929 p. 235 illus., 179 illus. in color. : online resource.
    Edition: 1st ed. 2015.
    ISBN: 9781489975911
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  • 19
    Publication Date: 2014-12-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Giosan, Liviu -- Syvitski, James -- Constantinescu, Stefan -- Day, John -- England -- Nature. 2014 Dec 4;516(7529):31-3. doi: 10.1038/516031a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA. ; University of Colorado, Boulder, USA, and chair of the International Geosphere-Biosphere Programme. ; University of Bucharest, Romania. ; Louisiana State University, Baton Rouge, Louisiana, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25471866" target="_blank"〉PubMed〈/a〉
    Keywords: *Climate Change ; *Conservation of Natural Resources ; Engineering ; Environmental Policy ; Floods ; Oceans and Seas ; *Rivers
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 20
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    Nature Publishing Group (NPG)
    Publication Date: 2014-09-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stern, Paul C -- England -- Nature. 2014 Sep 4;513(7516):33. doi: 10.1038/513033b.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Research Council, Washington DC, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25186891" target="_blank"〉PubMed〈/a〉
    Keywords: *Behavior ; Conservation of Energy Resources/*economics/*methods ; Engineering ; *Environmental Policy/economics ; Humans ; *Interdisciplinary Studies
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 21
    Keywords: Medicine ; Cytology ; Engineering ; Surfaces (Physics) ; Biomedicine ; Biomedicine general ; Medicine/Public Health, general ; Cell Biology ; Nanotechnology and Microengineering ; Characterization and Evaluation of Materials ; Springer eBooks
    Description / Table of Contents: 1 Presence in, and release of, nanomaterials from consumer products -- 2 Nanoparticle aggregation -- 3 Influences of nanomaterials on the barrier function of epithelial cells -- 4 Engineered nanoparticles induced brush border disruption in a human model of the intestinal epithelium -- 5 Nanoparticles: Cellular uptake and cytotoxicity. -6 Atomic force microscopy study of the interaction of DNA and nanoparticles -- 7 Intracellular signal modulation by nanomaterials -- 8 Nanomaterials: Impacts on cells and cell organelles -- 9 Design, synthesis, and functionalization of nanoparticles for therapeutic drug delivery -- 10 Preparation of nanoscale pulmonary drug delivery formulations by spray drying -- 11 Nanomedicine: The Promise and Challenges in Cancer Chemotherapy -- 12 Transgenerational effects of NMs -- 13 Stem cells and nanomaterials -- Index
    Abstract: The rapidly developing field of nanomaterials has expanded in many commercial areas.℗ More recent studies have begun to provide a foundation for understanding how nanomaterials influence cells and how they also can serve as methodological tools for studies in medicine and cell biology, include research into stem cells.℗ Recent investigations have shown affects of nanomaterials on specific subcellular structures, such as the actin-based brush border network in cells with an increasing emphasis on the barrier function of epithelial tissues.℗ ℗ While other studies have shown involvement of nanoparticles in specific cytoplasmic signal transduction events such as the rise in intracellular free calcium, a signaling event known to regulate many changes in cell architecture and function.℗ ℗ ℗ In parallel, nanomaterials are increasingly used in medicine for drug delivery, treatment of cancer, and an increasing number of new applications.℗ ℗ This book investigates these areas and also includes new methods for assessment in cell biology and medicine
    Pages: XI, 278 p. 70 illus., 42 illus. in color. : online resource.
    ISBN: 9789401787390
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  • 22
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    Cham : Springer International Publishing
    Keywords: Medicine ; Chemistry, Organic ; Life sciences ; Biomedicine ; Biomedicine general ; Life Sciences, general ; Organic Chemistry ; Springer eBooks
    Description / Table of Contents: Alkanes, Composition, Constitution and Configuration -- Functional Groups -- Electronic Structure of Organic Molecules -- Alkenes and Alkynes -- Substitutions on Saturated Carbon Atom -- Nucleophilic Additions -- Stereochemistry, Symmetry and Molecular Chirality -- Derivatives of Carboxylic Acids -- Electrophilic Substitutions -- Cycloadditions -- Organic Natural Products
    Abstract: This work provides an overview of the basics of organic chemistry for non-chemists. As such, this book should be very useful for university students of biology, molecular biology, ecology, medicine, agriculture, forestry, and other specialties where the knowledge of organic chemistry plays the important role but is not a core discipline. The book should also be of interest to non-professionals, and it may serve as a manual or repetitorium to high school teachers. ℗ The text is divided into eleven chapters on the basis of the systematization of fundamental organic reaction types, and classes of organic compounds. The first chapters comprise fundamental aspects of structural theory, reaction mechanisms, electronic structure, some basic spectroscopy, and properties of main groups of organic compounds. At the end of the book, the largest chapter contains the elements of the organic chemistry of natural products. Comparison of the reactions in the laboratory with the analogous molecular transformations in living cells will enable the reader to better understand the basic principles of biochemistry
    Pages: XIII, 179 p. 331 illus., 51 illus. in color. : online resource.
