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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Alpha-fetoprotein (AFP) has been estimated in 358 specimens of amniotic fluid from 221 pregnancies terminating in the delivery of a normal infant and in the amniotic fluid from 21 pregnancies in which the fetus turned out to have a neural tube defect. When the fetus had a neural tube defect, AFP levels before 36 weeks were raised above the 95th centile of normal controls with the exception of one patient in whom the fetus had a closed neural tube defect.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Concentrations of amino acids and related compounds in 111 samples of amniotic fluid obtained by transabdominal amniocentesis, and 89 corresponding maternal plasmas were measured using a Beckman 121 Automatic amino acid analyzer. Thirty-six amino acids and related compounds were identified in amniotic fluid and/or maternal plasma samples. The concentration of eight amino acids (Phe, Tyr, Val, Leu, He, Lys, Ala and His) decreased towards the end of pregnancy in amniotic fluid but the Phe/Tyr ratio remained constant. Thirteen amino acids (Gly, Ser, Thr, Asp, Asn, Glu, Arg, Met, Pro, Orn, Ans, Tau, Cit) showed no significant change from the 10th to the 40th week of gestation, while ten were present in trace amounts during the same period (lMeh, 3Meh, PSer, PEam, Asp, αAAD, αABA, 1/2CyS, Cyth, Hyp). Our results show that the great variation in lysine concentration between the 10th to the 20th week does not permit fetal age correlation studies. We found that alanine was measurable both in early and late pregnancy with a mean of 0.4 mM. at 10 weeks and 0.1 mM. at 40 weeks. The mean serine, glycine and arginine concentrations showed no statistically significant variation from the 10th to the 40th week of pregnancy. Hydroxyproline was found at a concentration of less than 0.01 mM. in amniotic fluid from the 22nd to the 37th week of pregnancy in our study, but homocarnosine was too low for accurate measurement. Ethanolamine was present at levels of less than 0. 03 mM. in 27 amniotic fluid and 8 maternal plasma samples throughout gestation. There was a marked elevation of amino acid concentrations in amniotic fluid obtained from sacs containing two fetuses. The glycine concentration in one amniotic fluid sample obtained around the 45th day of gestation was 6.1 mM.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Plasma oestradiol showed a two- to three-fold rise above the mean basal level by six hours after a single intravenous injection of synthetic Luteinizing Hormone and Follicle Stimulating Hormone Releasing Hormone (LH-RH/FSH-RH) in nine out of twelve patients with secondary amenorrhoea. Of the remaining three patients, two had persistently high basal plasma gonadotrophins in keeping with a diagnosis of premature menopause and one patient had secondary amenorrhoea of seven years' duration. It is suggested that a six-hour plasma oestradiol estimate be used as the endpoint of the LH-RH/FSH-RH test in order to assess the pituitary-ovarian axis. If a less than two-fold increase in plasma oestradiol is found, pituitary reserve can be more intensively studied by assaying plasma follicle stimulating hormone (FSH) and luteinizing hormone (LH).
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 32-year-old patient with chronic vaginal candidiasis was treated with 8 units of Transfer Factor (TF). Smears and cultures for Candida albicans became negative. Vaginal discharge and itching ceased, and the clinical condition of the vagina improved. Formerly negative delayed type skin tests with candidin converted to positive and Candida lymphocyte stimulation became measurable, suggesting that a defective cellular immunity towards Candida aas restored by TF. Candidiasis reappeared a few months after the last dose of TF when measurable cellular immunity towards candidin was still present. The condition responded rapidly to a local treatment with 5-fluoro-cytosin.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A case is described of obstructed labour due to a pelvic hydatid cyst which was treated by Caesarean section followed by vaginal evacuation of the cyst.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Spontaneous complete transurethral inversion of the bladder, occurring in labour is rare. Three cases appear to have been described previously and a fourth is reported here.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Pneumoperitoneum for laparoscopy was induced in a series of 105 patients by inserting the Verres needle through the uterine fundus. The results indicate that this technique is simple and safe.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of long-term treatment with oestrogen/progestogen preparations were assessed in 16 patients presenting with hirsutism but without virilism; these comprised 12 patients with “idiopathic” hirsutism, one of whom had amenorrhoea due to pituitary gonadotrophin deficiency, and four patients with the Stein-Leventhal syndrome. Regression of hair growth was observed only in those with normal ovaries and elevated urinary excretion of 17-oxosteroids. Patients who responded favourably to a preparation with a high oestrogen content failed to do so when a low oestrogen preparation was substituted.
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A primigravida presenting with hydramnios at 34 weeks' gestation was found to have distended fluid-filled spaces inside the fetal abdomen on ultrasonic B scan. Amniography showed a normal fetal soft-tissue outline and normal scalp thickss with the absence of contrast medium in the fetal gastro-intestinal tract at two-and-a-half hours. It is suggested that this combination of findings is, if not diagnostic, at least highly suggestive of duodenal atresia and that the intrauterine diagnosis of this condition may enable corrective surgery to be carried out early before neonatal electrolyte disturbances affect the prognosis.
    Type of Medium: Electronic Resource
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