    ISBN: 9783319076058
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  • 23
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    Nature Publishing Group (NPG)
    Publication Date: 2013-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Piccolo, Stefano -- England -- Nature. 2013 Dec 12;504(7479):223-5. doi: 10.1038/504223a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Medicine, University of Padua Medical School, 35126 Padua, Italy.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24336279" target="_blank"〉PubMed〈/a〉
    Keywords: Developmental Biology ; Education/*methods ; Engineering ; Genetic Engineering
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 24
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    Nature Publishing Group (NPG)
    Publication Date: 2013-08-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pauwels, Eleonore -- England -- Nature. 2013 Aug 29;500(7464):523-4. doi: 10.1038/500523a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Woodrow Wilson International Center for Scholars, Washington DC, USA. eleonore.pauwels@wilsoncenter.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23985856" target="_blank"〉PubMed〈/a〉
    Keywords: *Communication ; Engineering ; *Metaphor ; Public Opinion ; Reproducibility of Results ; *Synthetic Biology ; *Terminology as Topic
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 25
    Keywords: Life sciences ; Agriculture ; Biochemistry ; Botany ; Engineering ; Soil conservation ; Life sciences ; Agriculture ; Plant Sciences ; Soil Science & Conservation ; Plant Biochemistry ; Engineering, general ; Control ; Springer eBooks
    Description / Table of Contents: 1 Introduction -- 2 Heterogeneity in Fields: Basics of Analyses -- 3 Sensing by Electromagnetic Radiation -- 4 Precision in Guidance of Farm Machinery -- 5 Sensing of Natural Soil Properties -- 6 Sensing of Crop Properties -- 7 Site-Specific Soil Cultivation -- 8 Site-Specific Sowing -- 9 Site-Specific Fertilizing -- 10 Site-Specific Weed Control -- 11 Site-Specific Sensing for Fungicide Spraying -- 12 Site-Specific Recording of Yields -- 13 Fusions, Overlays and Management Zones -- 14 Summary and Perspectives -- Index
    Abstract: High yields and environmental control in crop farming call for precise adaptations to local growing conditions. Treating large fields in a uniform way by high capacity machinery cannot be regarded as a sustainable method for many situations. Because differences existing within single fields must be considered. The transition from former field work carried out manually or by small implements to present day high capacity machinery caused that the farmers lost the immediate and close contact with soils and crops.℗ However, modern sensing and controlling technology can make up for this deficit.℗ High tech methods that include proximal sensing and signals from satellites can provide for controls that allow adjusting farming operations to small fractions of one ha and sometimes even down to some m2, hence in a site-specific mode. This applies to operations for soil cultivation, sowing, fertilizing and plant protection. This book deals with concepts, applications and results, and has an interdisciplinary approach that pervades all chapters
    Pages: XI, 356 p. 181 illus., 87 illus. in color. : online resource.
    ISBN: 9789400767607
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  • 26
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    Berlin, Heidelberg : Springer
    Keywords: Life sciences ; Biochemistry ; Bioinformatics ; Microscopy ; Engineering ; Life sciences ; Biochemistry, general ; Biophysics and Biological Physics ; Protein Science ; Biological Microscopy ; Bioinformatics ; Nanotechnology and Microengineering ; Springer eBooks
    Description / Table of Contents: 〈p〉Proteins -- DNA and RNA -- Carbohydrates -- Macromolecular complexes, Mechanoenzymes -- Membrane biophysics -- Electron transfer -- Ion Channels -- Receptors -- Transporters -- Biomaterials & Biosensors -- Diffraction methods -- NMR -- EPR -- Optical spectroscopy -- X-ray spectroscopy -- Single molecule methods -- Computational Biophysics -- Thermodynamics -- Kinetics -- Mass spectrometry -- Molecular shape & hydrodynamics -- Electron microscopy -- Live cell & in vivo imaging -- Cell biophysics.〈/p〉
    Abstract: 〈p〉The Encyclopedia of Biophysics is envisioned both as an easily accessible source of information and as an introductory guide to the scientific literature. It includes entries describing both Techniques and Systems.℗ 〈br〉In the Techniques entries, each of the wide range of methods which fall under the heading of Biophysics are explained in detail, together with the value and the limitations of the information each provides. Techniques covered range from diffraction (X-ray, electron and neutron) through a wide range of spectroscopic methods (X-ray, optical, EPR, NMR) to imaging (from electron microscopy to live cell imaging and MRI), as well as computational and simulation approaches.〈br〉In the Systems entries, biophysical approaches to specific biological systems or problems ́€“ from protein and nucleic acid structure to membranes, ion channels and receptors ́€“ are described. These sections, which place emphasis on the integration of the different techniques, therefore provide an inroad into Biophysics from a biological more than from a technique-oriented physical/chemical perspective.℗ 〈br〉Thus the Encyclopedia is intended to provide a resource both for biophysicists interested in methods beyond those used in their immediate sub-discipline and for those readers who are approaching biophysics from either a physical or biological background.℗ ℗ 〈/p〉〈p〉
    ISBN: 9783642167126
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  • 27
    Keywords: Engineering ; Ethics ; Biomedical Engineering ; Engineering ; Biomedical Engineering ; Ethics ; Springer eBooks
    Description / Table of Contents: Preface -- Ethical practices and engineering -- Ethics & biomedical engineering practice & research: origins of principles & consent -- Ethical considerations in clinical engineering -- Ethics of biomaterials for implants -- Ethics and data mining in biomedical engineering -- Whistle blowing: an option or an obligation? -- Index
    Abstract: Over the last few decades, there are increasing public awareness of adverse events involving engineering failures that not only led to monetary losses but also more importantly, human injuries and deaths. Whilst it is vital for an engineering professional or student to acquire the necessary technical knowledge and skills in their respective field, they must also understand the ethical essences that are relevant to their profession. Engineering professionals like biomedical engineers, need to appreciate the fundamentals of best practices and recognise how any derivation from such practices can have undesirable impacts on human lives. ℗ Through this book, it is hoped that readers would draw the relevance between the study of ethics and biomedical engineering. The book would be a useful source and reference for college-level and university-level students. Moreover, the contents are written so as to also provide valuable insights even for existing biomedical engineers and those enrolled in continual engineering education program. The following aspects of biomedical engineering are covered in the book: ℗ ℗ʹ℗ ℗ ℗ Research and clinical studies involving medical devices. ℗ʹ℗ ℗ ℗ Working in a healthcare establishment. ℗ʹ℗ ℗ ℗ Developing and servicing medical instrumentations. ℗ʹ℗ ℗ ℗ Choice of biomaterials to develop implants. ℗ʹ℗ ℗ ℗ Performing statistical analyses and data mining
    Pages: : digital.
    ISBN: 9781461469131
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  • 28
    Keywords: Medicine ; Spectroscopy ; Biotechnology ; Chemistry, Organic ; Chemistry, Physical organic ; Biochemistry ; Biomedicine ; Biomedicine general ; Spectroscopy/Spectrometry ; Biotechnology ; Physical Chemistry ; Organic Chemistry ; Biochemistry, general ; Springer eBooks
    Description / Table of Contents: The basis of Nuclear Magnetic Resonance Spectroscopy -- Spectroscopic parameters in Nuclear Magnetic Resonance -- Basic NMR experiments -- Biomolecular NMR
    Abstract: This book intends to be an easy and concise introduction to the field of nuclear magnetic resonance or NMR, which has revolutionized life sciences in the last twenty years. A significant part of the progress observed in scientific areas like Chemistry, Biology or Medicine can be ascribed to the development experienced by NMR in recent times. Many of the books currently available on NMR deal with the theoretical basis and some of its main applications, but they generally demand a strong background in Physics and Mathematics for a full understanding. This book is aimed to a wide scientific audience, trying to introduce NMR by making all possible effort to remove, without losing any formality and rigor, most of the theoretical jargon that is present in other NMR books. Furthermore, illustrations are provided that show all the basic concepts using a naive vector formalism, or using a simplified approach to the particular NMR-technique described. The intention has been to show simply the foundations and main concepts of NMR, rather than seeking thorough mathematical expressions
    Pages: XII, 115 p. 36 ill. : digital.
    ISBN: 9789400769762
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  • 29
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    Dordrecht : Springer
    Keywords: Medicine ; Spectroscopy ; Chemistry, Organic ; Chemistry, Physical organic ; Chemistry ; Biomedicine ; Biomedicine general ; Organic Chemistry ; Physical Chemistry ; Spectroscopy/Spectrometry ; Organometallic chemistry ; Electrochemistry ; Springer eBooks
    Description / Table of Contents: Molecular structures -- An overview of synthetic methods for preparation of nitrosoaromatic compounds -- Molecular properties and spectroscopy -- Organometallic compounds -- Bilological systems
    Abstract: This volume will present the reader with an update on the scientific research on organic chemistry of nitroso compounds that was performed in the last two decades. The overview will include the original synthetic applications of nitroso compounds, but will also cover the discovery of novel physico-chemical phenomena and their potential future uses. The properties that form the basis for this technological potential originate from the intriguing property of C-nitroso molecules to form dimers through the formation of a relatively weak nitrogen-nitrogen double bond. The equilibrium between the different monomeric and dimeric forms, which appears under controlled environmental parameters, opened new areas of research in organic chemistry.The novel paradigm presented in this volume includes insight into the original problem of organic reactivity and synthesis, but also sheds light on the solid-state reaction mechanisms. A number of fascinating photochemical, electrochemical, supramolecular, and biological properties, as well as advanced techniques in spectroscopy, now enables us to use these compounds as molecular models for studying a number of general chemical concepts.℗
    Pages: : digital.
    ISBN: 9789400763371
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  • 30
    Keywords: Engineering ; Agriculture ; Applied Ecology ; Renewable energy sources ; Farm economics ; Engineering ; Renewable and Green Energy ; Agriculture ; Applied Ecology ; Agricultural Economics ; Springer eBooks
    Abstract: A number of driving forces, including the soaring global crude oil prices and environmental concerns in both developed and developing nations has triggered a renewed interest in the recent years on the R&D of biofuel crops. In this regard, many countries across the globe are investing heavily in the bioenergy sector for R&D to increase their energy security and reduce their dependence on imported fossil fuels. Currently, most of the biofuel requirement is met by sugarcane in Brazil and corn in the United States, while biodiesel from rapeseed oil in Europe. Sweet sorghum has been identified as a unique biofuel feedstock in India since it is well adapted to Indian agro-climatic conditions and more importantly it does not jeopardize food security at the cost of fuel. Sweet sorghum [Sorghum bicolor (L.) Moench] is considered as a SMART new generation energy crop as it can accumulate sugars in its stalks similar to sugarcane, but without food¬¬-fuel trade-offs and can be cultivated in almost all temperate and tropical climatic conditions and has many other advantages. The grain can be harvested from the panicles at maturity. There is no single publication detailing the agronomic and biochemical traits of tropical sweet sorghum cultivars and hybrid parents. Hence, an attempt is made in this publication- “Characterization of improved sweet sorghum cultivars” to detail the complete description of cultivars. This book serves as a ready reference on the detailed characterization of different improved sweet sorghum genotypes following the PPVFRA guidelines for the researchers, entrepreneurs, farmers and other stakeholders to identify the available sweet sorghum cultivars and understand their yield potential in tropics
    Pages: IX, 130 p. 48 illus., 45 illus. in color. : digital.
    ISBN: 9788132207832
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    Nature Publishing Group (NPG)
    Publication Date: 2012-04-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Boesch, Donald -- England -- Nature. 2012 Apr 17;484(7394):289. doi: 10.1038/484289a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Maryland Center for Environmental Science, Cambridge. boesch@umces.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22517129" target="_blank"〉PubMed〈/a〉
    Keywords: Conservation of Natural Resources/trends ; Disasters/economics/prevention & control ; Ecology/trends ; Ecosystem ; Engineering ; Federal Government ; Gulf of Mexico ; Petroleum Pollution/adverse effects/economics/legislation & ; jurisprudence/*prevention & control ; *Risk Management/trends ; United States
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 32
    Keywords: Chemistry ; Biotechnology ; Microbiology ; Cell Culture ; Engineering ; Renewable energy sources ; Chemistry ; Applied Microbiology ; Environmental Science and Engineering ; Biotechnology ; Cell Culture ; Nanotechnology and Microengineering ; Renewable and Green Energy ; Springer eBooks
    Description / Table of Contents: 〈p〉Dedication -- Introduction to The Science of Algal Fuels: Psychology, Geology, Biophotonics, Genomics and Nanotechnology -- Preface to The Science of Algal Fuels: Psychology, Geology, Biophotonics, Genomics and Nanotechnology -- Foreword: The Production of Algal Biofuels -- Acknowledgements -- PART 1:METHODS AND WAYS OF RESEARCH -- Quitting cold turkey: rapid oil independence for the USA -- Algal biorefinery: sustainable production of biofuels and aquaculture feed? -- Approaches and prospectives for algal fuel -- From isolation of potential microalgal strains to strain engineering for biofuel -- Integrated approach to algae production for biofuel utilizing robust algal species -- Biological constraints on the production of microalgal-based biofuels -- Adapting mass algaculture for a northern climate -- Nanotechnology for algal biofuels -- From algae to biofuel - engineering aspects -- Making fuel from algae: identifying fact amid fiction -- Algal oils: biosynthesis and uses -- Algal biofuel production through integrated biorefinery -- PART 2: PRODUCTION OF BIODIESELS AND HYDROGEN -- Dinoflagellates as feedstock for biodiesel production -- Biodiesel production from microalgae: methods for microalgal lipid assessment with emphasis on the use of flow cytometry -- Approaches to and perspectives on biodiesel and oil production using algae in Mexico -- Biodiesel production from microalgae: a mapping of articles and patents; Biotechnology of hydrogen production with the microalga Chlamydomonas reinhardtii; PART 3: ALGAE FOR BIOFUEL PRODUCTION -- How to breed diatoms: examination of two species with contrasting reproductive biology -- Fuel from seaweeds: rationale and feasibility -- The contribution of diatoms to worldwide crude oil deposits -- Photobiology and lipid metabolism in algae -- Metabolic pathways in green algae with potential value for biofuels production -- PART 4: FROM WASTE WATER TO FUEL PRODUCTION -- Wastewater treatment pond algal production for biofuel -- Wastewater treatment integrated with algae production for biofuel -- Sub-and supercritical water based processes for microalgae to biofuels.〈/p〉
    Abstract: 〈p〉This volume covers and updates the ́€œhot́€ topic of biofuels, with numerous international meetings, conferences, congresses, and books on biofuels. Our 61 experts from several countries contributed 26 chapters to The Science of Algal Fuels. Each chapter has been composed as a review article and contains many references for further studies and has been peer reviewed. The target audience of this volume is workers in biofuels, graduate students in biochemistry and lecturers of phycology and biochemistry of the algal world. Algae, seaweeds and cyanobacteria, who are our stars in this book, live in marine and terrestrial habitats and require the Sun for energy, CO2 and aqueous surroundings. Since it is easy to culture algae in a large scale and they yield abundant biomass in a short period, there are farms that grow them in ponds for extracting their natural products. Micro and macro (seaweeds) can produce cheap and plentiful biofuel, biodiesel, or ethanol. The phycological yield to synthesize ethanol is 7.5 times higher than from a similar area of a sugar cane field. Biofuel (such as algal products) may soon be cheaper than the commercial pumping of underground and sea bottom fossil-oil, which causes more air pollution and depends upon political decisions from unstable countries. Industry seeks cheaper and more stable sources of fuel and algal fuel might be a good solution. Thus biofuel (biodiesel, oils, ethanol) might free us from unstable regimes with their ́€œdark gold́€ sources, and from up and down oil prices. Unfortunately we have not yet reached this level as yet in spite of numerous contestants in this developing research. The industry is at present not in full gear to produce a substantial yield of biofuel from algae. Algal fuel is still a long range of strategy that will involve more R&D.℗ Our hope is that this book will encourage the workers in this field to reach this ́€œpromised land́€ of algal biofuels in the not too distant future.〈/p〉
    ISBN: 9789400751101
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    Keywords: Life sciences ; Toxicology ; Chemistry, Organic ; Pharmacy ; Oceanography ; Biochemistry ; Aquatic biology ; Life sciences ; Biochemistry, general ; Organic Chemistry ; Freshwater & Marine Ecology ; Oceanography ; Pharmacology/Toxicology ; Pharmacy ; Springer eBooks
    ISBN: 9789048138340
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  • 34
    Keywords: Physics ; Biotechnology ; Data mining ; Engineering ; Physics ; Nanoscale Science and Technology ; Condensed Matter Physics ; Data Mining and Knowledge Discovery ; Biotechnology ; Nanotechnology and Microengineering ; Springer eBooks
    ISBN: 9789400724884
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  • 35
    Keywords: Economics ; Computer science ; Physics ; Engineering ; Environmental economics ; Economics/Management Science ; Environmental economics ; Environmental Monitoring/Analysis ; Economic Theory ; Complexity ; Models and Principles ; Springer eBooks
    Edition: 2nd ed.
    ISBN: 9781461422099
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  • 36
    Keywords: Engineering ; Biology / Philosophy ; Philosophy ; Developmental Biology ; Evolution (Biology) ; Physics ; Engineering ; Complexity ; Cosmology ; Developmental Biology ; Evolutionary Biology ; Philosophy of Biology ; Philosophy of Religion ; Springer eBooks
    Pages: : digital.
    ISBN: 9789400741560
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  • 37
    Keywords: Life sciences ; Chemistry, Organic ; Carbohydrates ; Biochemistry ; Proteomics ; Cytology ; Cell Membranes ; Life sciences ; Biochemistry, general ; Organic Chemistry ; Carbohydrate Chemistry ; Cell Biology ; Membrane Biology ; Proteomics ; Springer eBooks
    Pages: : digital.
    ISBN: 9781461433811
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  • 38
    Publication Date: 2011-10-15
    Description: A current limitation in nanoparticle superlattice engineering is that the identities of the particles being assembled often determine the structures that can be synthesized. Therefore, specific crystallographic symmetries or lattice parameters can only be achieved using specific nanoparticles as building blocks (and vice versa). We present six design rules that can be used to deliberately prepare nine distinct colloidal crystal structures, with control over lattice parameters on the 25- to 150-nanometer length scale. These design rules outline a strategy to independently adjust each of the relevant crystallographic parameters, including particle size (5 to 60 nanometers), periodicity, and interparticle distance. As such, this work represents an advance in synthesizing tailorable macroscale architectures comprising nanoscale materials in a predictable fashion.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Macfarlane, Robert J -- Lee, Byeongdu -- Jones, Matthew R -- Harris, Nadine -- Schatz, George C -- Mirkin, Chad A -- New York, N.Y. -- Science. 2011 Oct 14;334(6053):204-8. doi: 10.1126/science.1210493.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, Northwestern University, Evanston, IL 60208, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21998382" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Crystallization ; Crystallography ; DNA/*chemistry ; Engineering ; Metal Nanoparticles/*chemistry ; Microscopy, Electron, Transmission ; Nucleic Acid Hybridization ; Oligonucleotides/chemistry ; Particle Size ; Scattering, Small Angle ; Thermodynamics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 39
    Publication Date: 2011-10-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Birch, Kristi -- Blackburn, Carol -- Brody, Linda -- Wallace, Patricia -- New York, N.Y. -- Science. 2011 Oct 28;334(6055):467-8. doi: 10.1126/science.1196983.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉The Johns Hopkins University Center for Talented Youth, Baltimore, MD 21209, USA. kbirch@jhu.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22034426" target="_blank"〉PubMed〈/a〉
    Keywords: Awards and Prizes ; Engineering ; *Internet ; Mathematics ; *Science ; Technology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 40
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2011-06-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Merali, Zeeya -- New York, N.Y. -- Science. 2011 Jun 17;332(6036):1376-7. doi: 10.1126/science.332.6036.1376.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21680824" target="_blank"〉PubMed〈/a〉
    Keywords: Biomedical Engineering ; China ; Engineering ; *Equipment Design ; History, 20th Century ; History, 21st Century ; Housing ; Spacecraft ; *Stents
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 41
    Keywords: Chemistry ; Chemistry, Organic ; Chemistry ; Organic Chemistry ; Springer eBooks
    Pages: : digital
    ISBN: 9781441972705
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  • 42
    Keywords: Life sciences ; Chemistry, Organic ; Nucleic Acids ; Biochemistry ; Life sciences ; Nucleic Acid Chemistry ; Protein Science ; Organic Chemistry ; Springer eBooks
    Pages: : digital
    ISBN: 9783642169311
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  • 43
    Keywords: Medicine ; Toxicology ; Pharmaceutical technology ; Chemistry, Organic ; Chemical engineering ; Biochemistry ; Biomedicine ; Pharmacology/Toxicology ; Pharmaceutical Sciences/Technology ; Organic Chemistry ; Medicinal Chemistry ; Medical Biochemistry ; Industrial Chemistry/Chemical Engineering ; Springer eBooks
    Pages: : digital
    ISBN: 9783034801256
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  • 44
    Keywords: Physics ; Biochemical engineering ; Microreactors ; Engineering ; Physics ; Fluid- and Aerodynamics ; Microengineering ; Engineering Thermodynamics, Heat and Mass Transfer ; Biochemical engineering ; Springer eBooks
    Pages: : digital
    ISBN: 9789048190294
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  • 45
    Keywords: Medicine ; Toxicology ; Public Health ; Engineering ; Environmental Medicine ; Biomedicine ; Biomedicine general ; Nanotechnology and Microengineering ; Public Health/Gesundheitswesen ; Environmental Health ; Pharmacology/Toxicology ; Springer eBooks
    Pages: : digital
    ISBN: 9789048126323
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  • 46
    Keywords: physics ; Condensed matter ; Engineering ; Materials ; Particles (Nuclear physics) ; Superconductivity ; Materials Science ; Physics and Applied Physics in
    Abstract: We study quantum signatures of the chaotic dynamics in typical two-dimensional Hamiltonian systems, where regular and chaotic...
    Type of Publication: Book chapter
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  • 47
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Chirality 10 (1998), S. 492-498 
    ISSN: 0899-0042
    Keywords: racemate ; enantiomer ; HPLC ; chiral stationary phase ; benzoylcellulose ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The advantages that can be gained from derivatization of various racemic aliphatic and aromatic alcohols prior to enantiomeric chromatographic separation have been systematically investigated for a series of benzoate derivatives. Three cellulose-based CSPs available in the pure polymeric form - tribenzoyl cellulose (TBC), meta-methylbenzoyl cellulose (MMBC), and para-methylbenzoyl cellulose (PMBC) - were selected and several benzoate derivatives varying in the nature and the position of the substituent on the benzoyl group were prepared and analysed. TBC clearly gives the broadest application range, and among the different benzoate esters the best selectivity was generally obtained with either the 4-methoxybenzoate or the 4-methylbenzoate derivatives. Based on these results, some empirical rules could be formulated for optimizing the enantiomeric separation of racemic alcohols, which make up one of the most important classes of chemical substances used as drugs and biocides, or as building blocks for their synthesis. An application of this approach to the preparative separation of the enantiomers of a drug intermediate is also shown. Chirality 10:492-498, 1998. © 1998 Wiley-Liss, Inc.
    Additional Material: 5 Ill.
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  • 48
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Chirality 10 (1998), S. 507-512 
    ISSN: 0899-0042
    Keywords: chiroptical method ; drug analysis ; β-lactam antibiotics ; CD spectroscopy ; human fluids ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A study of the applicability of circular dichroism (CD) for the determination of drug levels in human serum is described and a new method for the quantitative determination of optically active absorbing drugs having Cotton effects at wavelengths above 250 nm in human serum and/or plasma is proposed. The principal advantages of this method are speed, economy, and simplicity, no derivatization or chromatographic separation steps being needed. The validity of the CD determination was confirmed by analysis of variance, β-lactam antibiotics being chosen as model drugs. In addition, the validation studies performed confirm the accuracy and precision of the proposed method. For β-lactam antibiotics lacking Cotton effects above 250 nm, an alternative method based on the extraction of the drug from serum is considered. Chirality 10:507-512, 1998. © 1998 Wiley-Liss, Inc.
    Additional Material: 5 Ill.
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  • 49
    ISSN: 0899-0042
    Keywords: chiral HPLC ; quantitative substituent effect ; recognition mechanism ; fluorene derivative-chiral separation ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The chromatographic parameters for 12 structurally related compounds in the 4a-methyl-2,3,4,4a-tetrahydro-1H-fluorene and 4a-methyl-1,2,3,4,4a,9a-hexahydro-fluoren-9-one series are reported on CTA-I and Chiralcel OJ chiral stationary phases. Arrangement of the k' values according to configurationally related enantiomer series (Class I and Class II) and not according to the actual order of elution, allows the treatment of the data by linear correlation with structure and substituent effect. A detailed analysis of the capacity factor variation with respect to the structural changes shows clearly that the framework and substitution effects do not result in the same response on the two cellulose ester chiral stationary phases. More interestingly, it emerges that chiral discimination may be attributed to certain areas of the molecule, these areas being different in the interaction within CTA-I and Chiralcel OJ. Furthermore, our analysis points out the relevance of attempting to develop quantitative relationships for configurationally related series of enantiomers (in our case Class I and Class II), the main effort being devoted to the understanding of the capacity factor variation in each class rather than of the α values, which are derived entities. Chirality 10:522-527, 1998. © 1998 Wiley-Liss, Inc.
    Additional Material: 4 Ill.
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  • 50
    ISSN: 0899-0042
    Keywords: asymmetric hydrogenation ; non-coded amino acids ; enantioselectivity ; dipeptides ; diastereoselectivity ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The enantiomers of Propranolol, Pindolol, and Carazolol, well-known β-blockers, have been used to prepare cationic aminophosphine phosphinite rhodium complexes. Propraphos-Rh and Pindophos-Rh are very efficient catalysts in the asymmetric hydrogenation of N-Boc-protected unusual dehydroamino acid derivatives. Carazolol-Rh is less suitable in both activity and enantioselectivity. Under the same conditions, N-Boc-protected dehydrodipeptides are hydrogenated with diastereoselectivities between 70 and 90% de. Chirality 10:535-539, 1998. © 1998 Wiley-Liss, Inc.
    Additional Material: 1 Ill.
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  • 51
    ISSN: 0899-0042
    Keywords: quinuclidine derivatives ; chromatographic separation ; borane complexes ; fractional crystallization ; resolution ; X-ray crystallography ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The four stereoisomers of the antimuscarinic 3-(2,3-dihydrobenzofuran-2-yl)quinuclidine have been prepared by a method involving chromatographic separation of the racemic diastereoisomers as borane complexes. The relative and absolute configurations of the stereoisomers were determined by X-ray crystallographic methods. The crystal structure of (2′R,3R)-3-(2,3-dihydrobenzofuran-2-yl)quinuclidine · HCl · H2O contains two independent molecules with different conformations of both the quinuclidine moiety and the dihydrofuran ring. Chirality 10:813-820, 1998. © 1998 Wiley-Liss, Inc.
    Additional Material: 5 Ill.
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  • 52
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Chirality 10 (1998), S. 1-2 
    ISSN: 0899-0042
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: No abstract.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 53
    ISSN: 0899-0042
    Keywords: α-hydroxy acids ; chiral stationary phases ; enantiomer resolution ; copper ternary complexes ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Direct separation of several α-hydroxy acid racemic mixtures was performed by the aid of ligand exchange chromatography using L-hydroxyproline chemically bound to silica stationary phase and aqueous solutions of copper (II) sulphate as a mobile phase. The elution order of the D- and L-enantiomers of α-hydroxy acids is interpreted in terms of a modified Davankov's rule. Several aspects of the Davankov's model of selectand-Cu(II)-selector ternary complexes are discussed based on the theoretical calculations within the quantum mechanical semiempirical and density functional theories. Chirality 10:821-830, 1998. © 1998 Wiley-Liss, Inc.
    Additional Material: 9 Ill.
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  • 54
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Chirality 10 (1998), S. 3-7 
    ISSN: 0899-0042
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: No abstract.